Result

Pearson of Boltz-2 on SARS-CoV-2 Mpro ligands

0.8 Pearson

Methods

Tested configuration: Boltz-2
Task: Ligand potency prediction using generated poses
Dataset: SARS-CoV-2 Mpro ligands
Related family profiles: Boltz-2
Procedure: Potency prediction using Boltz-2 ligand-pose generation protocol; see paper scoring pipeline.
Evaluation: Boltz-2: Ligand potency prediction using generated poses
Coverage: Not reported scored / Not reported eligible
Uncertainty: ± 0.027 (type not stated)
Evidence: Independent external evaluation · source checkedA Comparative Study of Deep Learning and Classical Modeling Approaches for Protein–Ligand Binding Pose and Affinity Prediction in Coronavirus Main Proteases · Table 3, Boltz-2 row, Pearson’s R column

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Reproduction

Split: Not reported
Adaptation: Not reported
Scoring implementation: Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

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1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statement	Original source and location	Review and provenance
Printed value 0.800 Individual claims	A Comparative Study of Deep Learning and Classical Modeling Approaches for Protein–Ligand Binding Pose and Affinity Prediction in Coronavirus Main Proteases Original source ↗ Table 3, Boltz-2 row, Pearson’s R column Version: version of record Retrieved: 2026-09-16T10:41:16.557756+00:00	source checked ["ai-assisted-source-review"] · 2026-09-16T10:41:16.557756+00:00 independent paper Audit details JATS label is bare 3. Selected SARS-CoV-2 Mpro potency Pearson R, not MERS-CoV table 2 or Boltz-2-Internal row; uncertainty retained in evidence. This verifies the central score at its source location, not every metadata field or an experimental reproduction. Field: `attributes.printed_value` Claim: claim-lit-047 Source artifact SHA-256: `c356a1c65a0033e5ae18a05d4afab5495856c5b6869328ff49e13547a4801a57` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact Extraction artifact SHA-256: `c356a1c65a0033e5ae18a05d4afab5495856c5b6869328ff49e13547a4801a57` Extraction artifact

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Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release history

A Comparative Study of Deep Learning and Classical Modeling Approaches for Protein–Ligand Binding Pose and Affinity Prediction in Coronavirus Main Proteases · Original source · version of record

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Technical metadata and extraction receipts

Stable ID: lit-047

areas: molecular-interactions
tasks: Ligand potency prediction using generated poses
printed value: 0.800
numeric value: 0.800
metric: pearson-correlation
metric direction: unknown
unit: unitless
uncertainty: type: unresolved_spread; printed: ± 0.027; value: 0.027
source locator: Table 3, Boltz-2 row, Pearson’s R column
review: method: ai-assisted-source-review; reviewer: codex; reviewed at: 2026-09-16T10:41:16.557756+00:00; evidence: {"table_xml_id": "tbl3", "row_cells": ["Boltz-2", "0.716 ± 0.036", "0.909 ± 0.043", "0.800 ± 0.027", "9.54 × 10–59", "0.532 ± 0.043", "0.598 ± 0.024", "0.799 ± 0.012"], "selected_cell_zero_based": 3, "selected_cell_xml": "<td align=\"center\" colspan=\"1\" rowspan=\"1\">0.800 ± 0.027</td>", "caption": "Statistical Performance Metrics of Potency Prediction for SARS-CoV-2 Mpro Using Different Ligand Pose Generation Protocols"}; artifact sha256: c356a1c65a0033e5ae18a05d4afab5495856c5b6869328ff49e13547a4801a57; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12801289/fullTextXML; method note: independent; table-level review; reviewer note: role: omics research agent; independent source-table review; not human review; note: JATS label is bare 3. Selected SARS-CoV-2 Mpro potency Pearson R, not MERS-CoV table 2 or Boltz-2-Internal row; uncertainty retained in evidence. This verifies the central score at its source location, not every metadata field or an experimental reproduction.
legacy id: lit-047
missing metadata: dataset version: reason: unextracted; model version: reason: unextracted; split: reason: unextracted

Related records

evaluation: Boltz-2: Ligand potency prediction using generated poses
subject: Reported Pearson R for Boltz-2

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