rewire.itbenchmarks
Evaluation

OncoVI: Guideline SOP variants

Scoped author-reported evaluation; read protocol and cohort limits before comparing.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-09-30-e37e3ab1284d · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 8 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
81% accuracy
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, accuracy; subgroup values correspond to Supplemental Table S6
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
83% benign_sensitivity
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, benign_sensitivity; subgroup values correspond to Supplemental Table S6
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
83.1% missense_accuracy
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, missense_accuracy; subgroup values correspond to Supplemental Table S6
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
82% oncogene_accuracy
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, oncogene_accuracy; subgroup values correspond to Supplemental Table S6
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
88% oncogenic_sensitivity
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, oncogenic_sensitivity; subgroup values correspond to Supplemental Table S6
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
0.87 score_correlation
correlation coefficient · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Figure 2B, concordant variants only
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
77.7% truncating_accuracy
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, truncating_accuracy; subgroup values correspond to Supplemental Table S6
Configuration: OncoVI 2026 publication configurationProtocol: OncoVI three-class assessment: Guideline SOP variants
Dataset: Guideline SOP variants
87.1% tsg_accuracy
percent · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

OncoVI: Guideline SOP variants

Not reported

Aggregation: Not reported

Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, Guideline SOP variants, tsg_accuracy; subgroup values correspond to Supplemental Table S6

Source checking is not independent reproduction. Release 2026-09-30-e37e3ab1284d.

Evaluation procedure

Not reported

Configuration
OncoVI 2026 publication configuration
Protocol
OncoVI three-class assessment: Guideline SOP variants
Dataset
Guideline SOP variants
origin
Author-reported evaluation
configuration
Not reported
protocol id
uc-clinical-20260930-oncovi-sop-protocol
dataset version
Not reported
split
Not reported
population
Guideline SOP variants
inputs
Not reported
adaptation
Not reported
metric implementation
Source-defined endpoint; see result source_locator
aggregation
Not reported
budget
Not reported

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Not reported
Adaptation
Not reported
Scoring implementation
Source-defined endpoint; see result source_locator

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-30-e37e3ab1284d
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Not reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
Not reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
Not reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Source-defined endpoint; see result source_locator
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.population
Guideline SOP variants
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
uc-clinical-20260930-oncovi-sop-protocol
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.split
Not reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
author_reported
Context-only references
Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology

Original source ↗

Results, Guideline SOP variants

Version: 2026 final full text in Europe PMC XML
Retrieved: 2026-09-30T21:23:41Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.origin

Source artifact SHA-256: 1ced323acfac29704bccfd990cc57692770c324ae598983c6973d271aaaf48b2

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-30-e37e3ab1284d · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: uc-clinical-20260930-oncovi-sop-evaluation

areas
dna-genomes
contexts
clinical_research
origin
author_reported
source locator
Results, Guideline SOP variants
published score reproduction
false
review
method: automated_source_review; reviewer: Codex clinical coverage worker; date: 2026-09-30; note: Transcription from inspected primary source. No execution, independent replication or human scientific review.; source id: uc-clinical-20260930-source-oncovi
comparison
protocol id: uc-clinical-20260930-oncovi-sop-protocol; dataset version: Not reported; split: Not reported; population: Guideline SOP variants; inputs: Not reported; adaptation: Not reported; metric implementation: Source-defined endpoint; see result source_locator; aggregation: Not reported; budget: Not reported
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