Published comparison transcribed from the pinned source; not reproduced.
1 evaluation · 2 results. Different protocols are not a single leaderboard.
Protocol: COSMIC frequent vs gnomAD common missense, AUPRC (GPN-MSA Supplementary Table 4) · Dataset: COSMIC frequent vs gnomAD common missense variants (GPN-MSA paper)
Sorted by AUPRC (maximum over three random seeds; zero-shot) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | AUPRC (maximum over three random seeds; zero-shot) | AUPRC (mean over three random seeds; zero-shot) |
|---|---|---|
| GPN-MSA ablation 'Window size = 32' (Supplementary Table 4)Evaluation | 0.328 | 0.323 |
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: GPN-MSA ablation 'Window size = 32' (Supplementary Table 4) | Protocol: COSMIC frequent vs gnomAD common missense, AUPRC (GPN-MSA Supplementary Table 4) Dataset: COSMIC frequent vs gnomAD common missense variants (GPN-MSA paper) | 0.328 AUPRC (maximum over three random seeds; zero-shot) unitless · higher Uncertainty: Not reported by the source: Only mean and max over seeds are printed Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceWindow size = 32 on COSMIC (GPN-MSA Supplementary Table 4) gfm-guides-20261014-gpnmsa-protocol-ablation-cosmic-auprc Aggregation: Not reported GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) · Supplementary Table 4 (PDF page 23), row 'Window size = 32', column 'COSMIC' / 'max' |
| Configuration: GPN-MSA ablation 'Window size = 32' (Supplementary Table 4) | Protocol: COSMIC frequent vs gnomAD common missense, AUPRC (GPN-MSA Supplementary Table 4) Dataset: COSMIC frequent vs gnomAD common missense variants (GPN-MSA paper) | 0.323 AUPRC (mean over three random seeds; zero-shot) unitless · higher Uncertainty: Not reported by the source: Only mean and max over seeds are printed Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceWindow size = 32 on COSMIC (GPN-MSA Supplementary Table 4) gfm-guides-20261014-gpnmsa-protocol-ablation-cosmic-auprc Aggregation: Not reported GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) · Supplementary Table 4 (PDF page 23), row 'Window size = 32', column 'COSMIC' / 'mean' |
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COSMIC frequent vs gnomAD common missense, AUPRC (GPN-MSA Supplementary Table 4)
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18 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Comparison: adaptation zero-shot Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: aggregation Mean and maximum over three random seeds where applicable (printed as separate columns) Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: budget Not reported Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: dataset version Not reported Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: inputs Reference genome and multispecies alignment around each variant (GPN-MSA rows); alignment column or conservation scores (method rows) Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: metric implementation Not reported Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: population Not reported Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | missing or unspecified No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: protocol id gfm-guides-20261014-gpnmsa-protocol-ablation-cosmic-auprc Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Comparison: split Whole labelled set Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Origin author_reported Context-only references | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Supplementary Table 4 row 'Window size = 32', column group 'COSMIC' Version: bioRxiv v2, posted 2024-04-06 | not individually reviewed No individual claim review recorded author reported Audit detailsField: Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
Stable ID: gfm-guides-20261014-gpnmsa-eval-ablation-window-32-cosmic