Evaluation

Genion on simulated long-read fusions (Dorney et al. 2026)

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Evaluation results

1 evaluation · 35 results. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.143 F1 (simulated fusions, 100GB depth, 85% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '85%', Algorithm 'Genion', column 'F1'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	196 False positives (simulated fusions, 100GB depth, 85% mean read identity, denominator 400) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '85%', Algorithm 'Genion', column 'False_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.19 Precision (simulated fusions, 100GB depth, 85% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '85%', Algorithm 'Genion', column 'Precision'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.115 Recall (simulated fusions, 100GB depth, 85% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '85%', Algorithm 'Genion', column 'Recall'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	46 True positives (simulated fusions, 100GB depth, 85% mean read identity, denominator 400) count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '85%', Algorithm 'Genion', column 'True_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.17 F1 (simulated fusions, 100GB depth, 90% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '90%', Algorithm 'Genion', column 'F1'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	225 False positives (simulated fusions, 100GB depth, 90% mean read identity, denominator 400) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '90%', Algorithm 'Genion', column 'False_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.205 Precision (simulated fusions, 100GB depth, 90% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '90%', Algorithm 'Genion', column 'Precision'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.145 Recall (simulated fusions, 100GB depth, 90% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '90%', Algorithm 'Genion', column 'Recall'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	58 True positives (simulated fusions, 100GB depth, 90% mean read identity, denominator 400) count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '90%', Algorithm 'Genion', column 'True_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.2 F1 (simulated fusions, 100GB depth, 95% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '95%', Algorithm 'Genion', column 'F1'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	202 False positives (simulated fusions, 100GB depth, 95% mean read identity, denominator 400) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '95%', Algorithm 'Genion', column 'False_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.249 Precision (simulated fusions, 100GB depth, 95% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '95%', Algorithm 'Genion', column 'Precision'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.168 Recall (simulated fusions, 100GB depth, 95% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '95%', Algorithm 'Genion', column 'Recall'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	67 True positives (simulated fusions, 100GB depth, 95% mean read identity, denominator 400) count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '100GB', Sequence_Identity '95%', Algorithm 'Genion', column 'True_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.0098 F1 (simulated fusions, 10GB depth, 85% mean read identity, denominator 397) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '85%', Algorithm 'Genion', column 'F1'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	9 False positives (simulated fusions, 10GB depth, 85% mean read identity, denominator 397) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '85%', Algorithm 'Genion', column 'False_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.182 Precision (simulated fusions, 10GB depth, 85% mean read identity, denominator 397) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '85%', Algorithm 'Genion', column 'Precision'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.00504 Recall (simulated fusions, 10GB depth, 85% mean read identity, denominator 397) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '85%', Algorithm 'Genion', column 'Recall'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	2 True positives (simulated fusions, 10GB depth, 85% mean read identity, denominator 397) count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '85%', Algorithm 'Genion', column 'True_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.0194 F1 (simulated fusions, 10GB depth, 90% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '90%', Algorithm 'Genion', column 'F1'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	8 False positives (simulated fusions, 10GB depth, 90% mean read identity, denominator 400) count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '90%', Algorithm 'Genion', column 'False_Point'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.333 Precision (simulated fusions, 10GB depth, 90% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '90%', Algorithm 'Genion', column 'Precision'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	0.01 Recall (simulated fusions, 10GB depth, 90% mean read identity, denominator 400) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '90%', Algorithm 'Genion', column 'Recall'
Configuration: Genion v1.1.0 (Dorney et al. 2026)	Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026) Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)	4 True positives (simulated fusions, 10GB depth, 90% mean read identity, denominator 400) count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Independent external evaluation · Source checked Methods, coverage and source Genion on simulated long-read fusions (Dorney et al. 2026) rna-fusion-longread-20261011-protocol-simulated-fusions Aggregation: Not reported A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing; LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · stat_summary.tsv, row depth '10GB', Sequence_Identity '90%', Algorithm 'Genion', column 'True_Point'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

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Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

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Evaluation procedure

Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026)

