| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 0.01 f1-score fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'F1' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 292 false-negative-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'False negative' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 248,759 false-positive-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'False positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 0 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'Positive predictive value' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 0.76 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive rate' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 920 true-positive-count count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, targeted RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 0.05 f1-score fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'F1' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, targeted RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 7 false-negative-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'False negative' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, targeted RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 3,916 false-positive-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'False positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, targeted RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 0.03 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'Positive predictive value' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, targeted RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 0.94 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive rate' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: All fusions, targeted RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 106 true-positive-count count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on all fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-all-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 0.89 f1-score fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'F1' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 8 false-negative-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'False negative' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 5 false-positive-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'False positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 0.91 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'Positive predictive value' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 0.87 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive rate' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines) | 53 true-positive-count count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, conventional RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-conventional Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, targeted RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 0.89 f1-score fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'F1' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, targeted RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 3 false-negative-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'False negative' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, targeted RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 2 false-positive-count count · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'False positive' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, targeted RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 0.91 precision fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'Positive predictive value' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, targeted RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 0.88 recall fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive rate' (PDF page text) |
|---|
| Configuration: JAFFA-direct v2.2 (Tamura et al. 2026) | Protocol: Driver fusions, targeted RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset: Haematologic cancer cell lines, hybridisation-capture targeted RNA-seq (26 cell lines) | 21 true-positive-count count · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceJAFFA-direct on driver fusions, targeted RNA-seq (Tamura et al. 2026) rna-fusion-20261009-protocol-tamura2026-driver-targeted Aggregation: Not reported Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Targeted RNA-seq of cell lines', row 'JAFFA-direct', column 'True positive' (PDF page text) |
|---|