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Configuration

Orca (paper Table 3)

Orca (paper Table 3). A comparator reported by the AlphaGenome authors; protocol pages specify the dataset and adaptation.

Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

2 evaluations · 2 results

Overview

Key specifications have not been extracted for this record. See the linked evaluation and sources for the reported setup.

limited source coverage · Automated source review, 2026-09-17. All specifications and missing details

Evaluations and results

2 evaluations · 2 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Orca (paper Table 3)Protocol: chromatin contact-map prediction (AlphaGenome paper)
Dataset subset: chromatin contact-map prediction: evaluated data subset
0.741 Per-cell type @4kb pearsonr
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Orca (paper Table 3): chromatin contact-map prediction

Compare predicted and observed contact maps for each held-out interval and cell type.

Aggregation: Mean Pearson correlation across held-out interval evaluations; cell types remain explicit before reporting the summary.

AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J40
Configuration: Orca (paper Table 3)Protocol: Cell-type difference in chromatin contact-map prediction (AlphaGenome paper)
Dataset subset: Cell-type difference in chromatin contact-map prediction: evaluated data subset
0.294 Cell-type difference @4kb pearsonr
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

Orca (paper Table 3): Cell-type difference in chromatin contact-map prediction

Reimplement the Orca H1-hESC minus HFF difference evaluation on the same held-out windows.

Aggregation: Mean Pearson correlation across held-out interval evaluations; the difference-map endpoint is distinct from individual-cell-type accuracy.

AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J41

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Use this model

How it works, versions and access

How it works

How this comparator was evaluated

The source table identifies Orca. Compare predicted and observed contact maps for each held-out interval and cell type.

Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance
Strengths, limitations and unresolved questions

Strengths and limitations

Strengths and considerations

No source-reviewed explanatory claims are recorded here yet.

Profile review details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Stable record: alphagenome-2026-comparator-84dbea922a1f788f

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-17. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
PropertyDescription and evidence
Reported methodOrca
Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance
Exact checkpointNot established by the summary table; inspect the protocol and original implementation. · Needs further source review
Sources (3)AlphaGenome Nature 2026 supplementary comparison tables; AlphaGenome Nature 2026 supplementary methods; alphagenome: Journal full-text XML · 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance
Model typeNot extracted or verified for this record.
InputsNot extracted or verified for this record.
OutputsNot extracted or verified for this record.
ParametersNot extracted or verified for this record.
Training dataNot extracted or verified for this record.
Context limitsNot extracted or verified for this record.
AccessNot extracted or verified for this record.
Code licenceNot extracted or verified for this record.
Weights licenceNot extracted or verified for this record.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

15 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
Reported method
Orca
Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Reported method
Orca
Individual claims
AlphaGenome Nature 2026 supplementary methods

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

Reported method
Orca
Individual claims
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.0.value

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

Exact checkpoint
Not established by the summary table; inspect the protocol and original implementation.
Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

unextracted

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Exact checkpoint
Not established by the summary table; inspect the protocol and original implementation.
Individual claims
AlphaGenome Nature 2026 supplementary methods

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

unextracted

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

Exact checkpoint
Not established by the summary table; inspect the protocol and original implementation.
Individual claims
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

unextracted

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.facts.1.value

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

Limitation
A table label does not establish identity with any other catalogue configuration bearing the same name.
Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.limitations.0.text

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Limitation
A table label does not establish identity with any other catalogue configuration bearing the same name.
Individual claims
AlphaGenome Nature 2026 supplementary methods

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.limitations.0.text

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

Limitation
A table label does not establish identity with any other catalogue configuration bearing the same name.
Individual claims
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.limitations.0.text

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

How this comparator was evaluated
The source table identifies Orca. Compare predicted and observed contact maps for each held-out interval and cell type.
Individual claims
alphagenome: Journal full-text XML

Original source ↗

'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

source checked

automated source review · 2026-09-17

Audit details

Primary-source transcription and separate automated source review. No human sign-off or independent experimental reproduction.

Field: attributes.profile.sections.0.body

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-29-06401fd5b220 · Record review: needs review

3 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: alphagenome-2026-comparator-84dbea922a1f788f

areas
dna-genomes
entity level
method
configuration type
reported_configuration
version
Orca (paper Table 3)
legacy kinds
model
entity classification
review date: 2026-09-17; rationale: This source-scoped entry preserves the method/configuration actually named in an evaluation. It is neither a global family identity nor proof of an immutable checkpoint; the linked evaluation retains adaptation, fitting and scoring details.; source ids: source-alphagenome-nature2026-tables; source-alphagenome-nature2026-supplementary-methods; evidence-official-56e5abfb5f12f1cd3b20; source locator: 'Suppl Table 3 Track performance'!A40:N40; Supplementary Methods pp.23–24, Contact Maps Performance; ambiguities: Configuration means the source-labelled evaluated identity. It does not establish missing checkpoint hashes, default settings or equivalence to same-named records in other papers.
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