Evidence claim

LIST-S2: description

Description of LIST-S2

Quantifies the conservation of a position from local sequence identity and taxonomic distances in a multiple alignment, for sequences from any organism rather than human alone.

Replace a category-only description with a sourced functional description (issue #88). Historical releases retain the original value.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

7 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Claimed field description Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact
Previous value Variant effect predictor for missense variants. Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact
Source location qa-descriptions-20261011-e-source-list-s2: Abstract Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact
Claimed value Quantifies the conservation of a position from local sequence identity and taxonomic distances in a multiple alignment, for sequences from any organism rather than human alone. Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.value` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact
Description Replace a category-only description with a sourced functional description (issue #88). Historical releases retain the original value. Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact
Relationship: subject somatic-oncogenicity-20261009-method-list-s2 Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `links:subject:somatic-oncogenicity-20261009-method-list-s2` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact
Name LIST-S2: description Context-only references	LIST-S2: taxonomy based sorting of deleterious missense mutations across species Original source ↗ qa-descriptions-20261011-e-source-list-s2: Abstract Version: Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020 Retrieved: 2026-10-11T01:38:38Z	not individually reviewed No individual claim review recorded Audit details Field: `name` Source artifact SHA-256: `5867606de985e78a008b910e4a49c91e6f9ef4e3f37dc5bad92f98d7bf935d76` Hash scope: SHA-256 of one retrieval of the Europe PMC full-text XML. These renderings are not always byte-stable; the article text is the evidence. Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release history

LIST-S2: taxonomy based sorting of deleterious missense mutations across species · Original source · Europe PMC full-text XML for PMC7319545, Nucleic Acids Research 2020

Download this release (gzip)

Technical metadata and extraction receipts

Stable ID: metadata-correction-436844384474b6856e48

areas: dna-genomes
contexts: clinical_research
method types: specialist
field: description
previous value: Variant effect predictor for missense variants.
value: Quantifies the conservation of a position from local sequence identity and taxonomic distances in a multiple alignment, for sequences from any organism rather than human alone.
source locator: qa-descriptions-20261011-e-source-list-s2: Abstract
review: method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved with two corrections, both applied: the MutFormer source licence is CC BY 4.0 per the arXiv abstract page, and the MetaRNN source locator now names the Background passage. Checked the 27 Chen 2020 descriptions row by row against Table 1 (PMC7033911) and spot-checked AlphaMissense, MisFit, popEVE, VARITY, MetaRNN, MutFormer and gMVP against their abstracts; accurate. Licences on the other new sources match Europe PMC.; receipt: data/omics/qa-descriptions-20261011-e/review.json

Related records

subject: LIST-S2

Suggest a correction