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Evaluation

GenomeOcean-500M FP8 (E4M3) embedding extraction (Yu et al. 2026)

Published inference benchmark; transcribed, not reproduced.

Evaluation results

1 evaluation · 4 results. Different protocols are not a single leaderboard.

Protocol: GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3) · Dataset: GTDB genome fragments for metagenomic binning, 20 of a pre-sampled pool of 50 bacterial genomes per trial (Yu et al. 2026)

Sorted by Adjusted rand index (DBSCAN clustering of embeddings against GTDB species labels) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationAdjusted rand index (DBSCAN clustering of embeddings against GTDB species labels)Inference throughput (Embedding extraction; input tokens per second)Peak memory (Embedding extraction; peak GPU memory allocated)Throughput change (Embedding extraction; relative to the BF16 baseline of the same model scale)
GenomeOcean-500M, FP8 (E4M3) static weights, PyTorch with FBGEMM (Yu et al. 2026)Evaluation0.3273 ± 0.0508204,973 ± 77746.7−11.1%
All 4 result rows with coverage, uncertainty and sources
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Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: GenomeOcean-500M, FP8 (E4M3) static weights, PyTorch with FBGEMM (Yu et al. 2026)Protocol: GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3)
Dataset: GTDB genome fragments for metagenomic binning, 20 of a pre-sampled pool of 50 bacterial genomes per trial (Yu et al. 2026)
0.3273 ± 0.0508 Adjusted rand index (DBSCAN clustering of embeddings against GTDB species labels)
unitless · higher

Uncertainty: SD 0.0508

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GenomeOcean-500M FP8 (E4M3) embedding extraction (Yu et al. 2026)

model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8

Aggregation: Not reported

FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean · Table 3, row Model '500M', Precision 'FP8 (E4M3)', column 'DBSCAN ARI'
Configuration: GenomeOcean-500M, FP8 (E4M3) static weights, PyTorch with FBGEMM (Yu et al. 2026)Protocol: GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3)
Dataset: GTDB genome fragments for metagenomic binning, 20 of a pre-sampled pool of 50 bacterial genomes per trial (Yu et al. 2026)
46.7 Peak memory (Embedding extraction; peak GPU memory allocated)
gigabyte · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GenomeOcean-500M FP8 (E4M3) embedding extraction (Yu et al. 2026)

model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8

Aggregation: Not reported

FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean · Table 3, row Model '500M', Precision 'FP8 (E4M3)', column 'Peak VRAM (GB)'
Configuration: GenomeOcean-500M, FP8 (E4M3) static weights, PyTorch with FBGEMM (Yu et al. 2026)Protocol: GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3)
Dataset: GTDB genome fragments for metagenomic binning, 20 of a pre-sampled pool of 50 bacterial genomes per trial (Yu et al. 2026)
204,973 ± 777 Inference throughput (Embedding extraction; input tokens per second)
sample-per-second · higher

Uncertainty: SD 777

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GenomeOcean-500M FP8 (E4M3) embedding extraction (Yu et al. 2026)

model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8

Aggregation: Not reported

FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean · Table 3, row Model '500M', Precision 'FP8 (E4M3)', column 'Throughput (tok/s)'
Configuration: GenomeOcean-500M, FP8 (E4M3) static weights, PyTorch with FBGEMM (Yu et al. 2026)Protocol: GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3)
Dataset: GTDB genome fragments for metagenomic binning, 20 of a pre-sampled pool of 50 bacterial genomes per trial (Yu et al. 2026)
−11.1% Throughput change (Embedding extraction; relative to the BF16 baseline of the same model scale)
percent · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

GenomeOcean-500M FP8 (E4M3) embedding extraction (Yu et al. 2026)

model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8

Aggregation: Not reported

FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean · Table 3, row Model '500M', Precision 'FP8 (E4M3)', column 'Change'

Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.

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Release 2026-10-22-1b7cf027e4f6 · Evidence verified: Not verified

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  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

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  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

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Run locally

A pinned recipe describes the inputs, environment and resource requirements.

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Verified: Not verified

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Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

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  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
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  • Overlap with training data is checked: not yet verified

Verified: Not verified

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Evaluation procedure

GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3)

Configuration
GenomeOcean-500M, FP8 (E4M3) static weights, PyTorch with FBGEMM (Yu et al. 2026)
Protocol
GenomeOcean embedding extraction throughput, peak VRAM and binning fidelity, BF16 versus FP8 weights (Yu et al. 2026 Table 3)
Dataset
GTDB genome fragments for metagenomic binning, 20 of a pre-sampled pool of 50 bacterial genomes per trial (Yu et al. 2026)
origin
Author-reported evaluation
configuration
Primary source as retrieved 2026-10-11
protocol id
model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8
dataset version
Not reported
split
Five trials, seeds 42-46
population
GTDB bacterial genomes
inputs
Tokenized DNA sequence
adaptation
None (pretrained checkpoint, post-training quantization only)
metric implementation
Not reported
aggregation
Mean and standard deviation over five trials
budget
One NVIDIA H100 SXM5 80 GB GPU

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Five trials, seeds 42-46
Adaptation
None (pretrained checkpoint, post-training quantization only)
Scoring implementation
Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

18 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Comparison: adaptation
None (pretrained checkpoint, post-training quantization only)
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: aggregation
Mean and standard deviation over five trials
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: budget
One NVIDIA H100 SXM5 80 GB GPU
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: dataset version
Not reported
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: inputs
Tokenized DNA sequence
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: metric implementation
Not reported
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: population
GTDB bacterial genomes
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: protocol id
model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Comparison: split
Five trials, seeds 42-46
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

Origin
author_reported
Context-only references
FP8 Inference in Genomic Foundation Models: Theoretical vs. Realized Speedups on GenomeOcean

Original source ↗

Table 3 row '500M FP8 (E4M3)'

Version: bioRxiv preprint version 1, posted 2026-08-14 (PDF footer); bioRxiv API date 2026-08-18
Retrieved: 2026-10-11T21:42:49Z

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.origin

Source artifact SHA-256: ca54817d1f1a308f09bd3022e56cf6f8b86a875b110da0a38fe31236e39ca076

Hash scope: bioRxiv stamps each PDF download, so artifact_sha256 describes one retrieval (a second download differed in 40 bytes). The pdftotext -layout text layer (poppler) of both downloads has SHA-256 bec6e695ce46c4ebd6692e01a1a93167e212dffbb97b6558f1da88b1eb453501.

Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: model-execution-20261011-eval-yu2026-genomeocean-500m-fp8-weights-embedding

areas
dna-genomes
contexts
research
origin
author_reported
protocol
model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8
version
Primary source as retrieved 2026-10-11
comparison
protocol id: model-execution-20261011-protocol-yu2026-genomeocean-embedding-fp8; dataset version: Not reported; split: Five trials, seeds 42-46; population: GTDB bacterial genomes; inputs: Tokenized DNA sequence; adaptation: None (pretrained checkpoint, post-training quantization only); metric implementation: Not reported; aggregation: Mean and standard deviation over five trials; budget: One NVIDIA H100 SXM5 80 GB GPU
source locator
Table 3 row '500M FP8 (E4M3)'
missing metadata
comparison.dataset version: reason: unreported; comparison.metric implementation: reason: unreported; note: Batch sizes not printed
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