Evidence claim

LIT-PCBA dataset subsets: used_in retargeted from a dataset to the protocol

Evidence concern: excluded from comparisons

The official page (data content table, artifact a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e) gives 7761 actives and 382674 unique inactives for the 15 LIT-PCBA target sets, while Shen et al. 2025 (Methods 'Datasets', artifact 11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8) state 10030 confirmed actives and 2798737 confirmed inactives for the full set. The two counts are not reconciled by either source; the difference is most likely unique against per-target inactives, but neither source says so. EF and NEF both depend on this ratio, so the conflict is left unresolved and marked rather than reconciled.LIT-PCBA official project page, drugdesign.unistra.fr · Official page data content table (artifact a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e) against Shen et al. 2025 Methods 'Datasets' (artifact 11a4cee97057d9e72f9393024d22fdd169e3134f493367eee2f7869facf9ccf8)

Links of LIT-PCBA five-target screening (Shen et al. 2025 Table 4)

hitdisc-20261022-subset-litpcba-esr-ago: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-esr-antago: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-mapk1: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-pparg: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-tp53: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}]

The five subset records linked used_in to the five-target dataset. shared/omics/relations.ts defines used_in as data to an assessment ('Dataset subset to the protocol that uses it'), so a dataset is not a legal target and the store refused the batch. The links now point at the five-target LIT-PCBA protocol. The parent dataset is already recorded in each subset's attributes.source_dataset.

Evidence

Source checking verifies the cited claim or transcription. It does not establish independent reproduction.

Evidence table

Inspect claims, sources and review details

Trace each statement to its source and review. A context-only reference supports the record generally; it does not verify an individual field. Source checking does not reproduce an experiment.

One row per statement and cited source. Multiple citations are not independent evaluations. Shared locators are labelled explicitly.

7 evidence rows matching the loaded filters

Claims, original sources and review scope · Release 2026-10-22-1b7cf027e4f6
Property and statement	Original source and location	Review and provenance
Claimed field links Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.field` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.
Previous value hitdisc-20261022-subset-litpcba-esr-ago: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] \| hitdisc-20261022-subset-litpcba-esr-antago: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] \| hitdisc-20261022-subset-litpcba-mapk1: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] \| hitdisc-20261022-subset-litpcba-pparg: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] \| hitdisc-20261022-subset-litpcba-tp53: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.previous_value` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.
Source location shared/omics/relations.ts, used_in Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.source_locator` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.
Claimed value hitdisc-20261022-subset-litpcba-esr-ago: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] \| hitdisc-20261022-subset-litpcba-esr-antago: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] \| hitdisc-20261022-subset-litpcba-mapk1: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] \| hitdisc-20261022-subset-litpcba-pparg: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] \| hitdisc-20261022-subset-litpcba-tp53: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `attributes.value` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.
Description The five subset records linked used_in to the five-target dataset. shared/omics/relations.ts defines used_in as data to an assessment ('Dataset subset to the protocol that uses it'), so a dataset is not a legal target and the store refused the batch. The links now point at the five-target LIT-PCBA protocol. The parent dataset is already recorded in each subset's attributes.source_dataset. Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `description` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.
Relationship: subject hitdisc-20261022-protocol-shen-litpcba5 Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `links:subject:hitdisc-20261022-protocol-shen-litpcba5` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.
Name LIT-PCBA dataset subsets: used_in retargeted from a dataset to the protocol Context-only references	LIT-PCBA official project page, drugdesign.unistra.fr Original source ↗ shared/omics/relations.ts, used_in Version: Page as retrieved 2026-10-22; no version is printed on the page Retrieved: 2026-10-22T12:01:54Z	not individually reviewed No individual claim review recorded Source has a recorded evidence concern. Consult its source page before using the claim. Audit details Field: `name` Source artifact SHA-256: `a2203612b553236d7f01da5573389d439d2f7aa0436080412f27da882e086e5e` Hash scope: This is a mutable web page: artifact_sha256 describes the single retrieval of 2026-10-22T12:01:54Z and a later change to the page would change it.

How to read the evidence

Sources and history

Release 2026-10-22-1b7cf027e4f6 · Record review: source checked

1 source record and release history

LIT-PCBA official project page, drugdesign.unistra.fr · Original source · Page as retrieved 2026-10-22; no version is printed on the page

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Technical metadata and extraction receipts

Stable ID: metadata-correction-a33741d0cfa1ced7c402

areas: molecular-interactions
contexts: research
field: links
previous value: hitdisc-20261022-subset-litpcba-esr-ago: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] | hitdisc-20261022-subset-litpcba-esr-antago: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] | hitdisc-20261022-subset-litpcba-mapk1: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] | hitdisc-20261022-subset-litpcba-pparg: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}] | hitdisc-20261022-subset-litpcba-tp53: [{"relation": "used_in", "target_id": "hitdisc-20261022-dataset-litpcba-5"}]
value: hitdisc-20261022-subset-litpcba-esr-ago: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-esr-antago: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-mapk1: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-pparg: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}] | hitdisc-20261022-subset-litpcba-tp53: [{"relation": "used_in", "target_id": "hitdisc-20261022-protocol-shen-litpcba5"}]
source locator: shared/omics/relations.ts, used_in
review: method: scope-review; reviewer: claude; reviewer note: Claude review agent, independent of the extraction agent; no human review claimed; date: 2026-10-22; method note: Read the relation definition in shared/omics/relations.ts against the link the batch carried.; note: Found by the independent review pass when loading the batch. The extraction pass's own shape checker reported that every link 'resolves to a record of an allowed kind'; it did not check the relation's from and to kinds.; receipt: data/omics/use-case-coverage-hitdisc-20261022/review.json

Related records

subject: LIT-PCBA five-target screening (Shen et al. 2025 Table 4)

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