BioML-bench task SPIKE_SARS2_Starr_2020
Predict ACE2 binding fitness for SARS-CoV-2 spike RBD single-site variants.
No reviewed evaluations are linked here in this release. See the sources below.
Overview
An explanatory profile has not yet been reviewed for this record.
Consult the linked sources for architecture or protocol details. Missing evidence is not evidence of a missing capability.
Published results still to collect
This release has no source-checked evaluations linked to this page. It does not mean that the benchmark has no published results.
Charts will appear when compatible result tables have been checked against their sources.
Methods and evaluation design
Procedure, tasks and evaluated configurations
Additional methodological details, tasks and evaluated configurations have not yet been extracted into a structured profile for this task. Consult the linked sources and evaluation records below.
Run instructions
No runnable recipe has been reviewed for this task. Dataset access, model requirements, licences and compute requirements must be checked against its sources before execution.
A task describes a biological question. Choose a linked protocol to obtain concrete split and scoring instructions.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
0 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|
No evidence rows match these filters. Choose another scope or clear the search.
Sources and history
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
2 source records and release history
- BioML-bench: Evaluation of AI Agents for End-to-End Biomedical ML · Original source · bioRxiv 2025.09.01.673319 version 3, posted 2025-09-28 (versions 1 and 2 posted 2025-09-04 and 2025-09-07)
- science-machine/biomlbench repository at commit 673f3d8 · Original source · Git commit 673f3d8d3462fc6cdcbbd9695fba612b9332ca65 (2025-09-14, head of main at retrieval); README title 'BioML-bench (v0.1-alpha)'
Technical metadata and extraction receipts
Stable ID: lit-agents-20261013-biomlbench-task-spike-sars2-starr-2020
- areas
- protein-function
- contexts
- research
- task
- Predict ACE2 binding fitness for SARS-CoV-2 spike RBD single-site variants.
- task type
- Protein Engineering
- dataset
- ProteinGym DMS assay SPIKE_SARS2_Starr_2020_binding; Spearman averaged over the random, modulo and contiguous 5-fold cross-validation schemes
- version
- BioML-bench v0.1-alpha; repository task ID proteingym-dms/SPIKE_SARS2_Starr_2020_binding
- source locator
- Table 3, row 'SPIKE_SARS2_Starr_2020'; repository experiments/biomlbench_v0.1a.txt and task config.yaml
Related records
- part of: BioML-bench
- parent: BioML-bench protein engineering domain: agent leaderboard percentile over 6 tasks
- part of: ProteinGym