rewirebio.iobenchmarks
Evaluation

CPA* (noAdv) on PerturBench CB-RMSE-RANK: combination prediction on Norman19, RMSE mean rank

PerturBench evaluation of CPA* (noAdv) on combination prediction on Norman19, RMSE mean rank, scored with RMSE mean rank.

Evaluation results

1 evaluation · 1 result. Different protocols are not a single leaderboard.

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Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: CPA* (noAdv)Task: PerturBench CB-RMSE-RANK: combination prediction on Norman19, RMSE mean rank
Dataset subset: Norman19 (PerturBench split)
0.18 ± 2 × 10 − 2 Perturbench RMSE rank
fraction · lower

Uncertainty: SD 0.02

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

CPA* (noAdv) on PerturBench CB-RMSE-RANK: combination prediction on Norman19, RMSE mean rank

Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.

Aggregation: Not reported

PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis · Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-11-02-a7f03c9e55a5 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
  • Compute requirements are estimated: not yet verified

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Evaluation procedure

Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.

Configuration
CPA* (noAdv)
Task
PerturBench CB-RMSE-RANK: combination prediction on Norman19, RMSE mean rank
Dataset subset
Norman19 (PerturBench split)
origin
Author-reported evaluation
configuration
Not reported
protocol id
perturbench-task-cb-rmse-rank
metric implementation
RMSE mean rank

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Not reported
Adaptation
Not reported
Scoring implementation
RMSE mean rank

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

10 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Comparison: metric implementation
RMSE mean rank
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Comparison: protocol id
perturbench-task-cb-rmse-rank
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Origin
author_reported
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.origin

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Protocol
Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.protocol

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Source location
Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Description
PerturBench evaluation of CPA* (noAdv) on combination prediction on Norman19, RMSE mean rank, scored with RMSE mean rank.
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: description

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Relationship: assessment
perturbench-task-cb-rmse-rank
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: links:assessment:perturbench-task-cb-rmse-rank

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Relationship: data
perturbench-dataset-norman19
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: links:data:perturbench-dataset-norman19

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Relationship: system
perturbench-method-cpa-noadv
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: links:system:perturbench-method-cpa-noadv

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Name
CPA* (noAdv) on PerturBench CB-RMSE-RANK: combination prediction on Norman19, RMSE mean rank
Context-only references
PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis

Original source ↗

Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)

Version: Primary full-text snapshot retrieved 2026-09-17; exact bytes pinned by SHA-256
Retrieved: 2026-09-17T08:06:28.400469+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: name

Source artifact SHA-256: 5c4804565dd9faa17a11853a79e9847dcb6da73715b4c91f62e5b274cc79f186

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: perturbench-evaluation-cpa-noadv-cb-rmse-rank

areas
cells-tissues
tasks
combination prediction on Norman19, RMSE mean rank
origin
author_reported
protocol
Predict the effect of a pair of gene overexpressions from single perturbations, reported as the mean and one standard deviation over seeds.
comparison
protocol id: perturbench-task-cb-rmse-rank; metric implementation: RMSE mean rank
missing metadata
budget: reason: unreported; checkpoint revision: reason: unreported; seeds: reason: unreported; split manifest: reason: unextracted
source locator
Table 3, row(CPA ∗ (noAdv)), column(RMSE, mean rank)
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