Evidence claim

CLAPE-SMB with ESM-2: description

Predicts small-molecule-binding residues from sequence alone, using frozen esm2_t33_650M_UR50D residue embeddings with a contrastive-learning binding-site predictor.

Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value.

Evidence

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Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

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14 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-11-02-a7f03c9e55a5
Property and statement	Original source and location	Review and provenance
Claimed field description Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Claimed field description Context-only references	facebookresearch/esm README.md Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T20:00:00.816433+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.field` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Previous value Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers. Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Previous value Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers. Context-only references	facebookresearch/esm README.md Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T20:00:00.816433+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.previous_value` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Source location Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Source location Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Context-only references	facebookresearch/esm README.md Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T20:00:00.816433+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.source_locator` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Claimed value Predicts small-molecule-binding residues from sequence alone, using frozen esm2_t33_650M_UR50D residue embeddings with a contrastive-learning binding-site predictor. Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded Audit details Field: `attributes.value` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Claimed value Predicts small-molecule-binding residues from sequence alone, using frozen esm2_t33_650M_UR50D residue embeddings with a contrastive-learning binding-site predictor. Context-only references	facebookresearch/esm README.md Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T20:00:00.816433+00:00	not individually reviewed No individual claim review recorded Audit details Field: `attributes.value` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Description Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value. Context-only references	Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: version of record Retrieved: 2026-09-16T10:41:06Z	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `215919244c3dd2dfb0b55fce91c211430fd8d4aee4bb28bd03eab9f4feb73e62` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact
Description Replace a placeholder description with a sourced functional description (issue #88). Historical releases retain the original value. Context-only references	facebookresearch/esm README.md Original source ↗ Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract Shared locator for this statement’s cited sources; not a separate locator for each citation. Version: 2b369911bb5b4b0dda914521b9475cad1656b2ac Retrieved: 2026-09-16T20:00:00.816433+00:00	not individually reviewed No individual claim review recorded Audit details Field: `description` Source artifact SHA-256: `8b273c21a322fc9473d1b68d0dd40c8166ab2f89e4a190aa26ca87251b97cba9` Hash scope: Hash scope not separately documented; inspect source record Inspected artifact

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Sources and history

Release 2026-11-02-a7f03c9e55a5 · Record review: source checked

2 source records and release history

Protein-small molecule binding site prediction based on a pre-trained protein language model with contrastive learning · Original source · version of record
facebookresearch/esm README.md · Original source · 2b369911bb5b4b0dda914521b9475cad1656b2ac

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Technical metadata and extraction receipts

Stable ID: metadata-correction-bf48adc78ad5d9baffac

areas: proteins-complexes
field: description
previous value: Identity as reported in this paper. Unspecified versions are not assumed equivalent to other papers.
value: Predicts small-molecule-binding residues from sequence alone, using frozen esm2_t33_650M_UR50D residue embeddings with a contrastive-learning binding-site predictor.
source locator: Reviewed profile (2026-09-16): summary at Conclusion (paragraph 1); Results/Comparison of CLAPE-SMB with DeepProSite and heuristic analyses in three protein case studies (paragraph 3); architecture fact at Methods/Sequence embedding (paragraph 2); Methods/Loss function (paragraph 5); description text also read at Abstract
review: method: automated-source-review; ai-assisted-source-review; reviewer: claude; reviewer note: Extractor: Claude integrator agent for issue #88. Reviewer: a separate Claude review agent, independent of the extractor; no human review claimed.; date: 2026-10-11; method note: Compared the store diff with origin/main, read each new description against its cited source passage and checked the licence of each new source record.; note: Approved. Checked all 11 scTab and MPRabc method descriptions against PMC11298532 and PMC13232518, and Lazypipe-nt, scaLR, CATHe2, DiffDock-NMDN, PC-mer and Hi-Enhancer against their papers; all match. The other pipeline descriptions are consistent with their pinned papers.; receipt: data/omics/qa-descriptions-20261011-c/review.json

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subject: CLAPE-SMB with ESM-2

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