rewirebio.iobenchmarks
Result

0.76 f1-score

tamura2026-trinityfusion-c-driver-conventional f1-score (driver fusions, conventional RNA-seq of cell lines)

Tested configuration
TrinityFusion-C v0.3.4 (Tamura et al. 2026)
Protocol
Driver fusions, conventional RNA-seq of haematologic cell lines, validated truth (Tamura et al. 2026 Supplementary Table 5)
Dataset
CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
Procedure
rna-fusion-20261009-protocol-tamura2026-driver-conventional
Evaluation
TrinityFusion-C on driver fusions, conventional RNA-seq (Tamura et al. 2026)
Coverage
Not reported scored / Not reported eligible
Uncertainty
Not reported by the source
Evidence
Independent external evaluation · source checkedComparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'TrinityFusion-C', column 'F1' (PDF page text)

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split
All cell lines
Adaptation
Not reported
Scoring implementation
Gene pair and orientation match after HGNC alias resolution (Methods)

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

2 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-ba02f2f4a36e
Property and statementOriginal source and locationReview and provenance
Reported result
0.76
Individual claims
Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies

Original source ↗

Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'TrinityFusion-C', column 'F1' (PDF page text)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NPJ Precision Oncology 10:199, published 2026-04-04; PMC13230599 full-text XML
Retrieved: 2026-10-09T20:37:17Z

source checked

["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09

independent paper

Audit details

Extracted by deterministic parse of the pinned supplementary PDF text layer (pdftotext version 26.08.0, -layout) in extract/extract_rna_fusion.py, with table titles, sub-table headings, column headers and algorithm labels asserted. printed_value is the cell as printed, including thousands separators. Pending independent review. Independent review 2026-10-09: value and identity match the source.

Field: attributes.printed_value

Source artifact SHA-256: 540cf971970ad98557f3d4511f09c3f06a1b4359fe9276a25e29e731e36c0fc1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Extraction artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Extraction artifact

Reported result
0.76
Individual claims
Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12)

Original source ↗

Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'TrinityFusion-C', column 'F1' (PDF page text)

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41698_2026_1397_MOESM1_ESM.pdf as served by the publisher
Retrieved: 2026-10-09T20:37:37Z

source checked

["source-hash-verification","deterministic-table-parse","independent-cell-check"] · 2026-10-09

independent paper

Audit details

Extracted by deterministic parse of the pinned supplementary PDF text layer (pdftotext version 26.08.0, -layout) in extract/extract_rna_fusion.py, with table titles, sub-table headings, column headers and algorithm labels asserted. printed_value is the cell as printed, including thousands separators. Pending independent review. Independent review 2026-10-09: value and identity match the source.

Field: attributes.printed_value

Source artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Extraction artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Extraction artifact

Sources and history

Release 2026-10-09-ba02f2f4a36e · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: rna-fusion-20261009-result-tamura2026-trinityfusion-c-driver-conventional-f1-score

metric
f1-score
metric direction
higher
unit
fraction
metric qualifier
driver fusions, conventional RNA-seq of cell lines
printed value
0.76
source locator
Supplementary Table 5, 'Conventional RNA-seq of cell lines', row 'TrinityFusion-C', column 'F1' (PDF page text)
missing metadata
uncertainty: reason: unreported
review
method: source-hash-verification; deterministic-table-parse; independent-cell-check; method note: Re-downloaded the supplementary PDF and matched its SHA-256. Read the text layer with pdftotext -layout and a separate row parser written for this review (the extractor's script was not imported or run). Checked printed and numeric value, metric, qualifier, unit and direction from the table, sub-table and column, the algorithm label and the linked configuration and protocol. TPR, PPV and F1 were recomputed from TP, FP and FN (all within rounding), and TP plus FN equals the printed truth-set size or the driver truth count on every row.; reviewer: claude; reviewer note: Separate Claude review agent, independent of the extractor; no human review claimed; date: 2026-10-09; artifact sha256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275; retrieval url: https://static-content.springer.com/esm/art%3A10.1038%2Fs41698-026-01397-y/MediaObjects/41698_2026_1397_MOESM1_ESM.pdf; note: Extracted by deterministic parse of the pinned supplementary PDF text layer (pdftotext version 26.08.0, -layout) in extract/extract_rna_fusion.py, with table titles, sub-table headings, column headers and algorithm labels asserted. printed_value is the cell as printed, including thousands separators. Pending independent review. Independent review 2026-10-09: value and identity match the source.
numeric value
0.76
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