Result

Bedroc (BEDROC with alpha = 80.5, mean over the 81 DEKOIS 2.0 targets) of SurfDock on DEKOIS 2.0, values quoted by Shen et al. 2025 on DEKOIS 2.0, 79 targets as scored by Shen et al. 2025

0.488 Bedroc (BEDROC with alpha = 80.5, mean over the 81 DEKOIS 2.0 targets)

Methods

Tested configuration: SurfDock on DEKOIS 2.0, values quoted by Shen et al. 2025
Protocol: DEKOIS 2.0 screening with co-folding confidence scores against docking tools (Shen et al. 2025 Table 1)
Dataset: DEKOIS 2.0, 79 targets as scored by Shen et al. 2025
Procedure: DEKOIS 2.0 screening with co-folding confidence scores against docking tools (Shen et al. 2025 Table 1)
Evaluation: SurfDock on DEKOIS 2.0 (Shen et al. 2025 Table 1)
Coverage: Not reported scored / Not reported eligible
Uncertainty: Not reported by the source: The source prints no interval or spread for this value
Evidence: Result quoted from another source · source checkedShen et al. 2025, Chemical Science (Europe PMC full text) · Table 1, row 'SurfDockf', column 'BEDROC (α = 80.5)' (Mean)

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split: All 81 DEKOIS 2.0 targets
Adaptation: None; pretrained models and default or recommended settings
Scoring implementation: AUROC, BEDROC with alpha = 80.5 (the top 2% of the ranked list contributes 80% of the score), and enrichment factors at 0.5%, 1% and 5%, each reported as the mean and the median over targets. EFx% is the ratio of true positives found in the top x% of the ranked compounds relative to random selection.

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Reported result 0.488 Individual claims	Shen et al. 2025, Chemical Science (Europe PMC full text) Original source ↗ Table 1, row 'SurfDockf', column 'BEDROC (α = 80.5)' (Mean) Version: PMC12704515 (Chem Sci, published 2025-12-11) Retrieved: 2026-10-22T11:52:32Z	source checked ["independent-cell-check","deterministic-table-parse"] · 2026-10-22 paper compilation Audit details Checked against the pinned source by an automated independent re-parse. Transcription checked; not reproduced and not reviewed by a human scientist. Field: `attributes.printed_value` Source artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Hash scope: Hash scope not separately documented; inspect source record Extraction artifact SHA-256: `11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8` Extraction artifact

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release history

Shen et al. 2025, Chemical Science (Europe PMC full text) · Original source · PMC12704515 (Chem Sci, published 2025-12-11)

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Technical metadata and extraction receipts

Stable ID: hitdisc-20261022-result-dekois-builtin-quoted-surfdock-dekois-bedroc-bedrocalpha80p5-mean

metric: bedroc
metric direction: higher
unit: unitless
metric qualifier: BEDROC with alpha = 80.5, mean over the 81 DEKOIS 2.0 targets
printed value: 0.488
numeric value: 0.488
source locator: Table 1, row 'SurfDockf', column 'BEDROC (α = 80.5)' (Mean)
missing metadata: uncertainty: reason: unreported; note: The source prints no interval or spread for this value
review: method: independent-cell-check; deterministic-table-parse; reviewer: claude; reviewer note: Claude review agent, independent of the extraction agent; no human review claimed; date: 2026-10-22; method note: Re-downloaded the pinned Europe PMC XML, matched its SHA-256, and re-parsed Tables 1 to 5 with a parser written for this review (myparse_shen.py), independent of the extractor's build_batch.py. Every printed value, row label and column header compared; the parser was proved on six seeded errors.; note: Checked against the pinned source by an automated independent re-parse. Transcription checked; not reproduced and not reviewed by a human scientist.; artifact sha256: 11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8; retrieval url: https://www.ebi.ac.uk/europepmc/webservices/rest/PMC12704515/fullTextXML; receipt: data/omics/use-case-coverage-hitdisc-20261022/review.json
source table: Table 1
source warnings: Printed with footnote f (ref. 36), 81 targets.
scope note: Calculated on all 81 targets, not the 79 used by the other rows (footnote f).

Related records

evaluation: SurfDock on DEKOIS 2.0 (Shen et al. 2025 Table 1)

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