rewirebio.iobenchmarks
Dataset subset

Six BEELINE datasets, TFs+500 (Ye et al. 2026)

All six BEELINE scRNA-seq datasets (hESC, hHep, mDC, mHSC-E, mHSC-GM, mHSC-L) with the TFs+500 gene set; results are means across datasets.

Evaluation results

84 evaluations · 168 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: DeepSEM (Ye et al. 2026 baseline)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.05 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.038

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DeepSEM GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'ML', column 'DeepSEM'
Configuration: DeepSEM (Ye et al. 2026 baseline)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.05 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.044

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DeepSEM GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'ML', column 'DeepSEM'
Configuration: Geneformer attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.07 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.076

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'attn', column 'Geneformer'
Configuration: Geneformer attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.16 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.259

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'attn', column 'Geneformer'
Configuration: Geneformer coshid GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.964 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.071

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer coshid GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'coshid', column 'Geneformer'
Configuration: Geneformer coshid GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.01 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.069

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer coshid GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'coshid', column 'Geneformer'
Configuration: Geneformer costok GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.983 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.031

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer costok GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'costok', column 'Geneformer'
Configuration: Geneformer costok GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.945 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.089

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Geneformer costok GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'costok', column 'Geneformer'
Configuration: GENIE3 (Ye et al. 2026 baseline)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.032

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GENIE3 GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'ML', column 'GENIE3'
Configuration: GENIE3 (Ye et al. 2026 baseline)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.05 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.056

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GENIE3 GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'ML', column 'GENIE3'
Configuration: GRNBoost (Ye et al. 2026 baseline)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.02 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.044

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GRNboost GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'ML', column 'GRNboost'
Configuration: GRNBoost (Ye et al. 2026 baseline)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.994 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.078

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GRNboost GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'ML', column 'GRNboost'
Configuration: LangCell attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.05 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.087

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LangCell attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'attn', column 'Langcell'
Configuration: LangCell attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.99 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.184

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LangCell attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'attn', column 'Langcell'
Configuration: LangCell coshid GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.01 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.055

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LangCell coshid GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'coshid', column 'Langcell'
Configuration: LangCell coshid GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.01 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.052

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LangCell coshid GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'coshid', column 'Langcell'
Configuration: LangCell costok GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.983 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.031

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LangCell costok GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'costok', column 'Langcell'
Configuration: LangCell costok GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.944 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.090

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

LangCell costok GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'costok', column 'Langcell'
Configuration: scCello attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.999 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.020

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scCello attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'attn', column 'scCello'
Configuration: scCello attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.02 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.082

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scCello attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'attn', column 'scCello'
Configuration: scCello coshid GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.01 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.040

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scCello coshid GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'coshid', column 'scello'
Configuration: scCello coshid GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.986 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.073

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scCello coshid GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'coshid', column 'scCello'
Configuration: scCello costok GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.991 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.023

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scCello costok GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'costok', column 'scello'
Configuration: scCello costok GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
0.981 Early precision ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.045

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scCello costok GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 4, block 'Cell-type-specific', row 'mean', column group 'costok', column 'scCello'
Configuration: scFoundation attn GRN (Ye et al. 2026)Protocol: Ye et al. 2026 GRN reconstruction, TFs+500, cell-type-specific ChIP-seq reference
Dataset subset: Six BEELINE datasets, TFs+500 (Ye et al. 2026)
1.01 AUPRC ratio (TFs+500 gene set; cell-type-specific ChIP-seq reference; mean across six datasets)
unitless · higher

Uncertainty: SD 0.010

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

scFoundation attn GRN on six BEELINE datasets (mean), TFs+500, cell-type-specific ChIP-seq

lit-cells-networks-20261011-ye2026grn-protocol-tf-plus-500-cell-type-specific-chip-seq

Aggregation: Not reported

Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models · Table 6, block 'Cell-type-specific', row 'mean', column group 'attn', column 'scFoundation'

Source checking is not independent reproduction. Release 2026-10-23-5347695500ed.

Research readiness

0 of 4 readiness checks met. These checks assess whether the evidence supports a reproducible investigation; a source-checked score alone does not meet them.

