rewirebio.iobenchmarks
Evaluation

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

Published fusion caller comparison; transcribed, not reproduced.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-09-ba02f2f4a36e · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 6 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: EricScript v0.5.5 (Tamura et al. 2026)Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
0.01 f1-score
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

rna-fusion-20261009-protocol-tamura2026-all-conventional

Aggregation: Not reported

Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript', column 'F1' (PDF page text)
Configuration: EricScript v0.5.5 (Tamura et al. 2026)Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
665 false-negative-count
count · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

rna-fusion-20261009-protocol-tamura2026-all-conventional

Aggregation: Not reported

Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript', column 'False negative' (PDF page text)
Configuration: EricScript v0.5.5 (Tamura et al. 2026)Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
160,271 false-positive-count
count · lower

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

rna-fusion-20261009-protocol-tamura2026-all-conventional

Aggregation: Not reported

Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript', column 'False positive' (PDF page text)
Configuration: EricScript v0.5.5 (Tamura et al. 2026)Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
0 precision
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

rna-fusion-20261009-protocol-tamura2026-all-conventional

Aggregation: Not reported

Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript', column 'Positive predictive value' (PDF page text)
Configuration: EricScript v0.5.5 (Tamura et al. 2026)Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
0.54 recall
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

rna-fusion-20261009-protocol-tamura2026-all-conventional

Aggregation: Not reported

Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript', column 'True positive rate' (PDF page text)
Configuration: EricScript v0.5.5 (Tamura et al. 2026)Protocol: All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset: CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
785 true-positive-count
count · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

EricScript on all fusions, conventional RNA-seq (Tamura et al. 2026)

rna-fusion-20261009-protocol-tamura2026-all-conventional

Aggregation: Not reported

Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies; Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12) · Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript', column 'True positive' (PDF page text)

Source checking is not independent reproduction. Release 2026-10-09-ba02f2f4a36e.

Evaluation procedure

rna-fusion-20261009-protocol-tamura2026-all-conventional

Configuration
EricScript v0.5.5 (Tamura et al. 2026)
Protocol
All fusions, conventional RNA-seq of haematologic cell lines, consensus truth (Tamura et al. 2026 Supplementary Table 3)
Dataset
CCLE haematologic malignancy cell lines, conventional RNA-seq (170 cell lines)
origin
Independent external evaluation
configuration
Primary source as retrieved 2026-10-09
protocol id
rna-fusion-20261009-protocol-tamura2026-all-conventional
dataset version
Not reported
split
All cell lines
population
170 cell lines
inputs
Conventional RNA-seq FASTQ, GRCh38
adaptation
Not reported
metric implementation
Gene pair and orientation match after HGNC alias resolution (Methods)
aggregation
Pooled over fusion-cell line pairs
budget
Not reported

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
All cell lines
Adaptation
Not reported
Scoring implementation
Gene pair and orientation match after HGNC alias resolution (Methods)

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

38 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-09-ba02f2f4a36e
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Not reported
Context-only references
Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NPJ Precision Oncology 10:199, published 2026-04-04; PMC13230599 full-text XML
Retrieved: 2026-10-09T20:37:17Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 540cf971970ad98557f3d4511f09c3f06a1b4359fe9276a25e29e731e36c0fc1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.adaptation
Not reported
Context-only references
Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12)

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41698_2026_1397_MOESM1_ESM.pdf as served by the publisher
Retrieved: 2026-10-09T20:37:37Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
Pooled over fusion-cell line pairs
Context-only references
Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NPJ Precision Oncology 10:199, published 2026-04-04; PMC13230599 full-text XML
Retrieved: 2026-10-09T20:37:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 540cf971970ad98557f3d4511f09c3f06a1b4359fe9276a25e29e731e36c0fc1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
Pooled over fusion-cell line pairs
Context-only references
Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12)

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41698_2026_1397_MOESM1_ESM.pdf as served by the publisher
Retrieved: 2026-10-09T20:37:37Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NPJ Precision Oncology 10:199, published 2026-04-04; PMC13230599 full-text XML
Retrieved: 2026-10-09T20:37:17Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 540cf971970ad98557f3d4511f09c3f06a1b4359fe9276a25e29e731e36c0fc1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12)

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41698_2026_1397_MOESM1_ESM.pdf as served by the publisher
Retrieved: 2026-10-09T20:37:37Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NPJ Precision Oncology 10:199, published 2026-04-04; PMC13230599 full-text XML
Retrieved: 2026-10-09T20:37:17Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 540cf971970ad98557f3d4511f09c3f06a1b4359fe9276a25e29e731e36c0fc1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12)

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41698_2026_1397_MOESM1_ESM.pdf as served by the publisher
Retrieved: 2026-10-09T20:37:37Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
Conventional RNA-seq FASTQ, GRCh38
Context-only references
Comparison of gene fusion detection algorithms reveals frequently overlooked driver fusions in hematologic malignancies

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: NPJ Precision Oncology 10:199, published 2026-04-04; PMC13230599 full-text XML
Retrieved: 2026-10-09T20:37:17Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 540cf971970ad98557f3d4511f09c3f06a1b4359fe9276a25e29e731e36c0fc1

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
Conventional RNA-seq FASTQ, GRCh38
Context-only references
Tamura et al. 2026, Supplementary Information (Supplementary Tables 1-12)

Original source ↗

Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: 41698_2026_1397_MOESM1_ESM.pdf as served by the publisher
Retrieved: 2026-10-09T20:37:37Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: f18ada098fd03b0842c63a8ab9d13002e1876b006243e42c640a118ea3ab3275

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-09-ba02f2f4a36e · Record review: source checked

2 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: rna-fusion-20261009-eval-tamura2026-ericscript-all-conventional

areas
rna-transcriptomes
contexts
clinical_research
origin
independent_paper
protocol
rna-fusion-20261009-protocol-tamura2026-all-conventional
version
Primary source as retrieved 2026-10-09
comparison
protocol id: rna-fusion-20261009-protocol-tamura2026-all-conventional; dataset version: Not reported; split: All cell lines; population: 170 cell lines; inputs: Conventional RNA-seq FASTQ, GRCh38; adaptation: Not reported; metric implementation: Gene pair and orientation match after HGNC alias resolution (Methods); aggregation: Pooled over fusion-cell line pairs; budget: Not reported
source locator
Supplementary Table 3, 'Conventional RNA-seq of cell lines', row 'EricScript'
missing metadata
comparison.dataset version: reason: unreported
denominator
1450
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