Result

0.8 Pearson R

Boltz-2 · Pearson R · SARS-CoV-2 Mpro ligands

Tested configuration: Boltz-2
Task: Ligand potency prediction using generated poses
Dataset: SARS-CoV-2 Mpro ligands
Related family profiles: Boltz-2
Procedure: Potency prediction using Boltz-2 ligand-pose generation protocol; see paper scoring pipeline.
Evaluation: Boltz-2: Ligand potency prediction using generated poses
Coverage: scored: unreported; eligible: unreported
Uncertainty: ± 0.027
Evidence: Independent external evaluation · source checkedA Comparative Study of Deep Learning and Classical Modeling Approaches for Protein–Ligand Binding Pose and Affinity Prediction in Coronavirus Main Proteases · Table 3, Boltz-2 row, Pearson’s R column

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Reproduction

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Adaptation: Not reported
Scoring implementation: Not reported

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Evidence

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1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statement	Original source and location	Review and provenance
attributes.printed_value 0.800 Individual claims	A Comparative Study of Deep Learning and Classical Modeling Approaches for Protein–Ligand Binding Pose and Affinity Prediction in Coronavirus Main Proteases Original source ↗ Table 3, Boltz-2 row, Pearson’s R column Version: version of record Retrieved: 2026-09-16T10:41:16.557756+00:00	source checked independent ai table review · 2026-09-16T10:41:16.557756+00:00 independent paper Audit details JATS label is bare 3. Selected SARS-CoV-2 Mpro potency Pearson R, not MERS-CoV table 2 or Boltz-2-Internal row; uncertainty retained in evidence. This verifies the central score at its source location, not every metadata field or an experimental reproduction. Field: `attributes.printed_value` Claim: claim-lit-047 Source artifact SHA-256: `c356a1c65a0033e5ae18a05d4afab5495856c5b6869328ff49e13547a4801a57` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact Extraction artifact SHA-256: `c356a1c65a0033e5ae18a05d4afab5495856c5b6869328ff49e13547a4801a57` Extraction artifact

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Release 2026-09-29-06401fd5b220 · Record review: source checked

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A Comparative Study of Deep Learning and Classical Modeling Approaches for Protein–Ligand Binding Pose and Affinity Prediction in Coronavirus Main Proteases · Original source · version of record

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Technical metadata and extraction receipts

Stable ID: lit-047

areas: molecular-interactions
tasks: Ligand potency prediction using generated poses
printed value: 0.800
numeric value: 0.800
metric: Pearson R
metric direction: unknown
unit: unitless
uncertainty: ± 0.027
source locator: Table 3, Boltz-2 row, Pearson’s R column
review: method: independent_ai_table_review; reviewer: Codex omics research agent; independent source-table review, not human review; reviewed at: 2026-09-16T10:41:16.557756+00:00; notes: JATS label is bare 3. Selected SARS-CoV-2 Mpro potency Pearson R, not MERS-CoV table 2 or Boltz-2-Internal row; uncertainty retained in evidence. This verifies the central score at its source location, not every metadata field or an experimental reproduction.; evidence: {"table_xml_id": "tbl3", "row_cells": ["Boltz-2", "0.716 ± 0.036", "0.909 ± 0.043", "0.800 ± 0.027", "9.54 × 10–59", "0.532 ± 0.043", "0.598 ± 0.024", "0.799 ± 0.012"], "selected_cell_zero_based": 3, "selected_cell_xml": "<td align=\"center\" colspan=\"1\" rowspan=\"1\">0.800 ± 0.027</td>", "caption": "Statistical Performance Metrics of Potency Prediction for SARS-CoV-2 Mpro Using Different Ligand Pose Generation Protocols"}; artifact sha256: c356a1c65a0033e5ae18a05d4afab5495856c5b6869328ff49e13547a4801a57; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12801289/fullTextXML
legacy id: lit-047
legacy row: id: lit-047; paper id: mpro-pose-affinity-2025; domain id: molecular-interactions; task: Ligand potency prediction using generated poses; model: Boltz-2; model version: Not reported; dataset: SARS-CoV-2 Mpro ligands; dataset version: Not reported; split: Not reported; metric: Pearson R; value: 0.800; unit: unitless; uncertainty: ± 0.027; protocol: Potency prediction using Boltz-2 ligand-pose generation protocol; see paper scoring pipeline.; source locator: Table 3, Boltz-2 row, Pearson’s R column; source url: https://pmc.ncbi.nlm.nih.gov/articles/PMC12801289/; evaluation origin: independent_paper; reviewed utc: 2026-09-15T23:25:00Z
missing metadata: model version: not_reported_in_legacy_extract; dataset version: not_reported_in_legacy_extract; split: not_reported_in_legacy_extract

Related records

evaluation: Boltz-2: Ligand potency prediction using generated poses
subject: Reported Pearson R for Boltz-2

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