Readiness checks, gaps and artifacts

Release 2026-10-23-5347695500ed · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

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  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Metrics are recomputed from the saved predictions: not yet verified
  • Sample annotations are recorded: not yet verified
  • Dependence between samples is assessed: not yet verified

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

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  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • A pinned run recipe exists: not yet verified
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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • File checksums match the recorded files: not yet verified
  • Predictions are matched to the right samples: not yet verified
  • Score meaning and direction are confirmed: not yet verified
  • Independent validation data exist: not yet verified
  • Overlap with training data is checked: not yet verified

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Subset and evaluation context

This record describes a particular subset or cohort used in an evaluation. Its results do not describe the full dataset.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

4 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-23-5347695500ed
Property and statementOriginal source and locationReview and provenance
Source location
Section 2.1; Appendix A.1
Context-only references
Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models

Original source ↗

Section 2.1; Appendix A.1

Version: bioRxiv preprint version 1, posted 2026-05-20
Retrieved: 2026-10-11T21:36:31Z

not individually reviewed

No individual claim review recorded

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Field: attributes.source_locator

Source artifact SHA-256: a6c3aae569b1f1614c71569efb0692f15700aea473c64c7bc0bc660e81330dc7

Hash scope: Exact bytes of one download. bioRxiv serves slightly different PDF bytes per download (41 bytes differed between two downloads 2 minutes apart; pdftotext output identical), so the gzip copy in artifacts/ is the reference.

Inspected artifact

Split
No train/test split; zero-shot network inference on each full expression matrix
Context-only references
Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models

Original source ↗

Section 2.1; Appendix A.1

Version: bioRxiv preprint version 1, posted 2026-05-20
Retrieved: 2026-10-11T21:36:31Z

not individually reviewed

No individual claim review recorded

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Field: attributes.split

Source artifact SHA-256: a6c3aae569b1f1614c71569efb0692f15700aea473c64c7bc0bc660e81330dc7

Hash scope: Exact bytes of one download. bioRxiv serves slightly different PDF bytes per download (41 bytes differed between two downloads 2 minutes apart; pdftotext output identical), so the gzip copy in artifacts/ is the reference.

Inspected artifact

Description
All six BEELINE scRNA-seq datasets (hESC, hHep, mDC, mHSC-E, mHSC-GM, mHSC-L) with the TFs+500 gene set; results are means across datasets.
Context-only references
Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models

Original source ↗

Section 2.1; Appendix A.1

Version: bioRxiv preprint version 1, posted 2026-05-20
Retrieved: 2026-10-11T21:36:31Z

not individually reviewed

No individual claim review recorded

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Field: description

Source artifact SHA-256: a6c3aae569b1f1614c71569efb0692f15700aea473c64c7bc0bc660e81330dc7

Hash scope: Exact bytes of one download. bioRxiv serves slightly different PDF bytes per download (41 bytes differed between two downloads 2 minutes apart; pdftotext output identical), so the gzip copy in artifacts/ is the reference.

Inspected artifact

Name
Six BEELINE datasets, TFs+500 (Ye et al. 2026)
Context-only references
Benchmarking Static Gene Regulatory Network Reconstruction and Dynamic Transition Probing in Single-Cell Foundation Models

Original source ↗

Section 2.1; Appendix A.1

Version: bioRxiv preprint version 1, posted 2026-05-20
Retrieved: 2026-10-11T21:36:31Z

not individually reviewed

No individual claim review recorded

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Field: name

Source artifact SHA-256: a6c3aae569b1f1614c71569efb0692f15700aea473c64c7bc0bc660e81330dc7

Hash scope: Exact bytes of one download. bioRxiv serves slightly different PDF bytes per download (41 bytes differed between two downloads 2 minutes apart; pdftotext output identical), so the gzip copy in artifacts/ is the reference.

Inspected artifact

Sources and history

Release 2026-10-23-5347695500ed · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: lit-cells-networks-20261011-ye2026grn-data-tf-plus-500-six-datasets

areas
biological-networks; single-cell
contexts
research
split
No train/test split; zero-shot network inference on each full expression matrix
source locator
Section 2.1; Appendix A.1
missing metadata
version: reason: unreported
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