4.612 ± 0.317 AUSPC
Mean baseline · PertEval-scFM Norman single-gene (2,000 HVGs) AUSPC · Area Under the SPECTRA Performance Curve
- Tested configuration
- Mean baseline (context mean, no perturbation-specific effect)
- Protocol
- PertEval-scFM Norman single-gene (2,000 HVGs) AUSPC across SPECTRA sparsification splits
- Dataset subset
- Norman et al. 2019 single-gene perturbations, K562, top 2,000 HVGs (PertEval-scFM Table 1)
- Procedure
- Trapezoidal-rule AUSPC of MSE, scored on the perturbation-effect delta=P-Xc (Eq. 5), across seven SPECTRA sparsification splits (s=0.1..0.7), Norman single-gene, 2,000 HVGs.
- Evaluation
- Mean baseline on PertEval-scFM Norman single-gene (2,000 HVGs) AUSPC
- Coverage
- scored: unreported; eligible: unreported
- Uncertainty
- type: author_reported_propagated_standard_error; reported spread: 0.317; note: The source describes this quantity as a standard error (main-text Figure 2 caption: 'Average AUSPC (down-arrow) across sparsification probabilities for each model with standard error bars') and separately gives its own propagation formula (Appendix F.2, Eqs. F3-F5): AUSPC's uncertainty is derived from each split's own MSE uncertainty via the trapezoidal integral's partial derivatives (sigma^2 = sum_i (d/2)^2 * sigma_phi_i^2, where d=0.1 is the fixed sparsification step size). These two author statements describe the same quantity and are not in conflict: a propagated quantity can correctly be reported as a standard error. This is recorded as the author's own reported, propagated uncertainty; the F3-F5 derivation is the authors' own formula and its mathematical correctness has not been independently validated here. It must not be read as an independently resampled model-seed standard deviation or a confidence interval. The underlying per-split uncertainty is attributed by the source to triplicate experiments per model (Appendix I, Figure I1 caption: 'Experiments were carried out in triplicate for each model'), not to the main-text Figure 2 region. Figure I1's own caption separately states '8 train-test splits of increasing difficulty' for this same Norman single-gene evaluation, while Table 1 prints seven S-columns (S0.1-S0.7) and Appendix F.2 describes the sparsification probabilities as spanning 0.1 to 0.7. This 7-vs-8 discrepancy between the Figure I1 caption and the Table 1 / F.2 grid is preserved exactly as printed, not resolved; it must not be read as establishing an eighth Table 1 column or a confirmed n_runs=7, and no significance claim is made from any overlapping error bars.
- Evidence
- Author-reported evaluation · source checkedPertEval-scFM (Wenteler et al., ICML 2025), full text · Table 1, Norman single-gene section, row Mean baseline, column AUSPC (10^-2).
A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.
Reproduction
- Split
- Not reported
- Adaptation
- Not reported
- Scoring implementation
- AUSPC (trapezoidal-rule integral of MSE across seven SPECTRA sparsification-probability train-test splits, s=0.1..0.7; Appendix F.2 Eq. F2)
No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.
Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
1 evidence row matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Reported result 4.612 ± 0.317 Individual claims | PertEval-scFM (Wenteler et al., ICML 2025), full text Table 1, Norman single-gene section, row Mean baseline, column AUSPC (10^-2). Version: PMLR v267 wenteler25a (as served by the PMLR-affiliated mlresearch/v267 GitHub mirror; ETag "ed9f0fe44cf6edc939ee6950d024f65dcd8dd6f16414bd9f5297cda9395d6e58" at retrieval) | source checked Exact printed value transcribed from the primary PDF (pdftotext -layout extraction), independently checked against the rendered table text twice in this session. Not model execution. · 2026-10-07 author reported Audit detailsSource checked, not reproduced. Rank 6th of eight Table 1 configurations by this metric in the source's own printed rank column (the '-' in the adjacent Delta-AUSPC column marks this row as the reference baseline that Delta-AUSPC is computed against, not a missing rank; Rank itself is printed as 6); only three of eight rows are intaken. Field: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: |
Sources and history
View linked audit checks and correction history
Release 2026-10-07-1448159e6a81 · Record review: source checked
1 source records and release history
- PertEval-scFM (Wenteler et al., ICML 2025), full text · Original source · PMLR v267 wenteler25a (as served by the PMLR-affiliated mlresearch/v267 GitHub mirror; ETag "ed9f0fe44cf6edc939ee6950d024f65dcd8dd6f16414bd9f5297cda9395d6e58" at retrieval)
Technical metadata and extraction receipts
Stable ID: perteval-scfm-2025-result-mean-baseline-auspc
- areas
- cells-spatial-multiomics
- tasks
- Norman single-gene perturbation effect prediction, 2,000 HVGs, SPECTRA distribution shift
- metric
- AUSPC
- metric direction
- lower
- unit
- 10^-2 (printed column header units)
- printed value
- 4.612 ± 0.317
- numeric value
- 4.612
- derived normalized value
- 0.04612
- derived normalized value note
- 4.612 x 10^-2, computed here for cross-scale comparability only; not a separate printed source value.
- uncertainty
- type: author_reported_propagated_standard_error; reported spread: 0.317; note: The source describes this quantity as a standard error (main-text Figure 2 caption: 'Average AUSPC (down-arrow) across sparsification probabilities for each model with standard error bars') and separately gives its own propagation formula (Appendix F.2, Eqs. F3-F5): AUSPC's uncertainty is derived from each split's own MSE uncertainty via the trapezoidal integral's partial derivatives (sigma^2 = sum_i (d/2)^2 * sigma_phi_i^2, where d=0.1 is the fixed sparsification step size). These two author statements describe the same quantity and are not in conflict: a propagated quantity can correctly be reported as a standard error. This is recorded as the author's own reported, propagated uncertainty; the F3-F5 derivation is the authors' own formula and its mathematical correctness has not been independently validated here. It must not be read as an independently resampled model-seed standard deviation or a confidence interval. The underlying per-split uncertainty is attributed by the source to triplicate experiments per model (Appendix I, Figure I1 caption: 'Experiments were carried out in triplicate for each model'), not to the main-text Figure 2 region. Figure I1's own caption separately states '8 train-test splits of increasing difficulty' for this same Norman single-gene evaluation, while Table 1 prints seven S-columns (S0.1-S0.7) and Appendix F.2 describes the sparsification probabilities as spanning 0.1 to 0.7. This 7-vs-8 discrepancy between the Figure I1 caption and the Table 1 / F.2 grid is preserved exactly as printed, not resolved; it must not be read as establishing an eighth Table 1 column or a confirmed n_runs=7, and no significance claim is made from any overlapping error bars.
- source locator
- Table 1, Norman single-gene section, row Mean baseline, column AUSPC (10^-2).
- review
- method: Exact printed value transcribed from the primary PDF (pdftotext -layout extraction), independently checked against the rendered table text twice in this session. Not model execution.; reviewer: Claude (local extraction, this session), with corrections independently identified by a separate Codex review pass before this intake; date: 2026-10-07; artifact sha256: c116a153872645d5c91b9ee836df3945cd8ffd02a6e736f58f854c4b70978bcc; retrieval url: https://raw.githubusercontent.com/mlresearch/v267/main/assets/wenteler25a/wenteler25a.pdf; notes: Source checked, not reproduced. Rank 6th of eight Table 1 configurations by this metric in the source's own printed rank column (the '-' in the adjacent Delta-AUSPC column marks this row as the reference baseline that Delta-AUSPC is computed against, not a missing rank; Rank itself is printed as 6); only three of eight rows are intaken.
- evidence overlap
- Independent of the GEARS Supplementary Table 6 catalogue entries for this use case. This is the protocol's own Mean-baseline reference row, distinct from Table 6's 'No Perturb' control.