Result

0.507 auPRC

Splam (paper Table 3): Human splice-junction classification and count prediction, auPRC

Tested configuration: Splam (paper Table 3)
Protocol: Human splice-junction classification and count prediction (AlphaGenome paper)
Dataset subset: Human splice-junction classification and count prediction: evaluated data subset
Procedure: For classification, contrast read-supported junctions with unobserved donor–acceptor pairs. For count prediction, correlate log(1+x)-transformed predicted and observed counts only on nonzero observed junctions.
Evaluation: Splam (paper Table 3): Human splice-junction classification and count prediction
Coverage: scored: unreported; eligible: unreported
Uncertainty: Not reported
Evidence: Author-reported evaluation · source checkedAlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!J9

A source-checked result verifies the numerical transcription, not every model or protocol detail. Evaluation metadata: needs review. Source checked does not mean independently reproduced.

Reproduction

Split: Held-out intervals of fold-1 evaluated with a model ensemble trained on fold-1 training data.
Adaptation: Splam (paper Table 3)
Scoring implementation: Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Access requirements and official instructions: Human splice-junction classification and count prediction (AlphaGenome paper)

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

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Evidence table

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1 evidence row matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statement	Original source and location	Review and provenance
Reported result 0.507 Individual claims	AlphaGenome Nature 2026 supplementary comparison tables Original source ↗ 'Suppl Table 3 Track performance'!J9 Version: Nature version of record, 28 January 2026 Retrieved: 2026-09-17T06:31:06.887921+00:00	source checked OOXML extraction and separate automated primary-source review · 2026-09-17 author reported Audit details Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun. Field: `attributes.printed_value` Source artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Hash scope: SHA-256 of exact retrieved original artifact bytes Format: xlsx Inspected artifact Extraction artifact SHA-256: `833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154` Extraction artifact

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Sources and history

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Release 2026-09-29-06401fd5b220 · Record review: source checked

3 source records and release history

AlphaGenome Nature 2026 supplementary comparison tables · Original source · Nature version of record, 28 January 2026
AlphaGenome Nature 2026 supplementary methods · Original source · Supplement to Nature version of record, 28 January 2026; content hash pinned
alphagenome: Journal full-text XML · Original source · Retrieved page snapshot; no immutable publisher revision supplied

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Technical metadata and extraction receipts

Stable ID: alphagenome-2026-result-daa1483eb13a0b15

areas: dna-genomes
printed value: 0.507
printed value basis: Workbook number format 0.000
numeric value: 0.50700000000000001
raw xml value: 0.50700000000000001
workbook number format: 0.000
metric: auPRC
metric direction: higher
unit: dimensionless
aggregation: Classification: auPRC per tissue averaged across tissues. Quantitative endpoint: Pearson correlation of log-transformed counts; do not pool these two metric rows.
uncertainty: Not reported
scored count: Not reported
eligible count: Not reported
source cells: 'Suppl Table 3 Track performance'!J9
source locator: 'Suppl Table 3 Track performance'!J9
review: method: OOXML extraction and separate automated primary-source review; date: 2026-09-17; artifact sha256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154; retrieval url: https://media.springernature.com/original/springer-static/esm/art%3A10.1038%2Fs41586-025-10014-0/MediaObjects/41586_2025_10014_MOESM3_ESM.xlsx; note: Checked against a second extraction. Fixed-format display and exact stored decimals preserved separately. No experiment rerun.
missing metadata: uncertainty: unreported; scored count: unextracted; eligible count: unextracted; seeds: unreported
source warnings: None recorded

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evaluation: Splam (paper Table 3): Human splice-junction classification and count prediction

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