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HyenaDNA (zero-shot embedding)

HyenaDNA (zero-shot embedding): DNA language model.

2 evaluations · 2 results

Overview

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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.

Evaluations and results

2 evaluations · 2 results. Different protocols are not a single leaderboard.

Sorted by AUROC (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

All 2 result rows with coverage, uncertainty and sources
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Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: HyenaDNA (zero-shot embedding)Task: DART-Eval VS-AFRICAN-AUROC: Variant scoring on Chromatin QTLs in African LCLs, AUROC
Dataset subset: Chromatin QTLs in African LCLs (DART-Eval split)
0.515 AUROC
unitless · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

HyenaDNA (zero-shot embedding) on DART-Eval VS-AFRICAN-AUROC: Variant scoring on Chromatin QTLs in African LCLs, AUROC

Score the effect of a variant on chromatin accessibility, against the measured QTL call.

Aggregation: Not reported

DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 6, row(African HyenaDNA), column(zero-shot embedding auroc)
Configuration: HyenaDNA (zero-shot embedding)Task: DART-Eval VS-YORUBAN-AUROC: Variant scoring on DNase QTLs in Yoruban LCLs, AUROC
Dataset subset: DNase QTLs in Yoruban LCLs (DART-Eval split)
0.515 AUROC
unitless · higher

Uncertainty: Not yet extracted

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

HyenaDNA (zero-shot embedding) on DART-Eval VS-YORUBAN-AUROC: Variant scoring on DNase QTLs in Yoruban LCLs, AUROC

Score the effect of a variant on chromatin accessibility, against the measured QTL call.

Aggregation: Not reported

DART-Eval: A Comprehensive DNA Language Model Evaluation Benchmark on Regulatory DNA · Table 6, row(Yoruban HyenaDNA), column(zero-shot embedding auroc)

Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.

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Evidence

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Evidence table

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Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
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Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: dart-eval-method-hyenadna-zero-shot-embedding

areas
dna-genomes
source locator
Table 1, row(HyenaDNA)
missing metadata
checkpoint revision: reason: unreported; parameters: reason: unextracted
provenance note
DNA language model evaluated by the DART-Eval authors in the zero-shot embedding setting.
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