Model

ESMFold

ESMFold predicts protein structures directly from amino-acid sequence using ESM-2 representations.

Sources (3)

facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config

14 evaluations · 14 results

How it worksESMFold workflow

Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation.

Sources (3)

Overview

Model type

Sequence-to-structure protein prediction pipeline

Inputs

Protein amino-acid sequence; the ESMFold interface also accepts chains separated by a colon.

Outputs

Predicted PDB structure and confidence values.

Access

Official project documentation and implementation: https://github.com/facebookresearch/esm

Sources (3)

limited source coverage · Automated source review, 2026-09-16. All specifications and missing details

Evaluations and results

14 evaluations · 14 results. Different protocols are not a single leaderboard.

Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)

Sorted by GDT ts (mean over targets) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.

Tested configuration	Protocol and dataset	GDT ts (mean over targets)	GDT ts (median over targets)	lDDT (mean over targets)	lDDT (median over targets)	Proteinbench ca break (mean over targets)	Proteinbench ca break (median over targets)	Proteinbench ca clash (mean over targets)	Proteinbench ca clash (median over targets)	Proteinbench pepbond break (mean over targets)	Proteinbench pepbond break (median over targets)	RMSD (mean over targets)	RMSD (median over targets)	TM score (mean over targets)	TM score (median over targets)
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-GDT-TS-MEAN: Accuracy GDT-TS (mean)	0.826	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-GDT-TS-MEDIAN: Accuracy GDT-TS (median)	Not reported	0.881	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-LDDT-MEAN: Accuracy lDDT (mean)	Not reported	Not reported	0.87	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-LDDT-MEDIAN: Accuracy lDDT (median)	Not reported	Not reported	Not reported	0.907	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-RMSD-MEAN: Accuracy RMSD (mean)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	3.98	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-RMSD-MEDIAN: Accuracy RMSD (median)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	2.1	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-TM-SCORE-MEAN: Accuracy TM-score (mean)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.847	Not reported
ESMFoldEvaluation	ProteinBench FOLD-ACCURACY-TM-SCORE-MEDIAN: Accuracy TM-score (median)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.929
ESMFoldEvaluation	ProteinBench FOLD-QUALITY-CA-BREAK-MEAN: Quality CA break (%) (mean)	Not reported	Not reported	Not reported	Not reported	0%	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-QUALITY-CA-BREAK-MEDIAN: Quality CA break (%) (median)	Not reported	Not reported	Not reported	Not reported	Not reported	0%	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-QUALITY-CA-CLASH-MEAN: Quality CA clash (%) (mean)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0.3%	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-QUALITY-CA-CLASH-MEDIAN: Quality CA clash (%) (median)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	0%	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-QUALITY-PEPBOND-BREAK-MEAN: Quality PepBond break (%) (mean)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	4.7%	Not reported	Not reported	Not reported	Not reported	Not reported
ESMFoldEvaluation	ProteinBench FOLD-QUALITY-PEPBOND-BREAK-MEDIAN: Quality PepBond break (%) (median)	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	Not reported	3.4%	Not reported	Not reported	Not reported	Not reported

