Third-party measurement of entrant designs, transcribed from the pinned source; not reproduced.
1 evaluation · 1 result. Different protocols are not a single leaderboard.
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: BindCraft with helical loss -2.0 as entered in Adaptyv round 2 | Protocol: Adaptyv EGFR competition cell-free expression rate Dataset: Adaptyv EGFR competition round 2 tested designs | all ten showed high expression rates Count (designs with high expression) count · higher Uncertainty: Not applicable: An exact count. Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceuc-binder-20261022-protocol-adaptyv-expression Aggregation: Not reported Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) · Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' |
Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.
0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.
Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified
Exact outcomes, predictions, identifiers and evaluator are connected.
Missing or unresolved evidence
Verified: Not verified
Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.
Missing or unresolved evidence
Verified: Not verified
A pinned recipe describes the inputs, environment and resource requirements.
Missing or unresolved evidence
Verified: Not verified
Separate data and exposure records support an independent test.
Missing or unresolved evidence
Verified: Not verified
Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.
No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.
Adaptyv EGFR competition cell-free expression rate
Metadata review: source checked. Unreported conditions prevent automatic comparisons.
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
19 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation Not reported Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | missing or unspecified No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: aggregation Over the designs tested in the stated round Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: budget 10 designs tested Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: dataset version Adaptyv EGFR Binder Design Competition round 2, results revealed December 2024 Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: inputs EGFR structure; entrants chose their own inputs and workflow Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: metric implementation designs with high expression Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: population 10 designs tested Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: protocol id uc-binder-20261022-protocol-adaptyv-expression Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Comparison: split Not reported Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | missing or unspecified No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
| Denominator 10 Context-only references | Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) Section 3.1: 'Ten out of the author's submitted beta sheeted designs were tested and - given the lower overall expression rate of the competition in R1 - surprisingly all ten showed high expression rates' Version: bioRxiv preprint version 1 | not individually reviewed No individual claim review recorded independent paper Source has a recorded evidence concern. Consult its source page before using the claim. Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact. |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: uc-binder-20261022-eval-adaptyv-bindcraft-r2-expression