GPN-MSA (evaluation mode not printed (Table 4 has no Eval. column), GUANinE v1.1)
GPN-MSA: Regime M (MSA-based method).
Overview
An explanatory profile has not yet been reviewed for this record.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
1 evaluation · 1 result. Different protocols are not a single leaderboard.
Filter evaluations
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: GPN-MSA (evaluation mode not printed (Table 4 has no Eval. column), GUANinE v1.1) | Protocol: GUANinE v1.1 clinvar-snv, Spearman rho x100 (Table 4) Dataset: GUANinE clinvar-snv test set | 80.7 Spearman (GUANinE v1.1 test set) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPN-MSA on GUANinE clinvar-snv lit-genomics-20261011-guanine-protocol-clinvar-snv Aggregation: Not reported GUANinE v1.1 reveals complementarity of supervised and genomic language models · Table 4, row 'GPN-MSA', column 'clinvar-snv' (ρ) |
Source checking is not independent reproduction. Release 2026-10-22-1b7cf027e4f6.
Use this configuration
How it works, versions and access
Related profile: GPN-MSA. This page retains the exact record and its evaluation context.
Strengths, limitations and unresolved questions
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
2 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Relationship: configuration of gfm-guides-20261014-gpnmsa-model-gpn-msa Individual claims | GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) Configuration name as printed in its source (GPN-MSA); GPN-MSA identity from gfm-guides-20261014-gpnmsa-source-biorxiv-v2 (Abstract) and gfm-guides-20261014-gpnmsa-source-gpn-msa-doc Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: bioRxiv v2, posted 2024-04-06 | source checked ["scope-review"] · 2026-10-14 Audit detailsAccepted in the independent review of 2026-10-14. See docs/reviews/2026-10-14-gfm-guide-evidence-review.md. Field: Claim: identity-20261014-f74c141ad479a4dc3a26 Source artifact SHA-256: Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer. |
| Relationship: configuration of gfm-guides-20261014-gpnmsa-model-gpn-msa Individual claims | GUANinE v1.1 reveals complementarity of supervised and genomic language models Configuration name as printed in its source (GPN-MSA); GPN-MSA identity from gfm-guides-20261014-gpnmsa-source-biorxiv-v2 (Abstract) and gfm-guides-20261014-gpnmsa-source-gpn-msa-doc Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML | source checked ["scope-review"] · 2026-10-14 Audit detailsAccepted in the independent review of 2026-10-14. See docs/reviews/2026-10-14-gfm-guide-evidence-review.md. Field: Claim: identity-20261014-f74c141ad479a4dc3a26 Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- GUANinE v1.1 reveals complementarity of supervised and genomic language models · Original source · Bioinformatics 2026, btag427 (issue date 2026-08-01); PMC13501288 full-text XML
Technical metadata and extraction receipts
Stable ID: lit-genomics-20261011-guanine-config-gpn-msa-mode-unprinted
- areas
- dna-genomes
- contexts
- research
- method types
- conventional_pipeline
- reported name
- GPN-MSA
- foundation model eligible
- true
- parameters
- Regime M (MSA-based method); evaluation evaluation mode not printed (Table 4 has no Eval. column); context column ''
- source locator
- Table 4 row 'GPN-MSA', columns Reg., Eval. and Context
- access reuse
- Not stated in the source; see the model's own release
- missing metadata
- version: reason: unreported; note: Only the printed row label identifies the checkpoint
- model identity note
- GPN-MSA, the multiple-sequence-alignment member of the GPN family
- provenance note
- GPN-MSA as evaluated in GUANinE v1.1.