rewirebio.iobenchmarks
Evaluation

STAR-Fusion evaluation

STAR-Fusion evaluation; bounded primary-source AMP candidate.

Research readiness

These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-10-07-1448159e6a81 · Evidence verified: Not verified

Evidence incomplete

Replay metrics

Exact outcomes, predictions, identifiers and evaluator are connected.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing

Verified: Not verified

Evidence incomplete

Investigate discrepancies

Replay evidence includes annotations and an assessment of dependence. Unknown independence permits descriptive analysis only.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • recipe pinned: verification is missing
  • resource estimate: verification is missing

Verified: Not verified

Evidence incomplete

Validate independently

Separate data and exposure records support an independent test.

Missing or unresolved evidence

  • No verified artifact manifest is linked to this exact record.
  • artifact hashes: verification is missing
  • join integrity: verification is missing
  • score semantics: verification is missing
  • independent validation: verification is missing
  • overlap checked: verification is missing

Verified: Not verified

Readiness describes the evidence in this release. Availability on your computer is checked separately when an investigation runs. Existing data exposure can prevent independent validation even when files are available.

Artifacts and reproduction

No verified artifact manifest is connected to this record yet. The gaps above identify what is needed before analysis can begin.

Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 4 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: STAR-FusionProtocol: EnFusion undiluted Seraseq duplicate benchmark
Dataset: Undiluted Seraseq Fusion RNA control, duplicate libraries
14 mean Seraseq fusions identified
fusions · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

STAR-Fusion evaluation

Consensus ≥3 callers, with specified filtering and known fusion list rescue; Table 2 displays mean of duplicate undiluted experiments. Only 14 Seraseq fusions are positive; all others counted false positive. Comparators processed by same authors.

Aggregation: Not reported

Discovery of clinically relevant fusions in pediatric cancer · Table 2, STAR-Fusion row, corresponding column (JATS Tab2)
Configuration: STAR-FusionProtocol: EnFusion undiluted Seraseq duplicate benchmark
Dataset: Undiluted Seraseq Fusion RNA control, duplicate libraries
32 mean total fusions identified
fusions · lower

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

STAR-Fusion evaluation

Consensus ≥3 callers, with specified filtering and known fusion list rescue; Table 2 displays mean of duplicate undiluted experiments. Only 14 Seraseq fusions are positive; all others counted false positive. Comparators processed by same authors.

Aggregation: Not reported

Discovery of clinically relevant fusions in pediatric cancer · Table 2, STAR-Fusion row, corresponding column (JATS Tab2)
Configuration: STAR-FusionProtocol: EnFusion undiluted Seraseq duplicate benchmark
Dataset: Undiluted Seraseq Fusion RNA control, duplicate libraries
43.6% precision
% · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

STAR-Fusion evaluation

Consensus ≥3 callers, with specified filtering and known fusion list rescue; Table 2 displays mean of duplicate undiluted experiments. Only 14 Seraseq fusions are positive; all others counted false positive. Comparators processed by same authors.

Aggregation: Not reported

Discovery of clinically relevant fusions in pediatric cancer · Table 2, STAR-Fusion row, corresponding column (JATS Tab2)
Configuration: STAR-FusionProtocol: EnFusion undiluted Seraseq duplicate benchmark
Dataset: Undiluted Seraseq Fusion RNA control, duplicate libraries
100% sensitivity
% · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Independent external evaluation · Source checked
Methods, coverage and source

STAR-Fusion evaluation

Consensus ≥3 callers, with specified filtering and known fusion list rescue; Table 2 displays mean of duplicate undiluted experiments. Only 14 Seraseq fusions are positive; all others counted false positive. Comparators processed by same authors.

Aggregation: Not reported

Discovery of clinically relevant fusions in pediatric cancer · Table 2, STAR-Fusion row, corresponding column (JATS Tab2)

Source checking is not independent reproduction. Release 2026-10-07-1448159e6a81.

Evaluation procedure

Consensus ≥3 callers, with specified filtering and known fusion list rescue; Table 2 displays mean of duplicate undiluted experiments. Only 14 Seraseq fusions are positive; all others counted false positive. Comparators processed by same authors.

Configuration
STAR-Fusion
Protocol
EnFusion undiluted Seraseq duplicate benchmark
Dataset
Undiluted Seraseq Fusion RNA control, duplicate libraries
origin
Independent external evaluation
configuration
Not reported
adaptation
Not reported
aggregation
duplicate experiment averages
budget
Not reported
dataset version
Not reported
inputs
paired-end RNA-seq reads
metric implementation
Not reported
population
14 synthetic fusions; duplicate experiments
protocol id
Not reported
split
optimization/reference control

Metadata review: source checked. Unreported conditions prevent automatic comparisons.

Reproduction

Split
optimization/reference control
Adaptation
Not reported
Scoring implementation
Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

17 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-07-1448159e6a81
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
Not reported
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.aggregation
duplicate experiment averages
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.inputs
paired-end RNA-seq reads
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.inputs

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.metric_implementation
Not reported
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.metric_implementation

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.population
14 synthetic fusions; duplicate experiments
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.population

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.protocol_id
Not reported
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

missing or unspecified

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.protocol_id

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.comparison.split
optimization/reference control
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.comparison.split

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

attributes.origin
independent_paper
Context-only references
Discovery of clinically relevant fusions in pediatric cancer

Original source ↗

No field-specific location recorded

Version: Europe PMC fullTextXML retrieved 2026-10-07T12:25:20.810843+00:00
Retrieved: 2026-10-07T12:25:20.810843+00:00

not individually reviewed

No individual claim review recorded

independent paper

Audit details

Field: attributes.origin

Source artifact SHA-256: a5fd574d3b186fa29f835aff44491e1d1d0447ea2352f627c21f95ca666e9225

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-10-07-1448159e6a81 · Record review: source checked

1 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: amp-oncology-rna-20261007-issue-11-eval-star-fusion

comparison
adaptation: Not reported; aggregation: duplicate experiment averages; budget: Not reported; dataset version: Not reported; inputs: paired-end RNA-seq reads; metric implementation: Not reported; population: 14 synthetic fusions; duplicate experiments; protocol id: Not reported; split: optimization/reference control
missing metadata
budget: Unknown; dataset version: Table 2 caption says v3; Fig1 and Par31/50 discuss undiluted v2. Do not resolve silently.; metric implementation: Printed percentage retained; per-replicate aggregation details not extracted; pipeline version: EnFusion software release/commit not established
origin
independent_paper
protocol
Consensus ≥3 callers, with specified filtering and known fusion list rescue; Table 2 displays mean of duplicate undiluted experiments. Only 14 Seraseq fusions are positive; all others counted false positive. Comparators processed by same authors.
version
Not reported
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