Historical Erlangen MTB protein-function interpretation
Prior P/LP, VUS and B/LB functional-impact review; different classification semantics from oncogenicity.
Overview
Prior P/LP, VUS and B/LB functional-impact review; different classification semantics from oncogenicity.
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Evaluations and results
1 evaluation · 2 results. Different protocols are not a single leaderboard.
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| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: Historical Erlangen MTB protein-function interpretation | Protocol: OncoVI three-class assessment: MTB selected expert reassessment Dataset: MTB selected expert reassessment | 34% expert_concordance percent · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceHistorical MTB agreement with expert oncogenicity reassessment Not reported Aggregation: Not reported Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, validation data set, paragraph ending 46/135; Figure 4A |
| Configuration: Historical Erlangen MTB protein-function interpretation | Protocol: OncoVI three-class assessment: MTB selected expert reassessment Dataset: MTB selected expert reassessment | 46 expert_concordant_variants count · unknown Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceHistorical MTB agreement with expert oncogenicity reassessment Not reported Aggregation: Not reported Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Results, validation data set, paragraph ending 46/135; Figure 4A |
Source checking is not independent reproduction. Release 2026-09-30-e37e3ab1284d.
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Evidence
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Sources and history
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Release 2026-09-30-e37e3ab1284d · Record review: source checked
1 source records and release history
- Oncogenicity Variant Interpreter (OncoVI) Supports Harmonized Somatic Variant Interpretation in Precision Oncology · Original source · 2026 final full text in Europe PMC XML
Technical metadata and extraction receipts
Stable ID: uc-clinical-20260930-oncovi-prior-mtb
- areas
- dna-genomes
- contexts
- clinical_research
- review
- method: automated_source_review; reviewer: Codex clinical coverage worker; date: 2026-09-30; note: Transcription from inspected primary source. No execution, independent replication or human scientific review.; source id: uc-clinical-20260930-source-oncovi
Related records
- configuration: Historical MTB interpretation comparator
- configuration: Historical MTB agreement with expert oncogenicity reassessment