All 14 result rows with coverage, uncertainty and sources

Filter evaluations

Tested model or methodProtocolDatasetEvaluation setupMetricEvidence origin

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configuration	Protocol and dataset	Finding	Evidence and details
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-GDT-TS-MEAN: Accuracy GDT-TS (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.826 GDT ts (mean over targets) fraction · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-GDT-TS-MEAN: Accuracy GDT-TS (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy GDT-TS ↑)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-GDT-TS-MEDIAN: Accuracy GDT-TS (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.881 GDT ts (median over targets) fraction · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-GDT-TS-MEDIAN: Accuracy GDT-TS (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy GDT-TS ↑)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-LDDT-MEAN: Accuracy lDDT (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.87 lDDT (mean over targets) fraction · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-LDDT-MEAN: Accuracy lDDT (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy lDDT ↑)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-LDDT-MEDIAN: Accuracy lDDT (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.907 lDDT (median over targets) fraction · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-LDDT-MEDIAN: Accuracy lDDT (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy lDDT ↑)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-RMSD-MEAN: Accuracy RMSD (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	3.98 RMSD (mean over targets) unit-unreported · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-RMSD-MEAN: Accuracy RMSD (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy RMSD ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-RMSD-MEDIAN: Accuracy RMSD (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	2.1 RMSD (median over targets) unit-unreported · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-RMSD-MEDIAN: Accuracy RMSD (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy RMSD ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-TM-SCORE-MEAN: Accuracy TM-score (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.847 TM score (mean over targets) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-TM-SCORE-MEAN: Accuracy TM-score (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy TM-score ↑)
Configuration: ESMFold	Task: ProteinBench FOLD-ACCURACY-TM-SCORE-MEDIAN: Accuracy TM-score (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.929 TM score (median over targets) unitless · higher Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-ACCURACY-TM-SCORE-MEDIAN: Accuracy TM-score (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Accuracy TM-score ↑)
Configuration: ESMFold	Task: ProteinBench FOLD-QUALITY-CA-BREAK-MEAN: Quality CA break (%) (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0% Proteinbench ca break (mean over targets) percent · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-QUALITY-CA-BREAK-MEAN: Quality CA break (%) (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Quality CA break (%) ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-QUALITY-CA-BREAK-MEDIAN: Quality CA break (%) (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0% Proteinbench ca break (median over targets) percent · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-QUALITY-CA-BREAK-MEDIAN: Quality CA break (%) (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Quality CA break (%) ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-QUALITY-CA-CLASH-MEAN: Quality CA clash (%) (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0.3% Proteinbench ca clash (mean over targets) percent · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-QUALITY-CA-CLASH-MEAN: Quality CA clash (%) (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Quality CA clash (%) ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-QUALITY-CA-CLASH-MEDIAN: Quality CA clash (%) (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	0% Proteinbench ca clash (median over targets) percent · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-QUALITY-CA-CLASH-MEDIAN: Quality CA clash (%) (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Quality CA clash (%) ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-QUALITY-PEPBOND-BREAK-MEAN: Quality PepBond break (%) (mean) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	4.7% Proteinbench pepbond break (mean over targets) percent · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-QUALITY-PEPBOND-BREAK-MEAN: Quality PepBond break (%) (mean) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Quality PepBond break (%) ↓)
Configuration: ESMFold	Task: ProteinBench FOLD-QUALITY-PEPBOND-BREAK-MEDIAN: Quality PepBond break (%) (median) Dataset subset: CAMEO2022, 183 proteins (ProteinBench split)	3.4% Proteinbench pepbond break (median over targets) percent · lower Uncertainty: Not yet extracted Coverage: Not reported scored / Not reported eligible	Author-reported evaluation · Source checked Methods, coverage and source ESMFold on ProteinBench FOLD-QUALITY-PEPBOND-BREAK-MEDIAN: Quality PepBond break (%) (median) Structure prediction on CAMEO2022. Each cell prints the mean and the median over 183 proteins. Aggregation: Not reported proteinbench primary benchmark evidence · Table 7, row(ESMFold), column(Quality PepBond break (%) ↓)

Source checking is not independent reproduction. Release 2026-10-12-fcce59cc481b.

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How it works, versions and access

Related profile: ESMFold. This page retains the exact record and its evaluation context.

Versions and evaluated configurations

ESMFold · family

How it works

ESMFold predicts protein structures directly from amino-acid sequence using ESM-2 representations. ESM-2 sequence representations feed a folding trunk and structure module. The checked v1 configuration has 48 trunk blocks, eight structure-module blocks and up to four recycles. The documented inputs are protein amino-acid sequence; the ESMFold interface also accepts chains separated by a colon. The output consists of predicted PDB structure and confidence values.

Sources (3)

Versions and reproducibility

esmfold_v0 and esmfold_v1; v1 is the repository recommendation. Inference length is constrained by memory; the repository documents chunking and CPU offload. Backbone position settings do not alone establish the full folding pipeline limit.

Sources (3)

Strengths, limitations and unresolved questions

Strengths and limitations

Strengths and considerations

Supports sequence-only structure prediction without an MSA search.
Sources (3)
facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config

Limitations and conditions

ESMFold v0 and v1 are different releases. The repository discourages using structure-module-only ablation models as the standard predictor.
Sources (3)
facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config

Profile review details

Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied.

Stable record: catalog-model-esmfold

Specifications

Inputs, training, access and other details

Explanatory profile: limited source coverage · Automated source review, 2026-09-16. Review applies to the cited claims; unresolved fields are listed below. Numerical results retain their own review status.

Inputs, outputs and configuration
Property	Description and evidence
Model type	Sequence-to-structure protein prediction pipeline Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Architecture	ESM-2 sequence representations feed a folding trunk and structure module. The checked v1 configuration has 48 trunk blocks, eight structure-module blocks and up to four recycles. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Inputs	Protein amino-acid sequence; the ESMFold interface also accepts chains separated by a colon. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Outputs	Predicted PDB structure and confidence values. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Parameters	The released v1 configuration identifies an ESM-2 3B backbone plus a folding trunk and structure module. The 3B figure is not the total size of the complete predictor. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Known versions	esmfold_v0 and esmfold_v1; v1 is the repository recommendation. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Training data	PDB and UniRef50 are listed for ESMFold. Full structural training-cutoff verification remains outstanding. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Training cutoff	PDB and UniRef50 are identified in the official model table; the inspected ESMFold-v1 card and configuration do not supply a shared latest-data date for both components. · Not reported in inspected sources Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Context limits	Inference length is constrained by memory; the repository documents chunking and CPU offload. Backbone position settings do not alone establish the full folding pipeline limit. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Weights licence	MIT declared by the official facebook/esmfold_v1 model card. Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Access	Official project documentation and implementation: https://github.com/facebookresearch/esm Sources (3) facebookresearch/esm: README.md; facebook/esmfold_v1: README.md; facebook/esmfold_v1: config.json · ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config
Code licence	MIT Sources facebookresearch/esm: LICENSE · LICENSE: licence text

