rewirebio.iobenchmarks
Dataset

Feng pathogenic/common SNP short-window dataset

Feng pathogenic/common SNP short-window scored population; Feng et al. 2025.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-07-1448159e6a81 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

7 evaluations · 14 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Caduceus-Ph (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.696 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Caduceus-Ph pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, Caduceus-Ph row, AUC column (deterministic XML extraction)
Configuration: Caduceus-Ph (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.735 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Caduceus-Ph pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, Caduceus-Ph row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.
Configuration: DNABERT-2 (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.538 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT-2 pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, DNABERT-2 row, AUC column (deterministic XML extraction)
Configuration: DNABERT-2 (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.134 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

DNABERT-2 pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, DNABERT-2 row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.
Configuration: GROVER (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.603 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GROVER pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, GROVER row, AUC column (deterministic XML extraction)
Configuration: GROVER (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.369 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

GROVER pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, GROVER row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.
Configuration: HyenaDNA (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.612 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

HyenaDNA pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, HyenaDNA row, AUC column (deterministic XML extraction)
Configuration: HyenaDNA (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.395 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

HyenaDNA pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, HyenaDNA row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.
Configuration: NT-v2 (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.732 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NT-v2 pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, NT-v2 row, AUC column (deterministic XML extraction)
Configuration: NT-v2 (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.881 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

NT-v2 pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, NT-v2 row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.
Configuration: Sei, hidden states* (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.66 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Sei, hidden states* pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, Sei, hidden states* row, AUC column (deterministic XML extraction)
Configuration: Sei, hidden states* (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.557 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Sei, hidden states* pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, Sei, hidden states* row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.
Configuration: Sei, output tracks* (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.664 pathogenic/common SNP AUC
AUC · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Sei, output tracks* pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, Sei, output tracks* row, AUC column (deterministic XML extraction)
Configuration: Sei, output tracks* (pathogenic/common SNP classification)Protocol: Feng pathogenic-versus-common SNP classification
Dataset: Feng pathogenic/common SNP short-window dataset
0.605 pathogenic/common SNP Cohen's d
Cohen's d · unknown

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

Sei, output tracks* pathogenic/common SNP evaluation

Table 5, frozen embeddings + random forest classifier

Aggregation: Not reported

Benchmarking DNA foundation models for genomic and genetic tasks · Table 5, Sei, output tracks* row, Cohen's d column (deterministic XML extraction). Signed effect size; the source does not state a universal desirable sign/direction, so direction is recorded as unknown rather than assumed higher-is-better.

Source checking is not independent reproduction. Release 2026-10-07-1448159e6a81.

Dataset and evaluation context

A dataset supplies biological observations. The evaluation protocol defines how those observations are split, used and scored.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

5 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-07-1448159e6a81
Property and statementOriginal source and locationReview and provenance
attributes.population
Short generated/chromosome-boundary-filtered window: 6,000 bp. 22,239 pathogenic/17,398 common SNPs.
Context-only references
Benchmarking DNA foundation models for genomic and genetic tasks

Original source ↗

No field-specific location recorded

Version: PMC12663285.1
Retrieved: 2026-09-17T07:54:51.004119+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.population

Source artifact SHA-256: 5d8ca9bcf88cc1b38ad667906a2e4699b1aefa6d31c6f49259784930353f3202

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.split
Three disjoint outer chromosome test groups (3/6/9/12/16/18/19/21; 2/5/11/14/17/20/22/X; 1/4/7/8/10/13/15), each held out in turn with fourfold inner-chromosome cross-validation for hyperparameter tuning.
Context-only references
Benchmarking DNA foundation models for genomic and genetic tasks

Original source ↗

No field-specific location recorded

Version: PMC12663285.1
Retrieved: 2026-09-17T07:54:51.004119+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.split

Source artifact SHA-256: 5d8ca9bcf88cc1b38ad667906a2e4699b1aefa6d31c6f49259784930353f3202

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

attributes.version
Not reported
Context-only references
Benchmarking DNA foundation models for genomic and genetic tasks

Original source ↗

No field-specific location recorded

Version: PMC12663285.1
Retrieved: 2026-09-17T07:54:51.004119+00:00

missing or unspecified

No individual claim review recorded

Audit details

Field: attributes.version

Source artifact SHA-256: 5d8ca9bcf88cc1b38ad667906a2e4699b1aefa6d31c6f49259784930353f3202

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

description
Feng pathogenic/common SNP short-window scored population; Feng et al. 2025.
Context-only references
Benchmarking DNA foundation models for genomic and genetic tasks

Original source ↗

No field-specific location recorded

Version: PMC12663285.1
Retrieved: 2026-09-17T07:54:51.004119+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 5d8ca9bcf88cc1b38ad667906a2e4699b1aefa6d31c6f49259784930353f3202

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

name
Feng pathogenic/common SNP short-window dataset
Context-only references
Benchmarking DNA foundation models for genomic and genetic tasks

Original source ↗

No field-specific location recorded

Version: PMC12663285.1
Retrieved: 2026-09-17T07:54:51.004119+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 5d8ca9bcf88cc1b38ad667906a2e4699b1aefa6d31c6f49259784930353f3202

Hash scope: Exact retrieved primary paper artifact bytes.

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-10-07-1448159e6a81 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: amp-feng-20261007-dataset-variant-short

areas
dna-genomes
missing metadata
split: Exact per-fold scored counts and post-window-filter denominators are unreported; not asserted as zero.
population
Short generated/chromosome-boundary-filtered window: 6,000 bp. 22,239 pathogenic/17,398 common SNPs.
split
Three disjoint outer chromosome test groups (3/6/9/12/16/18/19/21; 2/5/11/14/17/20/22/X; 1/4/7/8/10/13/15), each held out in turn with fourfold inner-chromosome cross-validation for hyperparameter tuning.
version
Not reported
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