use-case-diagnostic-genomics-model-execution: attributes.decision
Decision of Select an execution workflow for large-scale diagnostic genomics
Compare published per-sample runtime and cost of CPU, GPU and DRAGEN server execution set-ups that resemble the team's hardware and sequencing type when budgeting a workflow; most are conventional variant-calling pipelines, the two active foundation-model benchmarks (inference on microbial genomes; fine-tuning and test-set scoring on human eQTL variants) are outside any diagnostic workflow, and none measures run-to-run concordance of variant calls.
Updated for the Hegde et al. 2025 judgements that became active in PR #169, which make a second linked foundation-model study, and for the newly linked withheld and outside-scope studies. Historical releases retain the previous value.
Evidence
Source checking verifies the cited claim or transcription. It does not establish independent reproduction.
Evidence table
Inspect claims, sources and review details
Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.
One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.
7 evidence rows matching the loaded filters
| Property and statement | Original source and location | Review and provenance |
|---|---|---|
| Claimed field attributes.decision Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Previous value Compare published per-sample runtime and cost of CPU, GPU and DRAGEN server execution set-ups that resemble the team's hardware and sequencing type when budgeting a workflow; most are conventional variant-calling pipelines, the one active foundation-model inference benchmark is outside any diagnostic workflow, and none measures run-to-run concordance of variant calls. Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Source location Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Claimed value Compare published per-sample runtime and cost of CPU, GPU and DRAGEN server execution set-ups that resemble the team's hardware and sequencing type when budgeting a workflow; most are conventional variant-calling pipelines, the two active foundation-model benchmarks (inference on microbial genomes; fine-tuning and test-set scoring on human eQTL variants) are outside any diagnostic workflow, and none measures run-to-run concordance of variant calls. Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Description Updated for the Hegde et al. 2025 judgements that became active in PR #169, which make a second linked foundation-model study, and for the newly linked withheld and outside-scope studies. Historical releases retain the previous value. Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Relationship: subject use-case-diagnostic-genomics-model-execution Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
| Name use-case-diagnostic-genomics-model-execution: attributes.decision Context-only references | Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope Version: Genes 16(11):1358, 2025; PMC12652071 full-text XML | not individually reviewed No individual claim review recorded Audit detailsField: Source artifact SHA-256: Hash scope: Hash scope not separately documented; inspect source record |
Sources and history
Release 2026-10-22-1b7cf027e4f6 · Record review: source checked
1 source record and release history
- Reaping the Fruits of LLM Pruning: Towards Small Language Models for Efficient Non-Coding Variant Effect Prediction · Original source · Genes 16(11):1358, 2025; PMC12652071 full-text XML
Technical metadata and extraction receipts
Stable ID: metadata-correction-gfm-guide-20261014-execution-decision
- field
- attributes.decision
- previous value
- Compare published per-sample runtime and cost of CPU, GPU and DRAGEN server execution set-ups that resemble the team's hardware and sequencing type when budgeting a workflow; most are conventional variant-calling pipelines, the one active foundation-model inference benchmark is outside any diagnostic workflow, and none measures run-to-run concordance of variant calls.
- value
- Compare published per-sample runtime and cost of CPU, GPU and DRAGEN server execution set-ups that resemble the team's hardware and sequencing type when budgeting a workflow; most are conventional variant-calling pipelines, the two active foundation-model benchmarks (inference on microbial genomes; fine-tuning and test-set scoring on human eQTL variants) are outside any diagnostic workflow, and none measures run-to-run concordance of variant calls.
- source locator
- Store: reviewed judgements use-case-mapping-gfm-guide-20261014-hegde2025-eqtl-5-epochs and -eqtl-convergence become active; the EVEE and Nucleotide Transformer IA3 judgements are reviewed and withheld; the NTv3 and HyenaDNA judgements are outside scope
- review
- method: source-hash-verification; scope-review; reviewer: claude; reviewer note: Claude (Opus 5.5) review agent review-169, independent of the agent that drafted these judgements for issue #162; no human review claimed; date: 2026-10-14; note: Applied by the independent reviewer of PR #169. See docs/reviews/use-cases/diagnostic-genomics-model-execution-judgements-2026-10-14.md.