Evaluation

Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026)

Evidence concern: excluded from comparisons

Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2

Published execution benchmark; transcribed, not reproduced.

Evaluation results

1 evaluation · 20 results. Different protocols are not a single leaderboard.

Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) · Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x

Sorted by Data io volume (Variant calling from BAM, whole run; HG003 PacBio 10x) (lower is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Data io volume (Variant calling from BAM, whole run; HG003 PacBio 10x)	Data io volume (Variant calling from BAM, whole run; HG003 PacBio 20x)	Data io volume (Variant calling from BAM, whole run; HG003 PacBio 30x)	Data io volume (Variant calling from BAM, whole run; HG003 PacBio 40x)	Data io volume (Variant calling from BAM, whole run; HG003 PacBio 50x)	Mean memory (Variant calling from BAM, whole run; HG003 PacBio 10x)	Mean memory (Variant calling from BAM, whole run; HG003 PacBio 20x)	Mean memory (Variant calling from BAM, whole run; HG003 PacBio 30x)	Mean memory (Variant calling from BAM, whole run; HG003 PacBio 40x)	Mean memory (Variant calling from BAM, whole run; HG003 PacBio 50x)	Peak memory (Variant calling from BAM, whole run; HG003 PacBio 10x)	Peak memory (Variant calling from BAM, whole run; HG003 PacBio 20x)	Peak memory (Variant calling from BAM, whole run; HG003 PacBio 30x)	Peak memory (Variant calling from BAM, whole run; HG003 PacBio 40x)	Peak memory (Variant calling from BAM, whole run; HG003 PacBio 50x)	Runtime (Variant calling from BAM, whole run; HG003 PacBio 10x)	Runtime (Variant calling from BAM, whole run; HG003 PacBio 20x)	Runtime (Variant calling from BAM, whole run; HG003 PacBio 30x)	Runtime (Variant calling from BAM, whole run; HG003 PacBio 40x)	Runtime (Variant calling from BAM, whole run; HG003 PacBio 50x)
Clair3 v1.2.0 GPU mode (Zheng et al. 2026)Evaluation	88	98	128	125	139	6,781	5,758	8,034	7,985	5,489	41,832	52,578	49,319	46,024	55,095	14	13	12	12	12

All 20 result rows with coverage, uncertainty and sources

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	88 Data io volume (Variant calling from BAM, whole run; HG003 PacBio 10x) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 10x, column 'Total data movement IO (GB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	6,781 Mean memory (Variant calling from BAM, whole run; HG003 PacBio 10x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 10x, column 'Average memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	41,832 Peak memory (Variant calling from BAM, whole run; HG003 PacBio 10x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 10x, column 'Peak memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	14 Runtime (Variant calling from BAM, whole run; HG003 PacBio 10x) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 10x, column 'Runtime (minutes)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	98 Data io volume (Variant calling from BAM, whole run; HG003 PacBio 20x) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 20x, column 'Total data movement IO (GB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	5,758 Mean memory (Variant calling from BAM, whole run; HG003 PacBio 20x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 20x, column 'Average memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	52,578 Peak memory (Variant calling from BAM, whole run; HG003 PacBio 20x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 20x, column 'Peak memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	13 Runtime (Variant calling from BAM, whole run; HG003 PacBio 20x) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 20x, column 'Runtime (minutes)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	128 Data io volume (Variant calling from BAM, whole run; HG003 PacBio 30x) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 30x, column 'Total data movement IO (GB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	8,034 Mean memory (Variant calling from BAM, whole run; HG003 PacBio 30x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 30x, column 'Average memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	49,319 Peak memory (Variant calling from BAM, whole run; HG003 PacBio 30x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 30x, column 'Peak memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	12 Runtime (Variant calling from BAM, whole run; HG003 PacBio 30x) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 30x, column 'Runtime (minutes)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	125 Data io volume (Variant calling from BAM, whole run; HG003 PacBio 40x) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 40x, column 'Total data movement IO (GB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	7,985 Mean memory (Variant calling from BAM, whole run; HG003 PacBio 40x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 40x, column 'Average memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	46,024 Peak memory (Variant calling from BAM, whole run; HG003 PacBio 40x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 40x, column 'Peak memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	12 Runtime (Variant calling from BAM, whole run; HG003 PacBio 40x) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 40x, column 'Runtime (minutes)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	139 Data io volume (Variant calling from BAM, whole run; HG003 PacBio 50x) gigabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 50x, column 'Total data movement IO (GB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	5,489 Mean memory (Variant calling from BAM, whole run; HG003 PacBio 50x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 50x, column 'Average memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	55,095 Peak memory (Variant calling from BAM, whole run; HG003 PacBio 50x) megabyte · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 50x, column 'Peak memory (MB)'
Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)	Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2) Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x	12 Runtime (Variant calling from BAM, whole run; HG003 PacBio 50x) minute · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Evidence concern: excluded from comparisons Supplementary Table 2 runtimes differ from the article's Results for what appear to be the same HG003 comparisons. ONT at 30x and 50x: Clair3 GPU 17 and 20 minutes in the table, 16 and 15 in Results 3.1.1; DeepVariant GPU 48 and 82 in the table, 106 to 128 in the text. PacBio Revio at 30x and 50x: Clair3 GPU 12 and 12 in the table, 23 and 21 in Results 3.1.2; DeepVariant GPU 40 and 53 in the table, 93 and 118 in the text. The table's Clair3 PacBio runtimes equal the macOS M3 Ultra runtime in Results 3.1.3, not the Linux RTX 4090 runtimes. The table and the Supplementary Notes commands give DeepVariant v1.10-beta; Results 3.1 say v1.8. Supplementary Table 3 DeepVariant ONT SNP precision, recall and F1 at 10x and 20x (97.58%, 92.35%, 94.89% and 99.32%, 99.02%, 99.17%) differ from Results 3.2 (97.34%, 92.17%, 94.68% and 98.75%, 98.79%, 98.79%), while the Clair3 values agree. Results 3.2 cite Supplementary Table 2 for the HG001 to HG007 comparison, which is Supplementary Table 4. The hardware, DeepVariant version and runs behind Supplementary Tables 2 and 3 are therefore uncertain. Supplementary Table 1 agrees with Results 3.1.4 except WhatsHap ONT 30x (723 seconds in the table, 724 in the text). Table values are recorded; text values are not.Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Tables 1 to 3 (pages 2 and 3) versus article Results 3.1.1 to 3.1.4 and 3.2 Methods, coverage and source Clair3 v1.2.0 (GPU mode), HG003 PacBio runtime and memory (Zheng et al. 2026) model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio Aggregation: Not reported Accelerated long-read variant calling with Clair3 for whole-genome sequencing; Accelerated long-read variant calling with Clair3: Supplementary Data · Supplementary Table 2 (image, page 2), sample 'HG003 WGS', platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)', read coverage 50x, column 'Runtime (minutes)'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