Configuration: Genion v1.1.0 (Dorney et al. 2026)
Protocol: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026)
Dataset: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)

origin: Independent external evaluation
configuration: Primary source as retrieved 2026-10-11
protocol id: rna-fusion-longread-20261011-protocol-simulated-fusions
dataset version: Not reported
split: Simulation
population: 400 simulated fusions per scenario
inputs: Simulated ONT reads aligned with minimap2
adaptation: Not reported
metric implementation: Partner-gene match; partial recalls counted as false positives; at least two supporting reads
aggregation: One run per scenario
budget: Not reported

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split: Simulation
Adaptation: Not reported
Scoring implementation: Partner-gene match; partial recalls counted as false positives; at least two supporting reads

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Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

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Evidence table

Inspect claims, sources and review details

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One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

36 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Comparison: adaptation Not reported Context-only references	A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv preprint version 1, posted 2026-08-12; JATS XML Retrieved: 2026-10-11T21:36:20Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.adaptation` Source artifact SHA-256: `c665bb407799324bc50ae1792d82574a41ae4a9182befd360973d89a82cbaa5b` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: adaptation Not reported Context-only references	LRFusionBenchmark repository (Dorney et al.): result tables and run scripts Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Git commit 83e629fed3098881079fd9ac1c8bc13478ce69ed (pushed 2026-08-25); files: Figures/Input_dataframes/stat_summary.tsv, Figures/Input_dataframes/counts_SGNex_summary.tsv.gz, Fusions/runtools/Run_GFSLGF.sh, Fusions/runtools/RunJAFFAL.sh, Fusions/runtools/RunCTAT-LR-fusion.sh, Fusions/runtools/RunGFSeeker.sh, SimulatedData/Data_Analysis_Scripts/Precision_Recall_ReadSupp_stats.R, CellLineData/SGNex_DiscoveryNRecall.R Retrieved: 2026-10-11T21:48:03Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.adaptation` Source artifact SHA-256: `c2fa853553979a11b8cb665cf3d195cbe64530c755054f5768d05ab6ba46d17e` Hash scope: SHA-256 of a JSON bundle listing each retrieved file with its path, its own SHA-256 and its content (gzipped files decompressed); archived as artifacts/lrfusionbenchmark-bundle.json.gz Inspected artifact
Comparison: aggregation One run per scenario Context-only references	A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv preprint version 1, posted 2026-08-12; JATS XML Retrieved: 2026-10-11T21:36:20Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.aggregation` Source artifact SHA-256: `c665bb407799324bc50ae1792d82574a41ae4a9182befd360973d89a82cbaa5b` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: aggregation One run per scenario Context-only references	LRFusionBenchmark repository (Dorney et al.): result tables and run scripts Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Git commit 83e629fed3098881079fd9ac1c8bc13478ce69ed (pushed 2026-08-25); files: Figures/Input_dataframes/stat_summary.tsv, Figures/Input_dataframes/counts_SGNex_summary.tsv.gz, Fusions/runtools/Run_GFSLGF.sh, Fusions/runtools/RunJAFFAL.sh, Fusions/runtools/RunCTAT-LR-fusion.sh, Fusions/runtools/RunGFSeeker.sh, SimulatedData/Data_Analysis_Scripts/Precision_Recall_ReadSupp_stats.R, CellLineData/SGNex_DiscoveryNRecall.R Retrieved: 2026-10-11T21:48:03Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.aggregation` Source artifact SHA-256: `c2fa853553979a11b8cb665cf3d195cbe64530c755054f5768d05ab6ba46d17e` Hash scope: SHA-256 of a JSON bundle listing each retrieved file with its path, its own SHA-256 and its content (gzipped files decompressed); archived as artifacts/lrfusionbenchmark-bundle.json.gz Inspected artifact
