rewire.itbenchmarks
Evaluation

AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks

Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.

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These checks assess whether the evidence supports a reproducible investigation. A source-checked score alone does not meet these requirements.

Release 2026-09-29-06401fd5b220 · Evidence verified: Not verified

Evidence incomplete

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Verified: Not verified

Evidence incomplete

Investigate discrepancies

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Missing or unresolved evidence

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  • artifact hashes: verification is missing
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  • metric replay: verification is missing
  • annotations: verification is missing
  • dependence: verification is missing

Verified: Not verified

Evidence incomplete

Run locally

A pinned recipe describes the inputs, environment and resource requirements.

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Verified: Not verified

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Validate independently

Separate data and exposure records support an independent test.

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Verified: Not verified

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Read reviewed discrepancy investigations

Evaluation results

1 evaluation · 3 results. Different protocols are not a single leaderboard.

Filter evaluations

Applied filters: All linked evaluations

Exact evaluated configurations and original reported results
Tested configurationProtocol and datasetFindingEvidence and details
Configuration: AlphaGenome fold-0 track model on comparator-matched test peaksProtocol: ATAC prediction on held-out peaks (AlphaGenome paper)
Dataset subset: ATAC prediction on held-out peaks: evaluated data subset
0.86 pearsonr
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks

Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.

Aggregation: Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.

AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K28
Configuration: AlphaGenome fold-0 track model on comparator-matched test peaksProtocol: ATAC prediction on held-out peaks (AlphaGenome paper)
Dataset subset: ATAC prediction on held-out peaks: evaluated data subset
0.85 log1p_count_pearsonr
correlation · higher

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks

Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.

Aggregation: Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.

AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K29
Configuration: AlphaGenome fold-0 track model on comparator-matched test peaksProtocol: ATAC prediction on held-out peaks (AlphaGenome paper)
Dataset subset: ATAC prediction on held-out peaks: evaluated data subset
0.46 profile jsd
dimensionless · lower

Uncertainty: Not reported

Coverage: Not reported scored / Not reported eligible

Author-reported evaluation · Source checked
Methods, coverage and source

AlphaGenome fold-0 track model on comparator-matched test peaks: ATAC prediction on held-out peaks

Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.

Aggregation: Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.

AlphaGenome Nature 2026 supplementary comparison tables · 'Suppl Table 3 Track performance'!K30

Source checking is not independent reproduction. Release 2026-09-29-06401fd5b220.

Evaluation procedure

Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.

Configuration
AlphaGenome fold-0 track model on comparator-matched test peaks
Protocol
ATAC prediction on held-out peaks (AlphaGenome paper)
Dataset subset
ATAC prediction on held-out peaks: evaluated data subset
origin
Author-reported evaluation
configuration
AlphaGenome fold-0 track model on comparator-matched test peaks
protocol id
alphagenome-2026-t3-protocol-16
dataset version
Not reported
split
Intersect ChromBPNet fold-0 test peaks with regions that do not overlap AlphaGenome fold-0 training intervals.
population
ChromBPNet test peak regions, fold 0. Only directly matching ENCODE experiment accessions are used.
inputs
Not reported
adaptation
AlphaGenome fold-0 track model on comparator-matched test peaks
metric implementation
Not reported
aggregation
Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.
budget
Not reported

Metadata review: needs review. Unreported conditions prevent automatic comparisons.

Reproduction

Split
Intersect ChromBPNet fold-0 test peaks with regions that do not overlap AlphaGenome fold-0 training intervals.
Adaptation
AlphaGenome fold-0 track model on comparator-matched test peaks
Scoring implementation
Not reported

No execution recipe has been verified for this exact configuration and evaluation. A benchmark's general instructions may use different inputs, splits or model settings.

