Zoonomia Cactus 241-way phyloP (AlphaGenome Atlas v1)
Zoonomia 241-way Cactus alignment phyloP score at the variant position; maximum over the deleted interval for deletions.
2 evaluations · 2 results4 open disagreements between studies involve its model
Overview
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Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Evaluations and results
2 evaluations · 2 results. Different protocols are not a single leaderboard.
Dataset: Saturation genome editing screens of 13 genes from 14 studies (AlphaGenome Atlas)
Sorted by AUPRC (pooled held-out SGE screens, functionally abnormal vs normal, SNVs and indels) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Protocol and dataset | AUPRC (pooled held-out SGE screens, functionally abnormal vs normal, SNVs and indels) | AUPRC (pooled held-out SGE screens, functionally abnormal vs normal, SNVs only) |
|---|---|---|---|
| Zoonomia Cactus 241-way phyloP (AlphaGenome Atlas v1)Evaluation | SGE held-out screens pooled, SNVs and indels, AUPRC (AlphaGenome Atlas) | 0.408 | Not reported |
| Zoonomia Cactus 241-way phyloP (AlphaGenome Atlas v1)Evaluation | SGE held-out screens pooled, functionally abnormal versus normal SNVs, AUPRC (AlphaGenome Atlas) | Not reported | 0.296 |
All 2 result rows with coverage, uncertainty and sources
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Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.
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How it works, versions and access
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Evidence
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Evidence table
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Sources and history
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
1 source record and release history
- AlphaGenome Atlas: in silico mutagenesis of the entire human genome (Cheng, Taylor, Nicolaisen et al., medRxiv 2026) · Original source · medRxiv preprint version 1, posted 2026-09-20; full-text PDF with supplementary figures and tables (83 pages)
Technical metadata and extraction receipts
Stable ID: ag-atlas-20261019-config-cactus-241way
- areas
- dna-genomes
- contexts
- research
- method types
- conventional_pipeline
- reported name
- Cactus 241-way
- source locator
- Methods 'Obtaining baseline scores' (pages 26 to 27)