Comparison: budget Not reported Context-only references	A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv preprint version 1, posted 2026-08-12; JATS XML Retrieved: 2026-10-11T21:36:20Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.budget` Source artifact SHA-256: `c665bb407799324bc50ae1792d82574a41ae4a9182befd360973d89a82cbaa5b` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: budget Not reported Context-only references	LRFusionBenchmark repository (Dorney et al.): result tables and run scripts Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Git commit 83e629fed3098881079fd9ac1c8bc13478ce69ed (pushed 2026-08-25); files: Figures/Input_dataframes/stat_summary.tsv, Figures/Input_dataframes/counts_SGNex_summary.tsv.gz, Fusions/runtools/Run_GFSLGF.sh, Fusions/runtools/RunJAFFAL.sh, Fusions/runtools/RunCTAT-LR-fusion.sh, Fusions/runtools/RunGFSeeker.sh, SimulatedData/Data_Analysis_Scripts/Precision_Recall_ReadSupp_stats.R, CellLineData/SGNex_DiscoveryNRecall.R Retrieved: 2026-10-11T21:48:03Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.budget` Source artifact SHA-256: `c2fa853553979a11b8cb665cf3d195cbe64530c755054f5768d05ab6ba46d17e` Hash scope: SHA-256 of a JSON bundle listing each retrieved file with its path, its own SHA-256 and its content (gzipped files decompressed); archived as artifacts/lrfusionbenchmark-bundle.json.gz Inspected artifact
Comparison: dataset version Not reported Context-only references	A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv preprint version 1, posted 2026-08-12; JATS XML Retrieved: 2026-10-11T21:36:20Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.dataset_version` Source artifact SHA-256: `c665bb407799324bc50ae1792d82574a41ae4a9182befd360973d89a82cbaa5b` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: dataset version Not reported Context-only references	LRFusionBenchmark repository (Dorney et al.): result tables and run scripts Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Git commit 83e629fed3098881079fd9ac1c8bc13478ce69ed (pushed 2026-08-25); files: Figures/Input_dataframes/stat_summary.tsv, Figures/Input_dataframes/counts_SGNex_summary.tsv.gz, Fusions/runtools/Run_GFSLGF.sh, Fusions/runtools/RunJAFFAL.sh, Fusions/runtools/RunCTAT-LR-fusion.sh, Fusions/runtools/RunGFSeeker.sh, SimulatedData/Data_Analysis_Scripts/Precision_Recall_ReadSupp_stats.R, CellLineData/SGNex_DiscoveryNRecall.R Retrieved: 2026-10-11T21:48:03Z	missing or unspecified No individual claim review recorded independent paper Audit details Field: `attributes.comparison.dataset_version` Source artifact SHA-256: `c2fa853553979a11b8cb665cf3d195cbe64530c755054f5768d05ab6ba46d17e` Hash scope: SHA-256 of a JSON bundle listing each retrieved file with its path, its own SHA-256 and its content (gzipped files decompressed); archived as artifacts/lrfusionbenchmark-bundle.json.gz Inspected artifact
Comparison: inputs Simulated ONT reads aligned with minimap2 Context-only references	A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv preprint version 1, posted 2026-08-12; JATS XML Retrieved: 2026-10-11T21:36:20Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.inputs` Source artifact SHA-256: `c665bb407799324bc50ae1792d82574a41ae4a9182befd360973d89a82cbaa5b` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: inputs Simulated ONT reads aligned with minimap2 Context-only references	LRFusionBenchmark repository (Dorney et al.): result tables and run scripts Original source ↗ stat_summary.tsv, rows Algorithm 'Genion' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Git commit 83e629fed3098881079fd9ac1c8bc13478ce69ed (pushed 2026-08-25); files: Figures/Input_dataframes/stat_summary.tsv, Figures/Input_dataframes/counts_SGNex_summary.tsv.gz, Fusions/runtools/Run_GFSLGF.sh, Fusions/runtools/RunJAFFAL.sh, Fusions/runtools/RunCTAT-LR-fusion.sh, Fusions/runtools/RunGFSeeker.sh, SimulatedData/Data_Analysis_Scripts/Precision_Recall_ReadSupp_stats.R, CellLineData/SGNex_DiscoveryNRecall.R Retrieved: 2026-10-11T21:48:03Z	not individually reviewed No individual claim review recorded independent paper Audit details Field: `attributes.comparison.inputs` Source artifact SHA-256: `c2fa853553979a11b8cb665cf3d195cbe64530c755054f5768d05ab6ba46d17e` Hash scope: SHA-256 of a JSON bundle listing each retrieved file with its path, its own SHA-256 and its content (gzipped files decompressed); archived as artifacts/lrfusionbenchmark-bundle.json.gz Inspected artifact

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Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

