| Configuration: BPNet (large), trained from scratch (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.865 (± 0.026) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.026 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBPNet (large) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'BPNet (large)', column 'Splice site all'; printed identically in Supplementary Table 7 |
|---|
| Configuration: BPNet (original), trained from scratch (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.793 (± 0.072) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.072 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBPNet (original) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'BPNet (original)', column 'Splice site all'; printed identically in Supplementary Table 7 |
|---|
| Configuration: BPNet (X-large), trained from scratch (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.745 (± 0.016) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.016 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceBPNet (X-large) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'BPNet (X-large)', column 'Splice site all'; printed identically in Supplementary Table 7 |
|---|
| Configuration: DNABERT-2, parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.855 (± 0.005) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.005 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceDNABERT-2 on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'DNABERT-2', column 'Splice site all' |
|---|
| Configuration: Enformer, parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.739 (± 0.011) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.011 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceEnformer on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'Enformer', column 'Splice site all' |
|---|
| Configuration: HyenaDNA-1KB, parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.854 (± 0.053) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.053 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceHyenaDNA-1KB on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'HyenaDNA-1KB', column 'Splice site all' |
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| Configuration: HyenaDNA-32KB, parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.907 (± 0.018) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.018 Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceHyenaDNA-32KB on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'HyenaDNA-32KB', column 'Splice site all' |
|---|
| Configuration: NT-1000G (2.5B), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.956 (± 0.004) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.004 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-1000G (2.5B) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-1000G (2.5B)', column 'Splice site all' |
|---|
| Configuration: NT-1000G (2.5B), probing (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.438 (± 0.008) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.008 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-1000G (2.5B) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'NT-1000G (2.5B)', column 'Splice site all' |
|---|
| Configuration: NT-1000G (500M), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.939 (± 0.004) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.004 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-1000G (500M) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-1000G (500M)', column 'Splice site all' |
|---|
| Configuration: NT-1000G (500M), probing (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.355 (± 0.01) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.01 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-1000G (500M) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'NT-1000G (500M)', column 'Splice site all' |
|---|
| Configuration: NT 2.5B Randomly Initialized, trained from scratch (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.421 (± 0.024) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.024 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT 2.5B Randomly Initialized on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT 2.5B Randomly Initialized', column 'Splice site all' |
|---|
| Configuration: NT 500M Randomly Initialized, trained from scratch (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.363 (± 0.038) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.038 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT 500M Randomly Initialized on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT 500M Randomly Initialized', column 'Splice site all' |
|---|
| Configuration: NT-HumanRef (500M), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.939 (± 0.003) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.003 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-HumanRef (500M) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-HumanRef (500M)', column 'Splice site all' |
|---|
| Configuration: NT-HumanRef (500M), probing (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.414 (± 0.005) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.005 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-HumanRef (500M) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'NT-HumanRef (500M)', column 'Splice site all' |
|---|
| Configuration: NT-Multispecies (2.5B), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.964 (± 0.003) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.003 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-Multispecies (2.5B) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-Multispecies (2.5B)', column 'Splice site all' |
|---|
| Configuration: NT-Multispecies (2.5B), probing (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.491 (± 0.01) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.01 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-Multispecies (2.5B) on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'NT-Multispecies (2.5B)', column 'Splice site all' |
|---|
| Configuration: NT-Multispecies-v2 (100M), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.96 (± 0.005) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.005 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-Multispecies-v2 (100M) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-Multispecies-v2 (100M)', column 'Splice site all' |
|---|
| Configuration: NT-Multispecies-v2 (250M), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.965 (± 0.003) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.003 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-Multispecies-v2 (250M) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-Multispecies-v2 (250M)', column 'Splice site all' |
|---|
| Configuration: NT-Multispecies-v2 (500M), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.967 (± 0.004) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.004 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-Multispecies-v2 (500M) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-Multispecies-v2 (500M)', column 'Splice site all' |
|---|
| Configuration: NT-Multispecies-v2 (50M), parameter-efficient fine-tuning (NT benchmark) | Protocol: NT benchmark Splice site all, fine-tuning (PEFT) Dataset: NT benchmark Splice site all | 0.928 (± 0.005) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.005 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceNT-Multispecies-v2 (50M) on NT benchmark Splice site all (fine-tuning) lit-genomics-20261011-ntbench-protocol-splice-site-all-fine-tuning Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 7, row 'NT-Multispecies-v2 (50M)', column 'Splice site all' |
|---|
| Configuration: Raw Probe, probing of raw sequence (NT benchmark) | Protocol: NT benchmark Splice site all, probing Dataset: NT benchmark Splice site all | 0.234 (± 0.003) MCC (median over 10 cross-validation folds) unitless · higher Uncertainty: SD 0.003 Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceRaw Probe on NT benchmark Splice site all (probing) lit-genomics-20261011-ntbench-protocol-splice-site-all-probing Aggregation: Not reported Nucleotide Transformer: Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 6, row 'Raw Probe', column 'Splice site all'; printed identically in Supplementary Table 7 |
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