Published comparison transcribed from the pinned source; not reproduced.
1 evaluation · 21 results. Different protocols are not a single leaderboard.
Protocol: ONT HCC1395 tumour-only, 25x to 75x, somatic SNVs (Chen et al. 2025 Supplementary Table 2b) · Dataset: HCC1395 tumour ONT R10.4.1 WGS (ClairS-TO benchmark)
Sorted by AUPRC (SNV only, tumour-only, 25x tumour coverage) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | AUPRC (SNV only, tumour-only, 25x tumour coverage) | AUPRC (SNV only, tumour-only, 50x tumour coverage) | AUPRC (SNV only, tumour-only, 75x tumour coverage) | F1 (SNV only, tumour-only, 25x tumour coverage, at the best-F1 threshold) | F1 (SNV only, tumour-only, 50x tumour coverage, at the best-F1 threshold) | F1 (SNV only, tumour-only, 75x tumour coverage, at the best-F1 threshold) | False negatives (SNV only, tumour-only, 25x tumour coverage, at the best-F1 threshold) | False negatives (SNV only, tumour-only, 50x tumour coverage, at the best-F1 threshold) | False negatives (SNV only, tumour-only, 75x tumour coverage, at the best-F1 threshold) | False positives (SNV only, tumour-only, 25x tumour coverage, at the best-F1 threshold) | False positives (SNV only, tumour-only, 50x tumour coverage, at the best-F1 threshold) | False positives (SNV only, tumour-only, 75x tumour coverage, at the best-F1 threshold) | Precision (SNV only, tumour-only, 25x tumour coverage, at the best-F1 threshold) | Precision (SNV only, tumour-only, 50x tumour coverage, at the best-F1 threshold) | Precision (SNV only, tumour-only, 75x tumour coverage, at the best-F1 threshold) | Recall (SNV only, tumour-only, 25x tumour coverage, at the best-F1 threshold) | Recall (SNV only, tumour-only, 50x tumour coverage, at the best-F1 threshold) | Recall (SNV only, tumour-only, 75x tumour coverage, at the best-F1 threshold) | True positives (SNV only, tumour-only, 25x tumour coverage, at the best-F1 threshold) | True positives (SNV only, tumour-only, 50x tumour coverage, at the best-F1 threshold) | True positives (SNV only, tumour-only, 75x tumour coverage, at the best-F1 threshold) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Clair3 v1.0.8, tumour-only, ONT (Chen et al. 2025)Evaluation | 0.43 | 0.48 | 0.482 | 0.594 | 0.631 | 0.634 | 12,414 | 10,560 | 10,838 | 14,673 | 14,723 | 13,824 | 0.574 | 0.595 | 0.607 | 0.615 | 0.672 | 0.663 | 19,798 | 21,652 | 21,374 |
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ONT HCC1395 tumour-only, 25x to 75x, somatic SNVs (Chen et al. 2025 Supplementary Table 2b)
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54 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation Not reported Context-only references | ClairS-TO: a deep-learning method for long-read tumor-only somatic small variant calling Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature Communications, published 2025-10-31; PMC12579226 full-text XML | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: adaptation Not reported Context-only references | ClairS-TO Source Data workbook Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Source Data file (41467_2025_64547_MOESM6_ESM.xlsx) of the published article | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: adaptation Not reported Context-only references | ClairS-TO Supplementary Information (Supplementary Tables 1-8 and command lines) Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplementary Information PDF (41467_2025_64547_MOESM1_ESM.pdf) of the published article | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Single sample per coverage level Context-only references | ClairS-TO: a deep-learning method for long-read tumor-only somatic small variant calling Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature Communications, published 2025-10-31; PMC12579226 full-text XML | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Single sample per coverage level Context-only references | ClairS-TO Source Data workbook Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Source Data file (41467_2025_64547_MOESM6_ESM.xlsx) of the published article | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Single sample per coverage level Context-only references | ClairS-TO Supplementary Information (Supplementary Tables 1-8 and command lines) Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplementary Information PDF (41467_2025_64547_MOESM1_ESM.pdf) of the published article | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | ClairS-TO: a deep-learning method for long-read tumor-only somatic small variant calling Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature Communications, published 2025-10-31; PMC12579226 full-text XML | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | ClairS-TO Source Data workbook Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Source Data file (41467_2025_64547_MOESM6_ESM.xlsx) of the published article | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | ClairS-TO Supplementary Information (Supplementary Tables 1-8 and command lines) Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplementary Information PDF (41467_2025_64547_MOESM1_ESM.pdf) of the published article | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version Not reported Context-only references | ClairS-TO: a deep-learning method for long-read tumor-only somatic small variant calling Supplementary Table 2b, rows 'Clair3' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature Communications, published 2025-10-31; PMC12579226 full-text XML | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: somatic-clairs-to-20261011-eval-clair3-ont-hcc1395-snv