rewirebio.iobenchmarks
Evaluation

DeepVariant on Parabricks 3.7.0-1, 2 A100 GPUs on NVIDIA DGX A100 (O'Connell et al. 2023)

Published pipeline execution benchmark; transcribed, not reproduced.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-09-8cc1db47c7f9 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 2 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Parabricks 3.7.0-1, 2 A100 GPUs on NVIDIA DGX A100 (O'Connell et al. 2023)Protocol: DeepVariant execution on CPU and GPU cloud and DGX machines (O'Connell et al. 2023 Table 1)
Dataset: HG002 (GIAB) WGS FASTQ down-sampled to 30x, precisionFDA Truth Challenge V2
87.9 runtime
minute · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DeepVariant on Parabricks 3.7.0-1, 2 A100 GPUs on NVIDIA DGX A100 (O'Connell et al. 2023)

model-execution-20261009-protocol-oconnell2023-deepvariant

Aggregation: Not reported

Accelerating genomic workflows using NVIDIA Parabricks · Table 1, row 9 (DGX, GPU2, DeepVariant), column 'Time (min)'
Configuration: Parabricks 3.7.0-1, 2 A100 GPUs on NVIDIA DGX A100 (O'Connell et al. 2023)Protocol: DeepVariant execution on CPU and GPU cloud and DGX machines (O'Connell et al. 2023 Table 1)
Dataset: HG002 (GIAB) WGS FASTQ down-sampled to 30x, precisionFDA Truth Challenge V2
1.47 runtime
hour · lower

Uncertainty: Not reported by the source: Single recorded run per cell; no repeats or intervals printed

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DeepVariant on Parabricks 3.7.0-1, 2 A100 GPUs on NVIDIA DGX A100 (O'Connell et al. 2023)

model-execution-20261009-protocol-oconnell2023-deepvariant

Aggregation: Not reported

Accelerating genomic workflows using NVIDIA Parabricks · Table 1, row 9 (DGX, GPU2, DeepVariant), column 'Time (h)'

Source checking is not independent reproduction. Release 2026-10-09-8cc1db47c7f9.

Evaluation procedure

model-execution-20261009-protocol-oconnell2023-deepvariant

Configuration
Parabricks 3.7.0-1, 2 A100 GPUs on NVIDIA DGX A100 (O'Connell et al. 2023)
Protocol
DeepVariant execution on CPU and GPU cloud and DGX machines (O'Connell et al. 2023 Table 1)
Dataset
HG002 (GIAB) WGS FASTQ down-sampled to 30x, precisionFDA Truth Challenge V2
origin
Independent external evaluation
configuration
Primary source as retrieved 2026-10-09
protocol id
model-execution-20261009-protocol-oconnell2023-deepvariant
dataset version
Not reported
split
Single sample
population
HG002 30x
inputs
FASTQ
adaptation
Not reported
metric implementation
Workflow wall-clock; cost from on-demand hourly price
aggregation
Single run
budget
One recorded run per machine; no fixed hardware budget, machine type is part of each configuration (Table 1 VM-type)

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Single sample
Adaptation
Not reported
Scoring implementation
Workflow wall-clock; cost from on-demand hourly price

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

18 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-8cc1db47c7f9
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Not reported
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
Single run
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
One recorded run per machine; no fixed hardware budget, machine type is part of each configuration (Table 1 VM-type)
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
FASTQ
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Workflow wall-clock; cost from on-demand hourly price
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.population
HG002 30x
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
model-execution-20261009-protocol-oconnell2023-deepvariant
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.split
Single sample
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
independent_paper
Context-only references
Accelerating genomic workflows using NVIDIA Parabricks

Original source ↗

Table 1, row 9 (DGX, GPU2, DeepVariant)

Version: BMC Bioinformatics 24:221, published 2023-05-31; PMC10230726 full-text XML
Retrieved: 2026-10-09T20:20:46Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.origin

Source artifact SHA-256: 1d9c27beb3780a153bc6d80817bf098539e5c605107da0e88f34d6e0d56f3e4f

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-09-8cc1db47c7f9 · Record review: source checked

1 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: model-execution-20261009-eval-oconnell2023-dgx-gpu2-deepvariant

areas
dna-genomes
contexts
clinical_research
origin
independent_paper
protocol
model-execution-20261009-protocol-oconnell2023-deepvariant
version
Primary source as retrieved 2026-10-09
comparison
protocol id: model-execution-20261009-protocol-oconnell2023-deepvariant; dataset version: Not reported; split: Single sample; population: HG002 30x; inputs: FASTQ; adaptation: Not reported; metric implementation: Workflow wall-clock; cost from on-demand hourly price; aggregation: Single run; budget: One recorded run per machine; no fixed hardware budget, machine type is part of each configuration (Table 1 VM-type)
source locator
Table 1, row 9 (DGX, GPU2, DeepVariant)
missing metadata
comparison.dataset version: reason: unreported
Related records

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