rewirebio.iobenchmarks
Evidence claim

MegSite + ESM3: description

Description of MegSite + ESM3

Predicts nucleic-acid-binding residues by fusing multimodal ESM3 sequence, structure and function embeddings with ESM-MSA features through cross-attention, alongside an equivariant graph network over the residue contact map.

Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.

Evidence

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Evidence table

Inspect claims, sources and review details

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7 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statementOriginal source and locationReview and provenance
Claimed field
description
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.field

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Previous value
Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers.
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.previous_value

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Source location
Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.source_locator

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Claimed value
Predicts nucleic-acid-binding residues by fusing multimodal ESM3 sequence, structure and function embeddings with ESM-MSA features through cross-attention, alongside an equivariant graph network over the residue contact map.
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: attributes.value

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Description
Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: description

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Relationship: subject
reported-model-86393c76dd8fa9
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: links:subject:reported-model-86393c76dd8fa9

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Name
MegSite + ESM3: description
Context-only references
MegSite: an accurate nucleic acid-binding residue prediction method based on multimodal protein language model

Original source ↗

Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)

Version: journal full text in PMC
Retrieved: 2026-09-16T10:38:57.558213+00:00

not individually reviewed

No individual claim review recorded

Audit details

Field: name

Source artifact SHA-256: 10d13122331813243d83b84fe6f9294eac7e7c03cde082ebed276191ac41089c

Hash scope: Hash scope not separately documented; inspect source record

Inspected artifact

Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

1 source record and release historyDownload this release (gzip)
Technical metadata and extraction receipts

Stable ID: metadata-correction-e36088ab7ca7e93c9955

areas
proteins-complexes
field
description
previous value
Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers.
value
Predicts nucleic-acid-binding residues by fusing multimodal ESM3 sequence, structure and function embeddings with ESM-MSA features through cross-attention, alongside an equivariant graph network over the residue contact map.
source locator
Reviewed profile (2026-09-16): summary at Bidirectional cross-attention fusion/The architecture of MegSite (paragraph 1); Bidirectional cross-attention fusion/Implementation details (paragraph 2); architecture fact at Results/Performance of different network architectures (paragraph 7); Materials and methods/Multimodal protein language model (paragraph 2); description text also read at Abstract; Results (MegSite architecture overview)
review
method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked all 11 scTab and MPRabc method descriptions against PMC11298532 and PMC13232518, and Lazypipe-nt, scaLR, CATHe2, DiffDock-NMDN, PC-mer and Hi-Enhancer against their papers; all match. The other pipeline descriptions are consistent with their pinned papers.; receipt: data/omics/qa-descriptions-20261011-c/review.json
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