2 source records and release history

A comprehensive benchmark of transcriptome-wide fusion detection using long-read RNA sequencing · Original source · bioRxiv preprint version 1, posted 2026-08-12; JATS XML
LRFusionBenchmark repository (Dorney et al.): result tables and run scripts · Original source · Git commit 83e629fed3098881079fd9ac1c8bc13478ce69ed (pushed 2026-08-25); files: Figures/Input_dataframes/stat_summary.tsv, Figures/Input_dataframes/counts_SGNex_summary.tsv.gz, Fusions/runtools/Run_GFSLGF.sh, Fusions/runtools/RunJAFFAL.sh, Fusions/runtools/RunCTAT-LR-fusion.sh, Fusions/runtools/RunGFSeeker.sh, SimulatedData/Data_Analysis_Scripts/Precision_Recall_ReadSupp_stats.R, CellLineData/SGNex_DiscoveryNRecall.R

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Technical metadata and extraction receipts

Stable ID: rna-fusion-longread-20261011-eval-genion-simulated-fusions

areas: rna-transcriptomes
contexts: clinical_research
origin: independent_paper
protocol: rna-fusion-longread-20261011-protocol-simulated-fusions
version: Primary source as retrieved 2026-10-11
comparison: protocol id: rna-fusion-longread-20261011-protocol-simulated-fusions; dataset version: Not reported; split: Simulation; population: 400 simulated fusions per scenario; inputs: Simulated ONT reads aligned with minimap2; adaptation: Not reported; metric implementation: Partner-gene match; partial recalls counted as false positives; at least two supporting reads; aggregation: One run per scenario; budget: Not reported
source locator: stat_summary.tsv, rows Algorithm 'Genion'
missing metadata: comparison.adaptation: reason: inapplicable; note: No training; comparison.budget: reason: unreported; comparison.dataset version: reason: unreported

Related records

system: Genion v1.1.0 (Dorney et al. 2026)
assessment: Simulated long-read fusion detection, 400 fusions at three depths and three read identities (Dorney et al. 2026)
data: Badread simulated ONT transcriptomes with 400 Fusim fusion transcripts (Dorney et al. 2026)
evaluation: Genion simulated 100GB 85% f1-score
evaluation: Genion simulated 100GB 85% false-positive-count
evaluation: Genion simulated 100GB 85% precision
evaluation: Genion simulated 100GB 85% recall
evaluation: Genion simulated 100GB 85% true-positive-count
evaluation: Genion simulated 100GB 90% f1-score
evaluation: Genion simulated 100GB 90% false-positive-count
evaluation: Genion simulated 100GB 90% precision
evaluation: Genion simulated 100GB 90% recall
evaluation: Genion simulated 100GB 90% true-positive-count
evaluation: Genion simulated 100GB 95% f1-score
evaluation: Genion simulated 100GB 95% false-positive-count
evaluation: Genion simulated 100GB 95% precision
evaluation: Genion simulated 100GB 95% recall
evaluation: Genion simulated 100GB 95% true-positive-count
evaluation: Genion simulated 10GB 85% f1-score
evaluation: Genion simulated 10GB 85% false-positive-count
evaluation: Genion simulated 10GB 85% precision
evaluation: Genion simulated 10GB 85% recall
evaluation: Genion simulated 10GB 85% true-positive-count
evaluation: Genion simulated 10GB 90% f1-score
evaluation: Genion simulated 10GB 90% false-positive-count
evaluation: Genion simulated 10GB 90% precision
evaluation: Genion simulated 10GB 90% recall
evaluation: Genion simulated 10GB 90% true-positive-count
evaluation: Genion simulated 10GB 95% f1-score
evaluation: Genion simulated 10GB 95% false-positive-count
evaluation: Genion simulated 10GB 95% precision
evaluation: Genion simulated 10GB 95% recall
evaluation: Genion simulated 10GB 95% true-positive-count
evaluation: Genion simulated 1GB 85% f1-score
evaluation: Genion simulated 1GB 85% false-positive-count
evaluation: Genion simulated 1GB 85% precision
evaluation: Genion simulated 1GB 85% recall
evaluation: Genion simulated 1GB 85% true-positive-count

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