Configuration

Training class prior / majority (MFASS v2 canonical held-out split)

Constant training-class prior scored on all 8,324 canonical MFASS v2 held-out variants. Tied top-100 predictions are one fixed label-independent ordering, not ranking ability.

1 evaluation · 3 results

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Evaluations and results

1 evaluation · 3 results. Different protocols are not a single leaderboard.

Protocol: MFASS v2 · Dataset: MFASS v2 eligible assay cohort

Sorted by AUROC (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	AUROC	Average precision	Precision at 100
Training class prior / majority (MFASS v2 canonical held-out split)Evaluation	0.5	0.0378	0.04

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Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: Training class prior / majority (MFASS v2 canonical held-out split)	Protocol: MFASS v2 Dataset: MFASS v2 eligible assay cohort	0.5 AUROC unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 8324/8324 scored	Rewire evaluation · Source checked Methods, coverage and source Training class prior / majority on MFASS v2 canonical held-out split MFASS v2 canonical held-out split Aggregation: Not reported Training class prior / majority: report; Training class prior / majority: audit · metrics.auroc
Configuration: Training class prior / majority (MFASS v2 canonical held-out split)	Protocol: MFASS v2 Dataset: MFASS v2 eligible assay cohort	0.0378 Average precision unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 8324/8324 scored	Rewire evaluation · Source checked Methods, coverage and source Training class prior / majority on MFASS v2 canonical held-out split MFASS v2 canonical held-out split Aggregation: Not reported Training class prior / majority: report; Training class prior / majority: audit · metrics.average_precision_sklearn
Configuration: Training class prior / majority (MFASS v2 canonical held-out split)	Protocol: MFASS v2 Dataset: MFASS v2 eligible assay cohort	0.04 Precision at 100 unitless · higher Uncertainty: Not reported by the source: Not estimated; one selected evaluation. Coverage: 8324/8324 scored	Rewire evaluation · Source checked Methods, coverage and source Training class prior / majority on MFASS v2 canonical held-out split MFASS v2 canonical held-out split Aggregation: Not reported Training class prior / majority: report; Training class prior / majority: audit · metrics.precision_at_capacity

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

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Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
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Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

2 source records and release history

Training class prior / majority: report · Original source · 1663d1f04b2bbd6dfcff77fea78129d30b0de191
Training class prior / majority: audit · Original source · 1663d1f04b2bbd6dfcff77fea78129d30b0de191

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Technical metadata and extraction receipts

Stable ID: rewire-local-20260921-configuration-mfass-prior

areas: dna-genomes
source locator: model; model_configuration; protocol_configuration.embedding_probe; execution
configuration: baseline id: training-prior-v1; baseline version: 1; binary: positive-class prevalence; multiclass: majority; lowest-class tie
model: name: Training class prior / majority; training overlap: protocol-permitted training only; no pretraining
environment: architecture: arm64; container digest: unreported; container runtime: unreported; platform: macOS-26.6.2-arm64-arm-64bit; python: 3.11.13; rewirebench: 0.4.0; sdk code sha256: 08cbbaac2aa8f60af5c43af7a83410e9690b44c5e4d162fbe1e5766885952fce; sif sha256: unreported
training overlap: protocol-permitted training only; no pretraining
method role: null control

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