rewirebio.iobenchmarks
Evidence claim

SpliceAI2 training data

Training data of SpliceAI2

Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).

Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

12 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Claimed field
training_data
Context-only references
A unified framework for quantitative splicing and transcript prediction (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv preprint version 1, posted 2026-10-11; full-text PDF (57 pages)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: f8f3db2c3943d4827b670bc2e962e0cec8fbe96e0b1acf9d4a9b9f0c7a78c06b

Hash scope: SHA-256 of one retrieval of the bioRxiv PDF. bioRxiv stamps the PDF when serving it (XMP ModifyDate, MetadataDate, DocumentID, InstanceID, Info ModDate and the second trailer ID), so later retrievals differ. A reviewer retrieval on 2026-10-13 of the same length (2,679,664 bytes) had SHA-256 407f5884427dda0226e0ce1f022e4479d3ff2b243da18bcc691eb345b0e04a6a and ModDate D:20261013063115-07'00'; its bytes differ only in those fields and its pdftotext text layer is identical to the pinned copy.

Inspected artifact

Claimed field
training_data
Context-only references
Supplementary Table 1: training RNA-seq samples and junctions per species (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv version 1 supplement DC1 (757673_file02.tsv)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: f46bf8c10880cc2359b6070c1e85af8e5ae7768f75e2580970f6078b54415be7

Hash scope: Hash scope not separately documented; inspect source record

Source location
Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'
Context-only references
A unified framework for quantitative splicing and transcript prediction (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv preprint version 1, posted 2026-10-11; full-text PDF (57 pages)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: f8f3db2c3943d4827b670bc2e962e0cec8fbe96e0b1acf9d4a9b9f0c7a78c06b

Hash scope: SHA-256 of one retrieval of the bioRxiv PDF. bioRxiv stamps the PDF when serving it (XMP ModifyDate, MetadataDate, DocumentID, InstanceID, Info ModDate and the second trailer ID), so later retrievals differ. A reviewer retrieval on 2026-10-13 of the same length (2,679,664 bytes) had SHA-256 407f5884427dda0226e0ce1f022e4479d3ff2b243da18bcc691eb345b0e04a6a and ModDate D:20261013063115-07'00'; its bytes differ only in those fields and its pdftotext text layer is identical to the pinned copy.

Inspected artifact

Source location
Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'
Context-only references
Supplementary Table 1: training RNA-seq samples and junctions per species (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv version 1 supplement DC1 (757673_file02.tsv)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: f46bf8c10880cc2359b6070c1e85af8e5ae7768f75e2580970f6078b54415be7

Hash scope: Hash scope not separately documented; inspect source record

Claimed value
Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).
Context-only references
A unified framework for quantitative splicing and transcript prediction (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv preprint version 1, posted 2026-10-11; full-text PDF (57 pages)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: f8f3db2c3943d4827b670bc2e962e0cec8fbe96e0b1acf9d4a9b9f0c7a78c06b

Hash scope: SHA-256 of one retrieval of the bioRxiv PDF. bioRxiv stamps the PDF when serving it (XMP ModifyDate, MetadataDate, DocumentID, InstanceID, Info ModDate and the second trailer ID), so later retrievals differ. A reviewer retrieval on 2026-10-13 of the same length (2,679,664 bytes) had SHA-256 407f5884427dda0226e0ce1f022e4479d3ff2b243da18bcc691eb345b0e04a6a and ModDate D:20261013063115-07'00'; its bytes differ only in those fields and its pdftotext text layer is identical to the pinned copy.

Inspected artifact

Claimed value
Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).
Context-only references
Supplementary Table 1: training RNA-seq samples and junctions per species (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv version 1 supplement DC1 (757673_file02.tsv)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: f46bf8c10880cc2359b6070c1e85af8e5ae7768f75e2580970f6078b54415be7

Hash scope: Hash scope not separately documented; inspect source record

Description
Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).
Context-only references
A unified framework for quantitative splicing and transcript prediction (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv preprint version 1, posted 2026-10-11; full-text PDF (57 pages)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: f8f3db2c3943d4827b670bc2e962e0cec8fbe96e0b1acf9d4a9b9f0c7a78c06b

Hash scope: SHA-256 of one retrieval of the bioRxiv PDF. bioRxiv stamps the PDF when serving it (XMP ModifyDate, MetadataDate, DocumentID, InstanceID, Info ModDate and the second trailer ID), so later retrievals differ. A reviewer retrieval on 2026-10-13 of the same length (2,679,664 bytes) had SHA-256 407f5884427dda0226e0ce1f022e4479d3ff2b243da18bcc691eb345b0e04a6a and ModDate D:20261013063115-07'00'; its bytes differ only in those fields and its pdftotext text layer is identical to the pinned copy.

