GPT-OSS-120B (AssayBench)
Configuration of GPT-OSS-120B: zero-shot.
Overview
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Evaluations and results
3 evaluations · 9 results. Different protocols are not a single leaderboard.
Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen
Sorted by Adjusted NDCG at 100 (post-cutoff cohort; mean over benchmark entries) (higher is better). The best value in each column is highlighted. Decimals are rounded for display; each value links to the printed value and its source.
| Tested configuration | Protocol and dataset | Adjusted NDCG at 100 (post-cutoff cohort; mean over benchmark entries) | Adjusted NDCG at 100 (test cohort; mean over benchmark entries) | Adjusted NDCG at 100 (validation cohort; mean over benchmark entries) | Directional false discovery rate at 100 (post-cutoff cohort; mean over benchmark entries) | Directional false discovery rate at 100 (test cohort; mean over benchmark entries) | Directional false discovery rate at 100 (validation cohort; mean over benchmark entries) | Precision at 100 (post-cutoff cohort; mean over benchmark entries; denominator min(100, positive-relevance genes)) | Precision at 100 (test cohort; mean over benchmark entries; denominator min(100, positive-relevance genes)) | Precision at 100 (validation cohort; mean over benchmark entries; denominator min(100, positive-relevance genes)) |
|---|---|---|---|---|---|---|---|---|---|---|
| GPT-OSS-120B (AssayBench)Evaluation | AssayBench post-cutoff cohort of human CRISPR screens | 0.0826 | Not reported | Not reported | NA | Not reported | Not reported | 0.25 | Not reported | Not reported |
| GPT-OSS-120B (AssayBench)Evaluation | AssayBench test cohort of human CRISPR screens | Not reported | 0.121 | Not reported | Not reported | 0.0223 | Not reported | Not reported | 0.176 | Not reported |
| GPT-OSS-120B (AssayBench)Evaluation | AssayBench validation cohort of human CRISPR screens | Not reported | Not reported | 0.127 | Not reported | Not reported | 0.0164 | Not reported | Not reported | 0.229 |
All 9 result rows with coverage, uncertainty and sources
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| Tested configuration | Protocol and dataset | Finding | Evidence and details |
|---|---|---|---|
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench post-cutoff cohort of human CRISPR screens | 0.0826 Adjusted NDCG at 100 (post-cutoff cohort; mean over benchmark entries) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench post-cutoff cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'LaTest', column 'AnDCG@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench post-cutoff cohort of human CRISPR screens | NA Directional false discovery rate at 100 (post-cutoff cohort; mean over benchmark entries) fraction · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench post-cutoff cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'LaTest', column 'dFDR@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench post-cutoff cohort of human CRISPR screens | 0.25 Precision at 100 (post-cutoff cohort; mean over benchmark entries; denominator min(100, positive-relevance genes)) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench post-cutoff cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'LaTest', column 'Precision@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench test cohort of human CRISPR screens | 0.121 Adjusted NDCG at 100 (test cohort; mean over benchmark entries) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench test cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'test', column 'AnDCG@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench test cohort of human CRISPR screens | 0.0223 Directional false discovery rate at 100 (test cohort; mean over benchmark entries) fraction · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench test cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'test', column 'dFDR@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench test cohort of human CRISPR screens | 0.176 Precision at 100 (test cohort; mean over benchmark entries; denominator min(100, positive-relevance genes)) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench test cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'test', column 'Precision@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench validation cohort of human CRISPR screens | 0.127 Adjusted NDCG at 100 (validation cohort; mean over benchmark entries) unitless · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench validation cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'val', column 'AnDCG@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench validation cohort of human CRISPR screens | 0.0164 Directional false discovery rate at 100 (validation cohort; mean over benchmark entries) fraction · lower Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench validation cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'val', column 'dFDR@100' |
| Configuration: GPT-OSS-120B (AssayBench) | Protocol: AssayBench: rank 100 candidate genes for a described CRISPR screen Dataset: AssayBench validation cohort of human CRISPR screens | 0.229 Precision at 100 (validation cohort; mean over benchmark entries; denominator min(100, positive-relevance genes)) fraction · higher Uncertainty: Not reported by the source Coverage: Not reported scored / Not reported eligible | Independent external evaluation · Source checkedMethods, coverage and sourceGPT-OSS-120B on the AssayBench validation cohort tgtval-20261009-protocol-debrouwer2026-screen-gene-ranking Aggregation: Not reported AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Table 3, row 'GPT-OSS-120B' cohort 'val', column 'Precision@100' |
Source checking is not independent reproduction. Release 2026-11-02-a7f03c9e55a5.
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Sources and history
Release 2026-11-02-a7f03c9e55a5 · Record review: source checked
1 source record and release history
- AssayBench: An Assay-Level Virtual Cell Benchmark for LLMs and Agents · Original source · arXiv:2605.10876 version 1, posted 2026-05-11; not peer reviewed
Technical metadata and extraction receipts
Stable ID: tgtval-20261009-config-debrouwer2026-gpt-oss-120b
- areas
- cells-tissues
- contexts
- research
- method types
- foundation_model
- reported name
- GPT-OSS-120B
- foundation model eligible
- true
- source locator
- Tables 2-3 row labels; section 4
- missing metadata
- version: reason: unreported; note: No release or commit is printed for this configuration
- parameters
- zero-shot
- provenance note
- Configuration as run in the cited comparison.
Related records
- configuration of: GPT-OSS-120B
- system: GPT-OSS-120B on the AssayBench post-cutoff cohort
- system: GPT-OSS-120B on the AssayBench test cohort
- system: GPT-OSS-120B on the AssayBench validation cohort