Strengths and considerations
No source-reviewed explanatory claims are recorded here yet.
Configuration
AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins
AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins. This is the configuration evaluated in the Nature paper, not an identification of the current hosted API revision.
Sources (3)
AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps PerformanceOverview
Key specifications have not been extracted for this record. See the linked evaluation and sources for the reported setup.
limited source coverage · Automated source review, 2026-09-17. All specifications and missing details
Evaluations and results
2 evaluations · 2 results. Different protocols are not a single leaderboard.
Filter evaluations
Applied filters: All linked evaluations
| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins | Protocol: chromatin contact-map prediction (AlphaGenome paper) Dataset subset: chromatin contact-map prediction: evaluated data subset | 0.79 Per-cell type
@4kb pearsonr correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceCompare predicted and observed contact maps for each held-out interval and cell type. Aggregation: Mean Pearson correlation across held-out interval evaluations; cell types remain explicit before reporting the summary. AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K40 |
| Configuration: AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins | Protocol: Cell-type difference in chromatin contact-map prediction (AlphaGenome paper) Dataset subset: Cell-type difference in chromatin contact-map prediction: evaluated data subset | 0.42 Cell-type difference
@4kb pearsonr correlation · higher Uncertainty: Not reported Coverage: Not reported scored / Not reported eligible | Author-reported evaluation · Source checkedMethods, coverage and sourceReimplement the Orca H1-hESC minus HFF difference evaluation on the same held-out windows. Aggregation: Mean Pearson correlation across held-out interval evaluations; the difference-map endpoint is distinct from individual-cell-type accuracy. AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K41 |
Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.
Use this model
How it works, versions and access
Related profile: AlphaGenome. This page retains the exact record and its evaluation context.
How it works
Evaluated configuration
Fold-specific AlphaGenome contact-map evaluation on the intersection of Orca test chromosomes 9 and 10 with AlphaGenome/Borzoi fold-0 held-out intervals. Compare predicted and observed contact maps for each held-out interval and cell type.
Sources (3)
AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps PerformanceStrengths, limitations and unresolved questions
Strengths and limitations
Limitations and conditions
- The publication result does not establish equivalence to another checkpoint or hosted service.
Sources (3)
AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance
Profile review details
Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.
Stable record: alphagenome-2026-model-3ee8e21d05b3b446Specifications
Inputs, training, access and other details
Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.
| Property | Description and evidence |
|---|---|
| Evaluated system | AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb binsSources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance |
| Checkpoint artifact | Not established for these paper scores; no released checkpoint is inferred. · Needs further source reviewSources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance |
| Evaluation scope | Paper-evaluated AlphaGenome configurationSources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance |
| Model type | Not extracted or verified for this record. |
| Inputs | Not extracted or verified for this record. |
| Outputs | Not extracted or verified for this record. |
| Parameters | Not extracted or verified for this record. |
| Training data | Not extracted or verified for this record. |
| Context limits | Not extracted or verified for this record. |
| Access | Not extracted or verified for this record. |
| Code licence | Not extracted or verified for this record. |
| Weights licence | Not extracted or verified for this record. |
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
21 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Evaluated system AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Evaluated system AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins Individual claims | AlphaGenome Nature 2026 supplementary methods 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplement to Nature version of record, 28 January 2026; content hash pinned | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact publisher PDF bytes Format: original_pdf |
| Evaluated system AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature version of record, 28 January 2026 | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx |
| Checkpoint artifact Not established for these paper scores; no released checkpoint is inferred. Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | unextracted automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Checkpoint artifact Not established for these paper scores; no released checkpoint is inferred. Individual claims | AlphaGenome Nature 2026 supplementary methods 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplement to Nature version of record, 28 January 2026; content hash pinned | unextracted automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact publisher PDF bytes Format: original_pdf |
| Checkpoint artifact Not established for these paper scores; no released checkpoint is inferred. Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature version of record, 28 January 2026 | unextracted automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx |
| Evaluation scope Paper-evaluated AlphaGenome configuration Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
| Evaluation scope Paper-evaluated AlphaGenome configuration Individual claims | AlphaGenome Nature 2026 supplementary methods 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Supplement to Nature version of record, 28 January 2026; content hash pinned | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact publisher PDF bytes Format: original_pdf |
| Evaluation scope Paper-evaluated AlphaGenome configuration Individual claims | AlphaGenome Nature 2026 supplementary comparison tables 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Nature version of record, 28 January 2026 | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx |
| Limitation The publication result does not establish equivalence to another checkpoint or hosted service. Individual claims | alphagenome: Journal full-text XML 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: Retrieved page snapshot; no immutable publisher revision supplied | source checked automated source review · 2026-09-17 Audit detailsPrimary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction. Field: Source artifact SHA-256: Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact |
Sources and history
View linked audit checks and correction history
Release 2026-09-29-06401fd5b220 · Record review: needs review
3 source records and release history
- AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
- AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
- alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied
Technical metadata and extraction receipts
Stable ID: alphagenome-2026-model-3ee8e21d05b3b446
- areas
- dna-genomes
- entity level
- method
- configuration type
- paper_evaluation
- version
- AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins
- legacy kinds
- model
- entity classification
- review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: source-alphagenome-nature2026-tables; source-alphagenome-nature2026-supplementary-methods; evidence-official-56e5abfb5f12f1cd3b20; source locator: 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance; ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
Related records
- family: AlphaGenome
- model: AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins: Cell-type difference in chromatin contact-map prediction
- model: AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins: chromatin contact-map prediction
- subject: AlphaGenome fold-0 contact-map model, bilinearly resized to Orca 4 kb bins: family