Inspected artifact

Description
Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).
Context-only references
Supplementary Table 1: training RNA-seq samples and junctions per species (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv version 1 supplement DC1 (757673_file02.tsv)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: f46bf8c10880cc2359b6070c1e85af8e5ae7768f75e2580970f6078b54415be7

Hash scope: Hash scope not separately documented; inspect source record

Relationship: subject
rna-splicing-20261013-spliceai2-model-spliceai2
Context-only references
A unified framework for quantitative splicing and transcript prediction (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv preprint version 1, posted 2026-10-11; full-text PDF (57 pages)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: links:subject:rna-splicing-20261013-spliceai2-model-spliceai2

Source artifact SHA-256: f8f3db2c3943d4827b670bc2e962e0cec8fbe96e0b1acf9d4a9b9f0c7a78c06b

Hash scope: SHA-256 of one retrieval of the bioRxiv PDF. bioRxiv stamps the PDF when serving it (XMP ModifyDate, MetadataDate, DocumentID, InstanceID, Info ModDate and the second trailer ID), so later retrievals differ. A reviewer retrieval on 2026-10-13 of the same length (2,679,664 bytes) had SHA-256 407f5884427dda0226e0ce1f022e4479d3ff2b243da18bcc691eb345b0e04a6a and ModDate D:20261013063115-07'00'; its bytes differ only in those fields and its pdftotext text layer is identical to the pinned copy.

Inspected artifact

Relationship: subject
rna-splicing-20261013-spliceai2-model-spliceai2
Context-only references
Supplementary Table 1: training RNA-seq samples and junctions per species (Jaganathan et al., bioRxiv 2026)

Original source ↗

Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: bioRxiv version 1 supplement DC1 (757673_file02.tsv)
Retrieved: 2026-10-13T12:40:34Z

not individually reviewed

No individual claim review recorded

Audit details

Field: links:subject:rna-splicing-20261013-spliceai2-model-spliceai2

Source artifact SHA-256: f46bf8c10880cc2359b6070c1e85af8e5ae7768f75e2580970f6078b54415be7

Hash scope: Hash scope not separately documented; inspect source record

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: rna-splicing-20261013-spliceai2-claim-training-data

field
training_data
value
Trained on splice site and junction usage from 314,745 short-read RNA-seq samples (67,493,026 junctions) in human and nine other mammalian species, and on transcript usage from 330 ENCODE long-read samples in human and mouse. Human: 127,431 samples from recount3 (GTEx, TCGA, CCLE and other SRA-derived projects).
source locator
Main 'Hierarchical model of RNA splicing' paragraph 1; Methods 'Training datasets'; Supplementary Table 1 rows 'Homo_sapiens' and 'Total'
review
method: source-hash-verification; pdf-text-parse; independent-cell-check; reviewer: claude; reviewer note: Claude (Opus 5.5) research agent, independent reviewer; did not extract this batch; no human review claimed; date: 2026-10-13; artifact sha256: f8f3db2c3943d4827b670bc2e962e0cec8fbe96e0b1acf9d4a9b9f0c7a78c06b; retrieval url: https://www.biorxiv.org/content/10.64898/2026.10.08.757673v1.full.pdf; method note: Supplementary Table 1 re-downloaded (SHA-256 matches) and its Homo_sapiens and Total rows re-read; main-text sentence located in the reviewer's pdftotext output.; note: Checked against the pinned source by the independent reviewer; verdict and correction list in docs/reviews/use-cases/spliceai2-2026-10-13.md and this batch's review.json. Developer-reported value, not reproduced. Extraction method: Text asserted in the pinned PDF; Supplementary Table 1 totals and the human row asserted in the pinned TSV (extract/build_batch.py).
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