Published comparison transcribed from the pinned source; not reproduced.
1 evaluation · 4 results. Different protocols are not a single leaderboard.
Protocol: Splice-altering variant classification, SPiP benchmark variant set (99,601 variants) (Fortier et al. Table 3) · Dataset: SPiP benchmark variant set (99,601 variants)
Sorted by Balanced accuracy (maximum delta score > 0.5 (Legacy Ensemble N > 1)) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Balanced accuracy (maximum delta score > 0.5 (Legacy Ensemble N > 1)) | F1 (maximum delta score > 0.5 (Legacy Ensemble N > 1)) | Recall (maximum delta score > 0.5 (Legacy Ensemble N > 1)) | Specificity (maximum delta score > 0.5 (Legacy Ensemble N > 1)) |
|---|---|---|---|---|
| OpenSpliceAI (Fortier et al. 2026)Evaluation | 0.797 | 0.724 | 0.595 | 0.999 |
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18 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation maximum delta score > 0.5 (Legacy Ensemble N > 1) Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: aggregation Whole dataset Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: budget Not reported Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | missing or unspecified No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: dataset version As assembled by Fortier et al. 2026 Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: inputs Variant with genomic sequence context (VCF) Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: metric implementation Sensitivity, specificity, F1 = 2TP/(2TP+FP+FN), balanced accuracy = mean of sensitivity and specificity (Equations 1 to 4) Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: population 4,616 experimentally characterised variants from 227 genes (1,924 spliceogenic by RT-PCR, Sanger sequencing of RT-PCR products or minigene assays) plus 95,000 common control variants (MAF > 5%) from Leman et al.; 15 variants excluded on conversion to GRCh38, leaving 99,601; about 2% spliceogenic Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: protocol id rna-splicing-20261011-fortier2026-protocol-spip Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Comparison: split Whole set Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Origin independent_paper Context-only references | Analyzing the performance of deep learning splice prediction algorithms (Fortier, Rudy and Scherer, PLOS One 2026) Table 3 row 'OpenSpliceAI' Version: PLOS One 21(5):e0348885, published 2026-05-13; PMC13170886 full-text XML | not individually reviewed No individual claim review recorded independent paper Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: rna-splicing-20261011-fortier2026-eval-spip-openspliceai