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

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63 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-12-fcce59cc481b
Property and statement	Original source and location	Review and provenance
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	facebookresearch/esm: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T19:46:19.090082+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	facebook/esmfold_v1: config.json Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 75a3841ee059df2bf4d56688166c8fb459ddd97a Retrieved: 2026-09-16T20:04:02.231029+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `6b98125e2685fef2875499f6bd7c83968a077993ab53f99bf5581113665f7cc6` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram caption Conceptual summary of the documented data flow; optional inputs and configured downstream stages must be reported for a reproducible evaluation. Individual claims	facebook/esmfold_v1: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 75a3841ee059df2bf4d56688166c8fb459ddd97a Retrieved: 2026-09-16T20:04:02.231029+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.caption` Source artifact SHA-256: `12c535c3711211dcd3947ff8164d2e1428ca3461ef8a631ea7b6419673322fe2` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Protein sequence ESM-2 representations Folding module Predicted structure and confidence Individual claims	facebookresearch/esm: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T19:46:19.090082+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Protein sequence ESM-2 representations Folding module Predicted structure and confidence Individual claims	facebook/esmfold_v1: config.json Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 75a3841ee059df2bf4d56688166c8fb459ddd97a Retrieved: 2026-09-16T20:04:02.231029+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `6b98125e2685fef2875499f6bd7c83968a077993ab53f99bf5581113665f7cc6` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram steps Protein sequence ESM-2 representations Folding module Predicted structure and confidence Individual claims	facebook/esmfold_v1: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 75a3841ee059df2bf4d56688166c8fb459ddd97a Retrieved: 2026-09-16T20:04:02.231029+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.steps` Source artifact SHA-256: `12c535c3711211dcd3947ff8164d2e1428ca3461ef8a631ea7b6419673322fe2` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram title ESMFold workflow Individual claims	facebookresearch/esm: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T19:46:19.090082+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.title` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram title ESMFold workflow Individual claims	facebook/esmfold_v1: config.json Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 75a3841ee059df2bf4d56688166c8fb459ddd97a Retrieved: 2026-09-16T20:04:02.231029+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.title` Source artifact SHA-256: `6b98125e2685fef2875499f6bd7c83968a077993ab53f99bf5581113665f7cc6` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Diagram title ESMFold workflow Individual claims	facebook/esmfold_v1: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 75a3841ee059df2bf4d56688166c8fb459ddd97a Retrieved: 2026-09-16T20:04:02.231029+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.diagram.title` Source artifact SHA-256: `12c535c3711211dcd3947ff8164d2e1428ca3461ef8a631ea7b6419673322fe2` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact
Model type Sequence-to-structure protein prediction pipeline Individual claims	facebookresearch/esm: README.md Original source ↗ ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T19:46:19.090082+00:00	source checked automated source review · 2026-09-16 Audit details Inspected pinned official documentation, relevant implementation files and named primary-paper sections. Claims are limited to those artifacts. Remaining field extraction and identity conflicts are explicit; no new performance claims, model runs or human review are implied. Field: `attributes.profile.facts.0.value` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: SHA-256 of retrieved original artifact bytes Format: original_artifact Inspected artifact

How to read the evidence

Sources and history

Release 2026-10-12-fcce59cc481b · Record review: discovered

5 source records and release history

ESMFold official resource · Original source · Not reported
facebookresearch/esm: README.md · Original source · 2b369911bb5b4b0dda914521b9475cad1656b2ac
facebook/esmfold_v1: README.md · Original source · 75a3841ee059df2bf4d56688166c8fb459ddd97a
facebook/esmfold_v1: config.json · Original source · 75a3841ee059df2bf4d56688166c8fb459ddd97a
facebookresearch/esm: LICENSE · Original source · 2b369911bb5b4b0dda914521b9475cad1656b2ac

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Technical metadata and extraction receipts

Stable ID: catalog-model-esmfold

areas: proteins-complexes
method types: foundation_model
entity level: family
version: v1
reported name: ESMFold
access: Public checkpoint; materially larger than ESM-2 8M.
entity classification: review date: 2026-09-17; rationale: The cited profile describes a named learned biological predictor or representation model/family. Preserve this identity separately from task-specific fitting, individual checkpoints, pipelines and hosted access.; source ids: evidence-official-29d4b229a3aa426a6dfb; evidence-official-fa53ab621979fb5f37c8; evidence-official-867f2d1dcb4084248daa; source locator: ESM README: ESMFold Structure Prediction; official facebook/esmfold_v1 model card and config.json esmfold_config; ambiguities: None recorded

Related records

variant of: ESMFold
configuration of: ESMFold (ESMFold installed locally from its GitHub repository)
subject: ESMFold: description
subject: ESMFold: variant of ESMFold
family: ESMFold

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