rewirebio.iobenchmarks
Evidence claim

SPIN + ESM2-35M: description

Description of SPIN + ESM2-35M

Classifies proteins into family-specific functional classes with an ESM2-35M backbone whose first six encoder layers are frozen, adapting a question-answering architecture to locate a domain span and classify the selected region.

Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

14 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Claimed field
description
Context-only references
facebookresearch/esm README.md

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac
Retrieved: 2026-09-16T20:00:00.816433+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed field
description
Context-only references
Scaling the profile of life by function with SPIN

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558225+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 9701843e93bf7fa3ead71e19693fb07d483f1022379871adfb04486783722a9d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Previous value
Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers.
Context-only references
facebookresearch/esm README.md

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac
Retrieved: 2026-09-16T20:00:00.816433+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: 8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Previous value
Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers.
Context-only references
Scaling the profile of life by function with SPIN

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558225+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: 9701843e93bf7fa3ead71e19693fb07d483f1022379871adfb04486783722a9d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)
Context-only references
facebookresearch/esm README.md

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac
Retrieved: 2026-09-16T20:00:00.816433+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)
Context-only references
Scaling the profile of life by function with SPIN

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558225+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 9701843e93bf7fa3ead71e19693fb07d483f1022379871adfb04486783722a9d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed value
Classifies proteins into family-specific functional classes with an ESM2-35M backbone whose first six encoder layers are frozen, adapting a question-answering architecture to locate a domain span and classify the selected region.
Context-only references
facebookresearch/esm README.md

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac
Retrieved: 2026-09-16T20:00:00.816433+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: 8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed value
Classifies proteins into family-specific functional classes with an ESM2-35M backbone whose first six encoder layers are frozen, adapting a question-answering architecture to locate a domain span and classify the selected region.
Context-only references
Scaling the profile of life by function with SPIN

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558225+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: 9701843e93bf7fa3ead71e19693fb07d483f1022379871adfb04486783722a9d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.
Context-only references
facebookresearch/esm README.md

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac
Retrieved: 2026-09-16T20:00:00.816433+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.
Context-only references
Scaling the profile of life by function with SPIN

Original source ↗

Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558225+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 9701843e93bf7fa3ead71e19693fb07d483f1022379871adfb04486783722a9d

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

How to read the evidence

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: metadata-correction-6e776887757906c63771

areas
proteins-complexes
field
description
previous value
Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers.
value
Classifies proteins into family-specific functional classes with an ESM2-35M backbone whose first six encoder layers are frozen, adapting a question-answering architecture to locate a domain span and classify the selected region.
source locator
Reviewed profile (2026-09-16): summary at 3 Results/3.4 Analysis of the SH3 protein family and representational augmentation across clades (paragraph 4); 3 Results/3.3 SPIN on thioredoxin, a widespread protein family (paragraph 1); architecture fact at 2 Materials and methods/2.1 SPIN architecture (paragraph 1); 2 Materials and methods/2.1 SPIN architecture (paragraph 7); description text also read at Abstract; 2 Materials and methods/2.1 SPIN architecture (layer freezing)
review
method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked all 11 scTab and MPRabc method descriptions against PMC11298532 and PMC13232518, and Lazypipe-nt, scaLR, CATHe2, DiffDock-NMDN, PC-mer and Hi-Enhancer against their papers; all match. The other pipeline descriptions are consistent with their pinned papers.; receipt: data/omics/qa-descriptions-20261011-c/review.json
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