BioML-bench task CBX4_HUMAN_multi-sub
Predict stability of human CBX4 SUMO ligase multi-substitution variants.
No reviewed evaluations are linked here in this release. See the sources below.
Overview
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Methods and evaluation design
Procedure, tasks and evaluated configurations
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Evidence
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Evidence table
Inspect claims, sources and review details
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2 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Dataset ProteinGym DMS assay CBX4_HUMAN_Tsuboyama_2023_2K28 (repository task list); its description.md says it contains multi-substitution variants of CBX4_HUMAN, matching Table 3 Individual claims | science-machine/biomlbench repository at commit 673f3d8 Repository experiments/biomlbench_v0.1a.txt and biomlbench/tasks/proteingym-dms/CBX4_HUMAN_Tsuboyama_2023_2K28/description.md at commit 673f3d8 Version: Git commit 673f3d8d3462fc6cdcbbd9695fba612b9332ca65 (2025-09-14, head of main at retrieval); README title 'BioML-bench (v0.1-alpha)' | source checked ["source-hash-verification","independent-cell-check"] · 2026-10-13 Audit detailsCBX4_HUMAN_Tsuboyama_2023_2K28 is the multi-substitution CBX4 assay that Table 3 labels CBX4_HUMAN_multi-sub. See docs/reviews/2026-10-13-biomlbench-agents.md. Field: Claim: metadata-correction-biomlbench-20261013-task-cbx4-human-multi-sub-dataset Source artifact SHA-256: Hash scope: SHA-256 of the codeload tar.gz archive for the commit; two downloads gave identical bytes. Per-file hashes of the files cited are in sources.md. Extraction artifact SHA-256: |
| Scope note Table 3 labels this task CBX4_HUMAN_multi-sub; the repository task list names CBX4_HUMAN_Tsuboyama_2023_2K28, whose description says it contains multi-substitution variants of CBX4_HUMAN. Treated as the same assay under a shortened label; recorded under the paper's label. Individual claims | science-machine/biomlbench repository at commit 673f3d8 Repository biomlbench/tasks/proteingym-dms/CBX4_HUMAN_Tsuboyama_2023_2K28/description.md at commit 673f3d8 Version: Git commit 673f3d8d3462fc6cdcbbd9695fba612b9332ca65 (2025-09-14, head of main at retrieval); README title 'BioML-bench (v0.1-alpha)' | source checked ["source-hash-verification","independent-cell-check"] · 2026-10-13 Audit detailsThe CBX4 label difference is not an assay conflict. See docs/reviews/2026-10-13-biomlbench-agents.md. Field: Claim: metadata-correction-biomlbench-20261013-task-cbx4-human-multi-sub-scope-note Source artifact SHA-256: Hash scope: SHA-256 of the codeload tar.gz archive for the commit; two downloads gave identical bytes. Per-file hashes of the files cited are in sources.md. Extraction artifact SHA-256: |
Sources and history
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
1 source record and release history
- BioML-bench: Evaluation of AI Agents for End-to-End Biomedical ML · Original source · bioRxiv 2025.09.01.673319 version 3, posted 2025-09-28 (versions 1 and 2 posted 2025-09-04 and 2025-09-07)
Technical metadata and extraction receipts
Stable ID: lit-agents-20261013-biomlbench-task-cbx4-human-multi-sub
- areas
- protein-function
- contexts
- research
- task
- Predict stability of human CBX4 SUMO ligase multi-substitution variants.
- task type
- Protein Engineering
- dataset
- ProteinGym DMS assay CBX4_HUMAN_Tsuboyama_2023_2K28 (repository task list); its description.md says it contains multi-substitution variants of CBX4_HUMAN, matching Table 3
- version
- BioML-bench v0.1-alpha
- source locator
- Table 3, row 'CBX4_HUMAN_multi-sub'
- scope note
- Table 3 labels this task CBX4_HUMAN_multi-sub; the repository task list names CBX4_HUMAN_Tsuboyama_2023_2K28, whose description says it contains multi-substitution variants of CBX4_HUMAN. Treated as the same assay under a shortened label; recorded under the paper's label.