rewirebio.iobenchmarks
Evaluation

qwen-refined on foundationone (Lin et al. 2025)

Published comparison; transcribed, not reproduced.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-10-7b8f80935f90 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

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Verified: Not verified

Evidence incomplete

Investigate discrepancies

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Missing or unresolved evidence

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  • score semantics: verification is missing
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  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

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Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

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Verified: Not verified

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Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 1 result. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: Qwen 2.5 72B, refined prompt, temperature 0.8 (default) (Lin et al. 2025)Protocol: Lin et al. 2025 FoundationOne variants: clinically relevant vs VUS
Dataset: FoundationOne CDx report variants, 612 patients (Lin et al. 2025)
0.725 top-1-accuracy
fraction · higher

Uncertainty: Not reported by the source

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

qwen-refined on foundationone (Lin et al. 2025)

egfrnsclc-20261009-protocol-lin2025-foundationone-relevant-vs-vus

Aggregation: Not reported

Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification · Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Source checking is not independent reproduction. Release 2026-10-10-7b8f80935f90.

Evaluation procedure

egfrnsclc-20261009-protocol-lin2025-foundationone-relevant-vs-vus

Configuration
Qwen 2.5 72B, refined prompt, temperature 0.8 (default) (Lin et al. 2025)
Protocol
Lin et al. 2025 FoundationOne variants: clinically relevant vs VUS
Dataset
FoundationOne CDx report variants, 612 patients (Lin et al. 2025)
origin
Independent external evaluation
configuration
Primary source as retrieved 2026-10-09
protocol id
egfrnsclc-20261009-protocol-lin2025-foundationone-relevant-vs-vus
dataset version
egfrnsclc-20261009-data-lin2025-foundationone-variants
split
Whole table; no training split (prompted models)
population
clinically relevant vs VUS via CIViC levels
inputs
Gene, alteration and tumour type as a natural-language query
adaptation
Prompting only
metric implementation
Top-1 answer compared with the reference level
aggregation
Mean over 10 iterations
budget
Not reported

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Whole table; no training split (prompted models)
Adaptation
Prompting only
Scoring implementation
Top-1 answer compared with the reference level

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

18 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-10-7b8f80935f90
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Prompting only
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
Mean over 10 iterations
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
egfrnsclc-20261009-data-lin2025-foundationone-variants
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
Gene, alteration and tumour type as a natural-language query
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Top-1 answer compared with the reference level
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.population
clinically relevant vs VUS via CIViC levels
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
egfrnsclc-20261009-protocol-lin2025-foundationone-relevant-vs-vus
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.split
Whole table; no training split (prompted models)
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
independent_paper
Context-only references
Benchmarking large language models GPT-4o, llama 3.1, and qwen 2.5 for cancer genetic variant classification

Original source ↗

Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'

Version: npj Precision Oncology 9:141, published 2025-05-15; PMC12078457 full-text XML
Retrieved: 2026-10-09T20:43:36Z

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.origin

Source artifact SHA-256: 09c67fcaf7b367d74500db5fd015968389371dcb9ee5a37ccc83241aa63c0f80

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-10-7b8f80935f90 · Record review: source checked

1 source records and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: egfrnsclc-20261009-eval-lin2025-qwen-refined-foundationone

areas
dna-genomes
contexts
clinical_research
origin
independent_paper
protocol
egfrnsclc-20261009-protocol-lin2025-foundationone-relevant-vs-vus
version
Primary source as retrieved 2026-10-09
comparison
protocol id: egfrnsclc-20261009-protocol-lin2025-foundationone-relevant-vs-vus; dataset version: egfrnsclc-20261009-data-lin2025-foundationone-variants; split: Whole table; no training split (prompted models); population: clinically relevant vs VUS via CIViC levels; inputs: Gene, alteration and tumour type as a natural-language query; adaptation: Prompting only; metric implementation: Top-1 answer compared with the reference level; aggregation: Mean over 10 iterations; budget: Not reported
source locator
Table 2 (Tab2), row 2 ('Qwen2.5', 'Refined prompt + Default temperature (0.8)', 'FoundationOne'), column 'Accuracy'
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