rewirebio.iobenchmarks
Result

AUPRC (maximum over three random seeds; zero-shot) of GPN-MSA ablation 'Window size = 16' (Supplementary Table 4) on COSMIC frequent vs gnomAD common missense variants (GPN-MSA paper)

0.25 AUPRC (maximum over three random seeds; zero-shot)

Methods

Tested configuration
GPN-MSA ablation 'Window size = 16' (Supplementary Table 4)
Protocol
COSMIC frequent vs gnomAD common missense, AUPRC (GPN-MSA Supplementary Table 4)
Dataset
COSMIC frequent vs gnomAD common missense variants (GPN-MSA paper)
Procedure
COSMIC frequent vs gnomAD common missense, AUPRC (GPN-MSA Supplementary Table 4)
Evaluation
Window size = 16 on COSMIC (GPN-MSA Supplementary Table 4)
Coverage
Not reported scored / Not reported eligible
Uncertainty
Not reported by the source: Only mean and max over seeds are printed
Evidence
Author-reported evaluation · source checkedGPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2) · Supplementary Table 4 (PDF page 23), row 'Window size = 16', column 'COSMIC' / 'max'

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: source checked. Source checked does not mean independently reproduced.

Reproduction

Split
Whole labelled set
Adaptation
zero-shot
Scoring implementation
Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Reported result
0.250
Individual claims
GPN-MSA: an alignment-based DNA language model for genome-wide variant effect prediction (bioRxiv v2)

Original source ↗

Supplementary Table 4 (PDF page 23), row 'Window size = 16', column 'COSMIC' / 'max'

Version: bioRxiv v2, posted 2024-04-06
Retrieved: 2026-10-14T12:02:16Z

source checked

["source-hash-verification","pdf-text-parse","independent-cell-check"] · 2026-10-14

author reported

Audit details

Extraction: Parsed the pdftotext 26.08.0 -layout text of the pinned PDF with extract/build_gpnmsa.py; header groups, 'mean max' header, the 17 row labels and the page are asserted. Independent review 2026-10-14: matched.

Field: attributes.printed_value

Source artifact SHA-256: 10411077df1ae59614f9a9a9f85384103d54127ba67a9b3c469a4a2d6c33cee4

Hash scope: SHA-256 of the PDF bytes as downloaded 2026-10-14T12:02:16Z. bioRxiv rewrites the XMP dates and document IDs, the Info ModDate and the trailer /ID on download, so a re-download does not reproduce the hash; the review found a fresh copy of the same length differing only in those 51 bytes, with an identical pdftotext -layout text layer.

Inspected artifact

Extraction artifact SHA-256: 10411077df1ae59614f9a9a9f85384103d54127ba67a9b3c469a4a2d6c33cee4

Extraction artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: gfm-guides-20261014-gpnmsa-result-ablation-window-16-cosmic-max

printed value
0.250
numeric value
0.250
metric
auprc
metric direction
higher
unit
unitless
metric qualifier
maximum over three random seeds; zero-shot
source locator
Supplementary Table 4 (PDF page 23), row 'Window size = 16', column 'COSMIC' / 'max'
missing metadata
uncertainty: reason: unreported; note: Only mean and max over seeds are printed
review
method: source-hash-verification; pdf-text-parse; independent-cell-check; method note: An independent parser of the pdftotext layer of the pinned PDF read all 17 rows of Supplementary Table 4 and matched all 102 results (value, metric, mean or max, protocol, one configuration or method per row). Six cells also checked by hand.; reviewer: claude; reviewer note: Claude (Opus 5.5) research agent, independent of the extractor; no human review claimed; date: 2026-10-14; artifact sha256: 10411077df1ae59614f9a9a9f85384103d54127ba67a9b3c469a4a2d6c33cee4; retrieval url: https://www.biorxiv.org/content/10.1101/2023.10.10.561776v2.full.pdf; note: Extraction: Parsed the pdftotext 26.08.0 -layout text of the pinned PDF with extract/build_gpnmsa.py; header groups, 'mean max' header, the 17 row labels and the page are asserted. Independent review 2026-10-14: matched.
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