Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores
Primary source retrieved and hashed for the structural hypotheses use-case pass.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
23 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| attributes.access_and_reuse CC BY 4.0 permits redistribution of the article bytes. Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.archive_note Gzip copy (gzip -n -9) archived in the batch as artifacts/smorodina2026-article.xml.gz. Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.artifact_sha256 0ad24054d98fd1888fa8bf3120f76e22f7bf6b1965261b16f045986d72c50732 Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.artifact_url https://www.ebi.ac.uk/europepmc/webservices/rest/PPR1221387/fullTextXML Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.doi 10.64898/2026.03.02.709004 Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.extraction_method JATS XML parse (xml.etree), by extract/extract_structural.py Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.licence CC-BY-4.0 Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.media_type application/xml Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.publication_status preprint Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
| attributes.retrieval_note bioRxiv returned HTTP 429 (Cloudflare 1015) for the source XML, and the Europe PMC supplementary files returned a browser challenge, so only the Europe PMC full text was read. Supplementary Tables 1, 3 and 4 were not read. Source metadata | Structural Plausibility Without Binding Specificity: Limits of AI-Based Antibody-Antigen Structure Prediction Confidence Scores No field-specific location recorded Version: bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed | catalogued No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: JATS XML parse (xml.etree), by extract/extract_structural.py |
Sources and history
Release 2026-10-10-6e93f504adfc · Record review: source checked
Technical metadata and extraction receipts
Stable ID: structural-20261009-source-smorodina2026
- areas
- proteins-complexes
- contexts
- research
- url
- https://doi.org/10.64898/2026.03.02.709004
- artifact url
- https://www.ebi.ac.uk/europepmc/webservices/rest/PPR1221387/fullTextXML
- version
- bioRxiv version 1, posted 2026-03-03; Europe PMC preprint full text PPR1221387 (manuscript EMS215481); not peer reviewed
- retrieved at
- 2026-10-09T21:25:48Z
- artifact sha256
- 0ad24054d98fd1888fa8bf3120f76e22f7bf6b1965261b16f045986d72c50732
- publication status
- preprint
- licence
- CC-BY-4.0
- media type
- application/xml
- doi
- 10.64898/2026.03.02.709004
- source locator
- Full artifact bytes; per-record locators on each record
- access and reuse
- CC BY 4.0 permits redistribution of the article bytes.
- archive note
- Gzip copy (gzip -n -9) archived in the batch as artifacts/smorodina2026-article.xml.gz.
- extraction method
- JATS XML parse (xml.etree), by extract/extract_structural.py
- scope note
- Authors: Smorodina, Ali, Kropivšek Brumat, Salicari, Miklavc, Kappassov, Fu, Sormanni, de Marco and Greiff. None developed AlphaFold3, Boltz-2 or Chai-1. Competing interests printed: V.G. declares advisory, consulting and employment roles with antibody-discovery and biotechnology companies, none of them a developer of the three tools compared.
- retrieval note
- bioRxiv returned HTTP 429 (Cloudflare 1015) for the source XML, and the Europe PMC supplementary files returned a browser challenge, so only the Europe PMC full text was read. Supplementary Tables 1, 3 and 4 were not read.