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Readiness checks, gaps and artifacts

Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

Evidence incomplete

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Evaluation procedure

HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2)

Configuration: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)
Protocol: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2)
Dataset: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x

origin: Author-reported evaluation
configuration: Primary source as retrieved 2026-10-11
protocol id: model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio
dataset version: Not reported
split: HG003 subsampled to 10x, 20x, 30x, 40x and 50x
population: One GIAB sample (HG003)
inputs: Aligned reads (BAM) and GRCh38 reference
adaptation: Not reported
metric implementation: Not reported
aggregation: One value per coverage
budget: One value per caller and coverage; number of runs and hardware not stated in the table

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split: HG003 subsampled to 10x, 20x, 30x, 40x and 50x
Adaptation: Not reported
Scoring implementation: Not reported

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Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

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Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

36 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Comparison: adaptation Not reported Context-only references	Accelerated long-read variant calling with Clair3 for whole-genome sequencing Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Bioinformatics 42(5), published 2026-04-10; PMC13141153 full-text XML Retrieved: 2026-10-11T21:42:40Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.adaptation` Source artifact SHA-256: `99ef4db5251a77e6fb9137aa3699b4dac93bdef2aff99de91c4d24ca5fc6a965` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: adaptation Not reported Context-only references	Accelerated long-read variant calling with Clair3: Supplementary Data Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: btag181_supplementary_data.pdf from the Europe PMC supplementary files of PMC13141153 Retrieved: 2026-10-11T21:42:40Z	missing or unspecified No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.comparison.adaptation` Source artifact SHA-256: `feec482c5befbb44f93b82782b200a3abebaf7d81a0aad81e28de191be1523d9` Hash scope: Hash scope not separately documented; inspect source record Archive member: btag181_supplementary_data.pdf Inspected artifact
Comparison: aggregation One value per coverage Context-only references	Accelerated long-read variant calling with Clair3 for whole-genome sequencing Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Bioinformatics 42(5), published 2026-04-10; PMC13141153 full-text XML Retrieved: 2026-10-11T21:42:40Z	not individually reviewed No individual claim review recorded author reported Audit details Field: `attributes.comparison.aggregation` Source artifact SHA-256: `99ef4db5251a77e6fb9137aa3699b4dac93bdef2aff99de91c4d24ca5fc6a965` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: aggregation One value per coverage Context-only references	Accelerated long-read variant calling with Clair3: Supplementary Data Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: btag181_supplementary_data.pdf from the Europe PMC supplementary files of PMC13141153 Retrieved: 2026-10-11T21:42:40Z	not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.comparison.aggregation` Source artifact SHA-256: `feec482c5befbb44f93b82782b200a3abebaf7d81a0aad81e28de191be1523d9` Hash scope: Hash scope not separately documented; inspect source record Archive member: btag181_supplementary_data.pdf Inspected artifact
Comparison: budget One value per caller and coverage; number of runs and hardware not stated in the table Context-only references	Accelerated long-read variant calling with Clair3 for whole-genome sequencing Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Bioinformatics 42(5), published 2026-04-10; PMC13141153 full-text XML Retrieved: 2026-10-11T21:42:40Z	not individually reviewed No individual claim review recorded author reported Audit details Field: `attributes.comparison.budget` Source artifact SHA-256: `99ef4db5251a77e6fb9137aa3699b4dac93bdef2aff99de91c4d24ca5fc6a965` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: budget One value per caller and coverage; number of runs and hardware not stated in the table Context-only references	Accelerated long-read variant calling with Clair3: Supplementary Data Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: btag181_supplementary_data.pdf from the Europe PMC supplementary files of PMC13141153 Retrieved: 2026-10-11T21:42:40Z	not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.comparison.budget` Source artifact SHA-256: `feec482c5befbb44f93b82782b200a3abebaf7d81a0aad81e28de191be1523d9` Hash scope: Hash scope not separately documented; inspect source record Archive member: btag181_supplementary_data.pdf Inspected artifact
