rewirebio.iobenchmarks
Configuration

DecoderOnly (+ perturbations)

DecoderOnly (+ perturbations): Selected per dataset and task by Optuna HPO (at least 60 trials), then retrained with 5 seeds.

1 evaluation · 4 results

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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

1 evaluation · 4 results. Different protocols are not a single leaderboard.

Protocol: PerturBench v4 mode-collapse diagnostics on Srivatsan20 · Dataset subset: Srivatsan20 (PerturBench v4 covariate-transfer split)

Sorted by Perturbench matrix distance (lower is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configurationPerturbench matrix distancePerturbench RMSE of meanPerturbench RMSE rankPerturbench RMSE transposed rank
DecoderOnly (+ perturbations)Evaluation40.60.0210.1160.232
All 4 result rows with coverage, uncertainty and sources
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Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: DecoderOnly (+ perturbations)Protocol: PerturBench v4 mode-collapse diagnostics on Srivatsan20
Dataset subset: Srivatsan20 (PerturBench v4 covariate-transfer split)
40.6 Perturbench matrix distance
unit-unreported · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DecoderOnly (+ perturbations) on PerturBench v4 srivatsan20-collapse

lit-cells-networks-20261011-perturbench-v4-protocol-srivatsan20-mode-collapse

Aggregation: Not reported

PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis (arXiv v4) · Table 12, row 'DecoderOnly (+ perturbations)', column 'Matrix distance'
Configuration: DecoderOnly (+ perturbations)Protocol: PerturBench v4 mode-collapse diagnostics on Srivatsan20
Dataset subset: Srivatsan20 (PerturBench v4 covariate-transfer split)
0.116 Perturbench RMSE rank
fraction · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DecoderOnly (+ perturbations) on PerturBench v4 srivatsan20-collapse

lit-cells-networks-20261011-perturbench-v4-protocol-srivatsan20-mode-collapse

Aggregation: Not reported

PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis (arXiv v4) · Table 12, row 'DecoderOnly (+ perturbations)', column 'RMSE mean rank'
Configuration: DecoderOnly (+ perturbations)Protocol: PerturBench v4 mode-collapse diagnostics on Srivatsan20
Dataset subset: Srivatsan20 (PerturBench v4 covariate-transfer split)
0.021 Perturbench RMSE of mean
unit-unreported · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DecoderOnly (+ perturbations) on PerturBench v4 srivatsan20-collapse

lit-cells-networks-20261011-perturbench-v4-protocol-srivatsan20-mode-collapse

Aggregation: Not reported

PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis (arXiv v4) · Table 12, row 'DecoderOnly (+ perturbations)', column 'RMSE mean'
Configuration: DecoderOnly (+ perturbations)Protocol: PerturBench v4 mode-collapse diagnostics on Srivatsan20
Dataset subset: Srivatsan20 (PerturBench v4 covariate-transfer split)
0.232 Perturbench RMSE transposed rank
fraction · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

DecoderOnly (+ perturbations) on PerturBench v4 srivatsan20-collapse

lit-cells-networks-20261011-perturbench-v4-protocol-srivatsan20-mode-collapse

Aggregation: Not reported

PerturBench: Benchmarking Machine Learning Models for Cellular Perturbation Analysis (arXiv v4) · Table 12, row 'DecoderOnly (+ perturbations)', column 'RMSE mean transposed-rank'

Source checking is not independent reproduction. Release 2026-10-23-5347695500ed.

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Claims, original sources and review scope · Release 2026-10-23-5347695500ed
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Release 2026-10-23-5347695500ed · Record review: source checked

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Technical metadata and extraction receipts

Stable ID: lit-cells-networks-20261011-perturbench-v4-config-decoderonly-plus-perturbations

areas
single-cell
contexts
research
method types
supervised_machine_learning
reported name
DecoderOnly (+ perturbations)
source locator
Appendix C.7, Table 12
foundation model eligible
false
hyperparameters
Selected per dataset and task by Optuna HPO (at least 60 trials), then retrained with 5 seeds (Section 4.3)
access reuse
Code in the PerturBench repository (github.com/altoslabs/perturbench)
missing metadata
version: reason: unreported; note: No code commit is printed for the v4 runs
provenance note
PerturBench Decoder-only baseline with cell line and perturbations as input (Appendix C.7.1; Figure C.2B), as named in the mode-collapse Table 12. The source does not say whether this is the 'Decoder' row of Tables 2 and 5.
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