Result

NA directional-false-discovery-rate-at-100

debrouwer2026-biomni-a1-claude-4-post-cutoff directional-false-discovery-rate-at-100

Tested configuration: Biomni A1 (Claude 4) (AssayBench)
Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen
Dataset: AssayBench post-cutoff cohort of human CRISPR screens
Procedure: tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking
Evaluation: Biomni A1 (Claude 4) on the AssayBench post-cutoff cohort
Coverage: Not reported scored / Not reported eligible
Uncertainty: Not reported by the source
Evidence: Independent external evaluation · source checkedAssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'Biomni A1 (Claude 4)' cohort 'LaTest', column 'dFDR@100'

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split: Temporal split, post-cutoff cohort
Adaptation: biomedical agent with tool access, Claude 4 backbone
Scoring implementation: AnDCG@100, Precision@100 and dFDR@100 as defined in section 3

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-10-10-6e93f504adfc
Property and statement	Original source and location	Review and provenance
Reported result NA Individual claims	AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents Original source ↗ Table 3, row 'Biomni A1 (Claude 4)' cohort 'LaTest', column 'dFDR@100' Version: arXiv:2605.10876 version 1, posted 2026-05-11; not peer reviewed Retrieved: 2026-10-09T20:56:07Z	source checked ["source-hash-verification","pdf-text-parse","independent-cell-check"] · 2026-10-09T21:22:54Z independent paper Audit details Extracted by deterministic parse of the PDF text layer (pdftotext -layout) of Table 3, asserting the column header, 45 rows, 15 systems, the three cohorts per system and that dFDR is NA only for the post-cutoff cohort. Independent review 2026-10-09: value, metric, unit, direction, locator and configuration, protocol and dataset identity match the source. Field: `attributes.printed_value` Source artifact SHA-256: `805b402c28e0daa186415af202e04df56bf0cd7c7b1f872a6db170ee3c6c623d` Hash scope: pdftotext -layout text layer, parsed by extract/extract_target_validation.py Inspected artifact Extraction artifact SHA-256: `805b402c28e0daa186415af202e04df56bf0cd7c7b1f872a6db170ee3c6c623d` Extraction artifact

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Sources and history

Release 2026-10-10-6e93f504adfc · Record review: source checked

1 source records and release history

AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Original source · arXiv:2605.10876 version 1, posted 2026-05-11; not peer reviewed

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Technical metadata and extraction receipts

Stable ID: tgtval-20261009-result-debrouwer2026-biomni-a1-claude-4-post-cutoff-directional-false-discovery-rate-at-100

metric: directional-false-discovery-rate-at-100
metric qualifier: post-cutoff cohort; mean over benchmark entries
metric direction: lower
unit: fraction
printed value: NA
numeric value: Not reported
source locator: Table 3, row 'Biomni A1 (Claude 4)' cohort 'LaTest', column 'dFDR@100'
review: method: source-hash-verification; pdf-text-parse; independent-cell-check; method note: Re-downloaded the PDF and matched its SHA-256. Converted with pdftotext -layout and parsed Table 3 with a separate script written for this review, asserting the header and 48 rows. Checked printed and numeric value, metric, qualifier, unit, direction, locator, and the linked configuration, protocol and cohort dataset.; reviewer: claude; reviewer note: Separate Claude review agent, independent of the extractor; no human review claimed; reviewed at: 2026-10-09T21:22:54Z; artifact sha256: 805b402c28e0daa186415af202e04df56bf0cd7c7b1f872a6db170ee3c6c623d; retrieval url: https://arxiv.org/pdf/2605.10876v1; note: Extracted by deterministic parse of the PDF text layer (pdftotext -layout) of Table 3, asserting the column header, 45 rows, 15 systems, the three cohorts per system and that dFDR is NA only for the post-cutoff cohort. Independent review 2026-10-09: value, metric, unit, direction, locator and configuration, protocol and dataset identity match the source.
missing metadata: uncertainty: reason: unreported; value: reason: inapplicable; note: Printed NA: no screen in this cohort has negative relevance scores (Table 3 caption)

Related records

evaluation: Biomni A1 (Claude 4) on the AssayBench post-cutoff cohort

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