rewirebio.iobenchmarks
Evidence claim

AlphaGenome distilled model time per variant

Inference hardware of AlphaGenome

The distilled student model makes predictions for all modalities and cell types with a single device call per variant, taking less than 1 s on an NVIDIA H100 GPU.

Descriptive fact transcribed from the pinned source.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

7 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Claimed field
inference_hardware
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Limitations
1 values
  • Upper bound stated in prose; batch size, sequence length and whether model loading is included are not stated.
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.limitations

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed value
The distilled student model makes predictions for all modalities and cell types with a single device call per variant, taking less than 1 s on an NVIDIA H100 GPU.
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Descriptive fact transcribed from the pinned source.
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Relationship: subject
catalog-model-alphagenome
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: links:subject:catalog-model-alphagenome

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
AlphaGenome distilled model time per variant
Context-only references
Advancing regulatory variant effect prediction with AlphaGenome (Nature), Europe PMC full-text XML

Original source ↗

Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'

Version: Nature, version of record 28 January 2026; PMC12851941 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: gfm-guide-20261014-claim-alphagenome-variant-scoring-time

field
inference_hardware
value
The distilled student model makes predictions for all modalities and cell types with a single device call per variant, taking less than 1 s on an NVIDIA H100 GPU.
source locator
Results, 'Unifying DNA sequence-to-function model', paragraph 2: 'Taking less than 1 s on an NVIDIA H100 GPU, the student model is highly efficient for large-scale variant effect prediction relative to the alternative approach of ensembling several independently trained models.'
review
method: source-hash-verification; ai-assisted-source-review; method note: Each source sentence the claim rests on asserted verbatim in the reviewer's own text extraction (review/check_gfm_guide.py); the claim text was then read against them.; reviewer: claude; reviewer note: Independent Claude (Opus 5.5) review agent for PR #150; did not extract this batch; no human review claimed; date: 2026-10-14; artifact sha256: 50d10530afd474d85702813bc9c9e5431406515e44f3425d64603fdb647fee13; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12851941/fullTextXML; note: Claim matches the source.
limitations
Upper bound stated in prose; batch size, sequence length and whether model loading is included are not stated.
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