rewirebio.iobenchmarks
Result

Hit rate (designs confirmed as binders by BLI, out of designs selected for testing, as stated in Section 4.2; Section 2.4 prints 2.5% (5/201) for the same round) of Adaptyv EGFR competition round 1 selected submissions on Adaptyv EGFR competition round 1 tested designs

3% Hit rate (designs confirmed as binders by BLI, out of designs selected for testing, as stated in Section 4.2; Section 2.4 prints 2.5% (5/201) for the same round)

Methods

Tested configuration
Adaptyv EGFR competition round 1 selected submissions
Protocol
Adaptyv EGFR competition BLI binding screen
Dataset
Adaptyv EGFR competition round 1 tested designs
Procedure
Adaptyv EGFR competition BLI binding screen
Evaluation
Adaptyv EGFR competition round 1 binding rate
Coverage
Not reported scored / Not reported eligible
Uncertainty
Not reported by the source: No interval is printed.
Evidence
Independent external evaluation · source checkedCrowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025) · Section 4.1: 'from 3% in the first round to 13% (Figure 8)'

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split
Not reported
Adaptation
Not reported
Scoring implementation
Share of selected designs confirmed as binders by BLI

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Reported result
3%
Individual claims
Crowdsourced Protein Design: Lessons From the Adaptyv EGFR Binder Competition (Cotet et al., bioRxiv 2025)

Original source ↗

Section 4.1: 'from 3% in the first round to 13% (Figure 8)'

Version: bioRxiv preprint version 1
Retrieved: 2026-10-22T12:01:00Z

source checked

["source-hash-verification","independent-cell-check","ai-assisted-source-review"] · 2026-10-22T15:00:00Z

independent paper

Source has a recorded evidence concern. Consult its source page before using the claim.

Audit details

Reviewed in docs/reviews/use-cases/binder-2026-10-22.md. Automated AI review of the source transcription only; it is not human scientific review and nothing here was reproduced experimentally.

Field: attributes.printed_value

Source artifact SHA-256: 17039d69ecc37f45f6c402511b8f4497ce631003689fa95ad1ab221f8f787a4f

Hash scope: SHA-256 of one retrieval of a mutable web page. The hash describes that retrieval, not a stable artifact.

Inspected artifact

Extraction artifact SHA-256: 17039d69ecc37f45f6c402511b8f4497ce631003689fa95ad1ab221f8f787a4f

Extraction artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: uc-binder-20261022-result-adaptyv-r1-hitrate-section-4-2

denominator
201
denominator note
201 designs selected for testing. The sentence points at Figure 8, which reports binders across three undefined binding thresholds.
metric
hit-rate
metric direction
higher
metric qualifier
designs confirmed as binders by BLI, out of designs selected for testing, as stated in Section 4.2; Section 2.4 prints 2.5% (5/201) for the same round
missing metadata
numerator: note: 3% of 201 is 6 against the 5 novel binders in Section 2.4.; reason: conflicting; uncertainty: note: No interval is printed.; reason: unreported
numeric value
3
printed value
3%
review
artifact sha256: 17039d69ecc37f45f6c402511b8f4497ce631003689fa95ad1ab221f8f787a4f; method: source-hash-verification; independent-cell-check; ai-assisted-source-review; method note: Re-downloaded (HTTP 200, 493,217 bytes, the same byte count as the pinned retrieval) but the SHA-256 differs, as expected for a mutable bioRxiv page whose hash describes one retrieval. Every extracted value and every quoted sentence was then located verbatim in the new retrieval, so the difference is in page furniture and not in the evidence. One section attribution and one quotation were corrected.; note: Reviewed in docs/reviews/use-cases/binder-2026-10-22.md. Automated AI review of the source transcription only; it is not human scientific review and nothing here was reproduced experimentally.; retrieval url: https://www.biorxiv.org/content/10.1101/2025.04.17.648362v1.full; reviewed at: 2026-10-22T15:00:00Z; reviewer: claude; reviewer note: Claude review agent, independent of the extraction agent; no human review claimed
source discrepancy
Section 2.4 prints 2.5% (5/201) for round 1 and Section 4.2 prints 3%. Both are recorded.
source locator
Section 4.1: 'from 3% in the first round to 13% (Figure 8)'
unit
percent
unit detail
percent of designs selected for testing
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