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Evaluation

Decoder on PerturBench CB-COSINE: combination prediction on Norman19, Cosine similarity of log fold change

PerturBench evaluation of Decoder on combination prediction on Norman19, Cosine similarity of log fold change, scored with Cosine similarity of log fold change.

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Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

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Evaluation results

1 evaluation · 1 result. Different protocols are not a single leaderboard.

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Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: DecoderTask: PerturBench CB-COSINE: combination prediction on Norman19, Cosine similarity of log fold change
Dataset subset: Norman19 (PerturBench split)
0.73 ± 2 × 10 − 2 cosine_logfc
fraction · higher

Uncertainty: type: standard_deviation; value: 0.02

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Decoder on PerturBench CB-COSINE: combination prediction on Norman19, Cosine similarity of log fold change

Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.

Aggregation: Not reported

PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis · Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Evaluation procedure

Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.

Configuration
Decoder
Task
PerturBench CB-COSINE: combination prediction on Norman19, Cosine similarity of log fold change
Dataset subset
Norman19 (PerturBench split)
origin
Author-reported evaluation
configuration
Not reported
protocol id
perturbench-task-cb-cosine
metric implementation
Cosine similarity of log fold change

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Not reported
Adaptation
Not reported
Scoring implementation
Cosine similarity of log fold change

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

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Evidence table

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10 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
attributes.comparison.metric_implementation
Cosine similarity of log fold change
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.comparison.protocol_id
perturbench-task-cb-cosine
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.origin
author_reported
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.origin

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.protocol
Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.protocol

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.source_locator
Table 3, row(Decoder), column(Cosine, log fold change (LogFC))
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

description
PerturBench evaluation of Decoder on combination prediction on Norman19, Cosine similarity of log fold change, scored with Cosine similarity of log fold change.
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: description

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Relationship: benchmark
perturbench-task-cb-cosine
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: links:benchmark:perturbench-task-cb-cosine

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Relationship: dataset
perturbench-dataset-norman19
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: links:dataset:perturbench-dataset-norman19

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Relationship: model
perturbench-method-decoder
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: links:model:perturbench-method-decoder

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

name
Decoder on PerturBench CB-COSINE: combination prediction on Norman19, Cosine similarity of log fold change
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(Decoder), column(Cosine, log fold change (LogFC))

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: name

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-29-06401fd5b220 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: perturbench-evaluation-decoder-cb-cosine

areas
cells-tissues
tasks
combination prediction on Norman19, Cosine similarity of log fold change
origin
author_reported
protocol
Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.
comparison
protocol id: perturbench-task-cb-cosine; metric implementation: Cosine similarity of log fold change
missing metadata
checkpoint revision: unreported; seeds: unreported; budget: unreported; split manifest: unextracted
source locator
Table 3, row(Decoder), column(Cosine, log fold change (LogFC))
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