Reproducing this published result requires matching its model configuration, data, split and scorer. Source checking or a successful smoke test does not establish score reproduction.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

63 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-09-29-06401fd5b220
Property and statementOriginal source and locationReview and provenance
attributes.comparison.adaptation
AlphaGenome fold-0 track model on comparator-matched test peaks
Context-only references
alphagenome: Journal full-text XML

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

attributes.comparison.adaptation
AlphaGenome fold-0 track model on comparator-matched test peaks
Context-only references
AlphaGenome Nature 2026 supplementary methods

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

attributes.comparison.adaptation
AlphaGenome fold-0 track model on comparator-matched test peaks
Context-only references
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.adaptation

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

attributes.comparison.aggregation
Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.
Context-only references
alphagenome: Journal full-text XML

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

attributes.comparison.aggregation
Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.
Context-only references
AlphaGenome Nature 2026 supplementary methods

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

attributes.comparison.aggregation
Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.
Context-only references
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

not individually reviewed

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.aggregation

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
alphagenome: Journal full-text XML

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
AlphaGenome Nature 2026 supplementary methods

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Supplement to Nature version of record, 28 January 2026; content hash pinned
Retrieved: 2026-09-17T06:37:01.778972+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 86b2e6a07543e3c201e2e157a3e9c6eb5235ff13eb8a5224f6fcb6fe1808d4c0

Hash scope: SHA-256 of exact publisher PDF bytes

Format: original_pdf

Inspected artifact

attributes.comparison.budget
Not reported
Context-only references
AlphaGenome Nature 2026 supplementary comparison tables

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Nature version of record, 28 January 2026
Retrieved: 2026-09-17T06:31:06.887921+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.budget

Source artifact SHA-256: 833cb78b6ae6fe39415cfff296ac00c48d800326139f13eb307531a1cc133154

Hash scope: SHA-256 of exact retrieved original artifact bytes

Format: xlsx

Inspected artifact

attributes.comparison.dataset_version
Not reported
Context-only references
alphagenome: Journal full-text XML

Original source ↗

No field-specific location recorded

Shared locator for this statement’s cited sources; not a separate locator for each citation.

Version: Retrieved page snapshot; no immutable publisher revision supplied
Retrieved: 2026-09-16T19:53:03.009088+00:00

missing or unspecified

No individual claim review recorded

author reported

Audit details

Field: attributes.comparison.dataset_version

Source artifact SHA-256: d159b791fc6cb7b679c151727b7b05a6e5b6388b08a89b675014983d85b6df36

Hash scope: SHA-256 of retrieved original artifact bytes

Format: original_artifact

Inspected artifact

Sources and history

View linked audit checks and correction history

Release 2026-09-29-06401fd5b220 · Record review: needs review

3 source records and release historyDownload this release
Technical metadata and extraction receipts

Stable ID: alphagenome-2026-evaluation-9a1d232336798866

areas
dna-genomes
origin
author_reported
protocol
Evaluate signal correlation, log-total-count correlation and profile JSD as separate metrics; retain only endpoints actually listed for this evaluation in Table3.
version
AlphaGenome fold-0 track model on comparator-matched test peaks
source evaluation index
16
source table
3
comparison
protocol id: alphagenome-2026-t3-protocol-16; dataset version: Not reported; split: Intersect ChromBPNet fold-0 test peaks with regions that do not overlap AlphaGenome fold-0 training intervals.; population: ChromBPNet test peak regions, fold 0. Only directly matching ENCODE experiment accessions are used.; inputs: Not reported; adaptation: AlphaGenome fold-0 track model on comparator-matched test peaks; metric implementation: Not reported; aggregation: Table3 reports task summary scalars; Extended Data Fig.3 shows per-cell-line comparisons. The inspected caption does not fully specify pooling across peaks/cell lines.; budget: Not reported
context
allowed inputs: Reference DNA; predicted and observed base-resolution profiles on matched assay peaks.; limitations: JSD is lower-is-better. The article calls it both Jensen–Shannon distance and divergence; the precise implementation is not resolved by these descriptions. Matching held-out intervals does not establish external pretraining decontamination.
missing metadata
dataset version: unextracted; exact input manifest: unextracted; inference budget: unreported; scoring failures: unreported
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