rewirebio.iobenchmarks
Evidence claim

gfm-guide-20261014-eval-hegde-nt-500m-human-ref-convergence: attributes.comparison.adaptation

Comparison: adaptation of NT 500M human reference, fine-tuning time to convergence (Hegde et al. 2025)

LoRA parameter-efficient fine-tuning (peft; r=1, lora_alpha=32, lora_dropout=0.1)

The evaluation said full fine-tuning. Hegde et al. 2025 list LoRA parameter-efficient fine-tuning through peft for this model; the configuration record of the 5-epoch run already says so. Historical releases retain the previous value.

Evidence

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Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

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7 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statementOriginal source and locationReview and provenance
Claimed field
attributes.comparison.adaptation
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Previous value
Full fine-tuning
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed value
LoRA parameter-efficient fine-tuning (peft; r=1, lora_alpha=32, lora_dropout=0.1)
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
The evaluation said full fine-tuning. Hegde et al. 2025 list LoRA parameter-efficient fine-tuning through peft for this model; the configuration record of the 5-epoch run already says so. Historical releases retain the previous value.
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Relationship: subject
gfm-guide-20261014-eval-hegde-nt-500m-human-ref-convergence
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: links:subject:gfm-guide-20261014-eval-hegde-nt-500m-human-ref-convergence

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
gfm-guide-20261014-eval-hegde-nt-500m-human-ref-convergence: attributes.comparison.adaptation
Context-only references
Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction

Original source ↗

gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')

Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML
Retrieved: 2026-10-14T12:48:26Z

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 9ea68b688637b40f0aeced7c905822f6b14c352a3a935c61c407945f3d66ef47

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: metadata-correction-gfm-guide-20261014-hegde-nt-500m-human-ref-convergence-adaptation

field
attributes.comparison.adaptation
previous value
Full fine-tuning
value
LoRA parameter-efficient fine-tuning (peft; r=1, lora_alpha=32, lora_dropout=0.1)
source locator
gfm-guide-20261014-source-hegde2025: Appendix A.3 ('Parameter-efficient fine-tuning using the peft package: r = 1; lora_alpha = 32; lora_dropout = 0.1')
review
method: source-hash-verification; scope-review; reviewer: claude; reviewer note: Claude (Opus 5.5) review agent review-169, independent of the agent that drafted these judgements for issue #162; no human review claimed; date: 2026-10-14; note: Applied by the independent reviewer of PR #169. See docs/reviews/use-cases/diagnostic-genomics-model-execution-judgements-2026-10-14.md.
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