| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.562 auroc unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell S29, row 'CLARK', column 'AUC' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 23.7 regression-intercept unitless · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell Y29, row 'CLARK', column 'LR intercept' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.0903% pearson-r-squared percent · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell Z29, row 'CLARK', column 'LR r2, %' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.538 regression-slope unitless · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell X29, row 'CLARK', column 'LR slope' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.973 negative-predictive-value fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell W29, row 'CLARK', column 'NPV (ROC)' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.75 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell V29, row 'CLARK', column 'PPV (ROC)' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.875 roc-distance unitless · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell R29, row 'CLARK', column 'Informedness' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.125 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell T29, row 'CLARK', column 'SN (ROC)' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 0.999 specificity fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell U29, row 'CLARK', column 'SL (ROC)' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 17 count count · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell AA29, row 'CLARK', column 'Taxa' |
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| Configuration: CLARK, human reads removed, and assigned read counts normalised by target genome length (Carbo et al. 2022) | Protocol: Respiratory virus detection against PCR, species level, read-count cut-off 10 (Carbo et al. 2022 Supplementary Table 1) Dataset: Nasal washings from COPD patients with respiratory complaints, metagenomic sequencing and 13-target respiratory PCR panel (Carbo et al. 2022) | 17 count count · unknown Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceCLARK, human reads removed, and assigned read counts normalised by target genome length: species level, read-count cut-off 10 (Carbo et al. 2022) rna-pathogen-20261009-protocol-carbo2022-species-cutoff-10 Aggregation: Not reported Carbo et al. medRxiv preprint v1, Supplementary Tables 1 and 2 · Supplementary Table 1 sheet 'Suppl table 1-Species', block 'excl. human reads and normalized', cell AB29, row 'CLARK', column 'Taxa with reads >10' |
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