Comparison: dataset version Not reported Context-only references	Accelerated long-read variant calling with Clair3 for whole-genome sequencing Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Bioinformatics 42(5), published 2026-04-10; PMC13141153 full-text XML Retrieved: 2026-10-11T21:42:40Z	missing or unspecified No individual claim review recorded author reported Audit details Field: `attributes.comparison.dataset_version` Source artifact SHA-256: `99ef4db5251a77e6fb9137aa3699b4dac93bdef2aff99de91c4d24ca5fc6a965` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: dataset version Not reported Context-only references	Accelerated long-read variant calling with Clair3: Supplementary Data Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: btag181_supplementary_data.pdf from the Europe PMC supplementary files of PMC13141153 Retrieved: 2026-10-11T21:42:40Z	missing or unspecified No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.comparison.dataset_version` Source artifact SHA-256: `feec482c5befbb44f93b82782b200a3abebaf7d81a0aad81e28de191be1523d9` Hash scope: Hash scope not separately documented; inspect source record Archive member: btag181_supplementary_data.pdf Inspected artifact
Comparison: inputs Aligned reads (BAM) and GRCh38 reference Context-only references	Accelerated long-read variant calling with Clair3 for whole-genome sequencing Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Bioinformatics 42(5), published 2026-04-10; PMC13141153 full-text XML Retrieved: 2026-10-11T21:42:40Z	not individually reviewed No individual claim review recorded author reported Audit details Field: `attributes.comparison.inputs` Source artifact SHA-256: `99ef4db5251a77e6fb9137aa3699b4dac93bdef2aff99de91c4d24ca5fc6a965` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Comparison: inputs Aligned reads (BAM) and GRCh38 reference Context-only references	Accelerated long-read variant calling with Clair3: Supplementary Data Original source ↗ Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)' Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: btag181_supplementary_data.pdf from the Europe PMC supplementary files of PMC13141153 Retrieved: 2026-10-11T21:42:40Z	not individually reviewed No individual claim review recorded author reported Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.comparison.inputs` Source artifact SHA-256: `feec482c5befbb44f93b82782b200a3abebaf7d81a0aad81e28de191be1523d9` Hash scope: Hash scope not separately documented; inspect source record Archive member: btag181_supplementary_data.pdf Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

2 source records and release history

Accelerated long-read variant calling with Clair3 for whole-genome sequencing · Original source · Bioinformatics 42(5), published 2026-04-10; PMC13141153 full-text XML
Accelerated long-read variant calling with Clair3: Supplementary Data · Original source · btag181_supplementary_data.pdf from the Europe PMC supplementary files of PMC13141153

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Technical metadata and extraction receipts

Stable ID: model-execution-20261011-eval-zheng2026-clair3-1-2-0-gpu-hg003-resource-pacbio

areas: dna-genomes
contexts: research
origin: author_reported
protocol: model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio
version: Primary source as retrieved 2026-10-11
comparison: protocol id: model-execution-20261011-protocol-zheng2026-hg003-resource-pacbio; dataset version: Not reported; split: HG003 subsampled to 10x, 20x, 30x, 40x and 50x; population: One GIAB sample (HG003); inputs: Aligned reads (BAM) and GRCh38 reference; adaptation: Not reported; metric implementation: Not reported; aggregation: One value per coverage; budget: One value per caller and coverage; number of runs and hardware not stated in the table
source locator: Supplementary Table 2, platform 'PacBio Revio', caller 'Clair3 v1.2.0 (GPU mode)'
missing metadata: comparison.dataset version: reason: unreported

Related records

system: Clair3 v1.2.0 GPU mode (Zheng et al. 2026)
assessment: HG003 PacBio Revio WGS variant-calling runtime, memory and I/O, Clair3 versus DeepVariant in GPU mode (Zheng et al. 2026 Supplementary Table 2)
data: GIAB HG003 whole genome, PacBio Revio (2022Q4 release), subsampled to 10x-50x
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 10x io
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 10x mean-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 10x peak-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 10x runtime
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 20x io
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 20x mean-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 20x peak-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 20x runtime
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 30x io
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 30x mean-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 30x peak-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 30x runtime
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 40x io
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 40x mean-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 40x peak-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 40x runtime
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 50x io
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 50x mean-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 50x peak-memory
evaluation: zheng2026 Clair3 v1.2.0 (GPU mode) PacBio 50x runtime

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